Yuanyuan Zhang

ORCID: 0000-0001-9124-8105
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About
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Research Areas
  • Tryptophan and brain disorders
  • Neuropeptides and Animal Physiology
  • Neuroscience and Neuropharmacology Research
  • Hydraulic and Pneumatic Systems
  • Receptor Mechanisms and Signaling
  • Gut microbiota and health
  • Neuroscience of respiration and sleep
  • Cavitation Phenomena in Pumps
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Epigenetics and DNA Methylation
  • Axon Guidance and Neuronal Signaling
  • Heart Rate Variability and Autonomic Control
  • Tribology and Lubrication Engineering
  • Obstructive Sleep Apnea Research

Nanjing University of Chinese Medicine
2024-2025

Anhui Jianzhu University
2024

University of Central Florida
2023

MBF Bioscience (United States)
2023

Abstract Parental substance abuse increases the risk of neurological and psychiatric disorders in offsprings. However, its underlying mechanism remains elusive. Our previous study demonstrated that long‐term exposure to methamphetamine (Meth), a psychostimulant drug with high addiction potential, remarkably alters gut microbiome metabolites male mice, which contribute Meth‐induced anxiety‐like behaviors. The current aimed investigate whether microbiota metabolism serve as potential...

10.1096/fj.202402839r article EN The FASEB Journal 2025-02-10

Lead-Bismuth Eutectic (LBE) is an interesting candidate as a coolant for Generation IV nuclear power plants. Lead-bismuth lubricated radial guide bearing the key component of mechanical pump in lead-bismuth system. In this paper, transient calculation model multiphase lubrication flow field journal established by using Singhal full cavitation and structured dynamic grid technique. Due to saturated vapors LBE being very low, effects different Non-Condensable Gas (NCG) contents on...

10.3390/lubricants12090326 article EN cc-by Lubricants 2024-09-23

Abstract Previously, we found that dCA1 A1-like polarization of astrocytes contributes a lot to the spatial memory deficit in methamphetamine abstinence mice. However, underlying mechanism remains unclear, resulting lack promising therapeutic targets. Here, mice exhibited an increased M1-like microglia and astrocytes, together with elevated levels interleukin 1α tumor necrosis factor α dCA1. In vitro, BV2 cell medium, containing high Interleukin α, which weakened their capacity for glutamate...

10.1093/cercor/bhae281 article EN Cerebral Cortex 2024-07-01

This protocol describes the process of mapping topographical organization tyrosine hydroxylase immune reactive sympathetic postganglionic axons and terminals in mouse heart. Hearts were removed separated as whole mounts, then scanned using confocal or zeiss microscopy

10.17504/protocols.io.n92ldzbmxv5b/v2 preprint EN 2023-01-19

Chronic intermittent hypoxia (CIH) is a commonly used model for sleep apnea, which constitutes major risk factor many cardiovascular diseases (CVD). Autonomic imbalance (sympathetic overactivity and parasympathetic withdrawal) hypothesized to be causal contributor of CIH-induced CVD. Previously, we showed that CIH reduced baroreflex control heart rate induced vagal cardiac motor neuronal death in the brainstem. activates central nervous system circuitry, turn enhances sympathetic outflow....

10.1152/physiol.2023.38.s1.5733941 article EN Physiology 2023-05-01
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