A5097334847- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 detection and testing
- Viral Infections and Immunology Research
- Genomics and Phylogenetic Studies
- Bacteriophages and microbial interactions
Robert Koch Institute
2024-2025
In 2024, circulating vaccine-derived poliovirus type 2 (cVDPV2) was detected in wastewater samples Finland, Germany, Poland, Spain and the United Kingdom (UK). All strains were genetically linked, but sequence analysis showed high genetic diversity among identified within individual sites countries an unexpected proximity isolates from different countries. Taken together these results, with sequential having tested positive various sites, a broader geographic distribution beyond sampling...
ABSTRACT Time- and cost-saving surveillance of viral pathogens is achieved by tiled sequencing in which a genome amplified overlapping PCR amplicons qPCR. However, designing pan-specific primers for that have high genomic variability represents major challenge. Here, we present bioinformatics command-line tool, called varVAMP ( var iable v irus amp licons). It relies on multiple sequence alignments highly variable virus sequences enables automatic primer design qPCR or amplicon whole...