A5075149695- Additive Manufacturing and 3D Printing Technologies
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Manufacturing Process and Optimization
- Electrospun Nanofibers in Biomedical Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced Numerical Analysis Techniques
- Innovations in Concrete and Construction Materials
- Additive Manufacturing Materials and Processes
- Cellular and Composite Structures
- Wound Healing and Treatments
- 3D Shape Modeling and Analysis
- Tissue Engineering and Regenerative Medicine
- Hydrogels: synthesis, properties, applications
- Orthopaedic implants and arthroplasty
- Anatomy and Medical Technology
- Dental Implant Techniques and Outcomes
- Topology Optimization in Engineering
- Advanced Sensor and Energy Harvesting Materials
- High Entropy Alloys Studies
- biodegradable polymer synthesis and properties
- Polymer composites and self-healing
- Injection Molding Process and Properties
- Pluripotent Stem Cells Research
- Advanced Materials and Mechanics
Sabancı Üniversitesi
2016-2025
Istanbul Technical University
2020
John Wiley & Sons (United States)
2015-2017
Smith College
2017
Syracuse University
2017
University of Memphis
2017
Texas A&M University
2017
Louisiana State University Health Sciences Center New Orleans
2017
Sivas State Hospital
2015
Karadeniz Technical University
2015
Fatigue life assessment of metal additive manufacturing (AM) products has remained challenging due to the uncertainty as–built defects, heterogeneity microstructure, and residual stress. In past few years, many works have been conducted develop models in order predict fatigue AM samples by considering existence inherent defects. This review paper addresses main issues regarding parts effect defects post processing strategies. Mechanisms that are contributing failure categorized discussed...
ABSTRACT Cardiovascular diseases are the leading cause of deaths throughout world. Vascular mostly treated with autografts and blood vessel transplantations. However, traditional grafting methods have several problems including lack suitable harvest sites, additional surgical costs for harvesting procedure, pain, infection, donors, even no substitutes at all. Recently, tissue engineering regenerative medicine approaches used to regenerate damaged or diseased tissues. Most investigations been...
Abstract Three-dimensional bioprinting of cell-laden hydrogels in a sacrificial support-bath has recently emerged as potential solution for fabricating complex biological structures. Physical properties the strongly influence process and outcome fabricated constructs. In this study, we reported application composite Pluronic-nanoclay including calcium ions crosslinking agent alginate-based hydrogels. By tuning rheological properties, shear-thinning with fast self-recovery behavior was...
Abstract Using decellularized extracellular matrix (dECM) hydrogels as bioinks has been an important step forward for bioprinting of functional tissue constructs, considering their rich microenvironment and high degree biomimicry. However, directly using dECM may not be suitable processes because the loss shape fidelity geometrical precision bioprinted structure due to slow gelation kinetics. In this article, development direct hydrogel bioink from bovine Achilles tendon were presented. The...
Three-dimensional (3D) bioprinting enables the controlled fabrication of complex constructs for tissue engineering applications and has been actively explored in recent years. However, its progress limited by existing difficulties development bioinks with suitable biocompatibility mechanical properties at same time adaptability to process. Herein, we describe a nanocomposite agarose bioink tailored using 2D nanosilicate additives. The suitability 3D debated due bioinert nature compatibility...
Bacteria are one of the significant causes infection in body after scaffold implantation. Effective use nanotechnology to overcome this problem is an exciting and practical solution. Nanoparticles can cause bacterial degradation by electrostatic interaction with receptors cell walls. Simultaneously, incorporation antibacterial materials such as zinc graphene nanoparticles further enhance degradation. In present study, zinc-doped hydroxyapatite/graphene was synthesized characterized a...
The design of scaffolds with optimal biomechanical properties for load-bearing applications is an important topic research. Most studies have addressed this problem by focusing on the material composition and not coupled effect between scaffold architecture. Polymer-bioglass been investigated due to excellent bioactivity bioglass, which release ions that activate osteogenesis. However, preparation methods usually require use organic solvents induce surface modifications bioglass particles,...
Ageing population and new diseases are requiring the development of novel therapeutical strategies. 3D bioprinting an application domain additive manufacturing emerged as a potential transformative strategy for tissue engineering regenerative medicine. This paper introduces concept bioprinting, discussing in detail key requirements bio-inks main materials used to encapsulate cells. Recent advances related use smart 4D printing is also discussed. Main techniques described limitations...
This paper presents a novel computer-aided modeling of 3D tissue scaffolds with controlled internal architecture. The complex architecture is biomimetically modeled micro-architecture to satisfy different and sometimes conflicting functional requirements. A functionally gradient porosity function used vary the designed spatially mimic functionality tissues or organs. three-dimensional porous structures scaffold are geometrically partition into uniform regions offsetting operation technique...
Abstract Multimaterial additive manufacturing or three-dimensional (3D) printing of hydrogel structures provides the opportunity to engineer geometrically dependent functionalities. However, current fabrication methods are mostly limited one type material only provide functionality. In this paper, we report a novel method multimaterial deposition based on an aspiration-on-demand protocol, in which constitutive segments extruded filaments were first assembled liquid state by sequential...
Scaffold-based tissue engineering approaches have been commonly used for skin regeneration or wound healings caused by diseases trauma. For an ideal complete healing process, scaffold structures need to meet the criteria of biocompatibility, biodegradability, and antimicrobial properties, as well provide geometrical necessities damaged tissue. In this study, design, synthesis characterization a three dimensional (3D) printable copolymer based on polycaprolactone-block-poly(1,3-propylene...
Melanoma is a serious malignant skin tumor. Effectively eliminating melanoma and healing after-surgical wounds are always challenges in clinical studies. To address these problems, we propose manganese-doped calcium silicate nanowire-incorporated alginate hydrogels (named MCSA hydrogels) for situ photothermal ablation of followed by the wound process. The proposed hydrogel had controllable gelation properties, reasonable strength, excellent bioactivity due to incorporated nanowires as...
Three-dimensional (3D) bioprinting is an additive manufacturing process in which the combination of biomaterials and living cells, referred to as a bioink, deposited layer-by-layer form biologically active 3D tissue constructs. Recent advancements field show that success this technology requires development novel or improvement existing bioinks. Polyethylene glycol (PEG) one well-known synthetic has been commonly used photocrosslinkable bioink for bioprinting; however, other types...
Emerging biomanufacturing technologies have revolutionized the field of tissue engineering by offering unprecedented possibilities. Over past few years, new opportunities arose combining traditional and novel fabrication techniques, shaping hybrid designs in biofabrication. One potential application fields is skin engineering, which a combination principles wound dressing with advanced biofabrication methods could yield more efficient therapies. In this study, design fiber-reinforced...
This research investigates the accelerated hydrolytic degradation process of both anatomically designed bone scaffolds with a pore size gradient and rectangular shape (biomimetically or bricks). The effect material composition is investigated considering poly-ε-caprolactone (PCL) as main scaffold material, reinforced ceramics such hydroxyapatite (HA), β-tricalcium phosphate (TCP) bioglass at concentration 20 wt%. In case scaffolds, (200 μm, 300 μm 500 μm) also investigated. (accelerated...