Prestes, J, Frollini, AB, De Lima, C, Donatto, FF, Foschini, D, de Marqueti, RC, Figueira Jr, A, and Fleck, SJ. Comparison between linear daily undulating periodized resistance training to increase strength. J Strength Cond Res 23(9): 2437-2442, 2009-To determine the most effective periodization model for strength hypertrophy is an important step conditioning professionals. The aim of this study was compare effects (LP) (DUP) on body composition maximal levels. Forty men aged 21.5 ± 8.3 with...

The application of cryotherapy is widely used in sports medicine today. Cooling could minimize secondary hypoxic injury through the reduction cellular metabolism and area. Conflicting results have also suggested delay impair regeneration process. There are no definitive findings about effects on process muscle regeneration. aim present study was to evaluate a clinical-like inflammation, extracellular matrix (ECM) remodeling Tibialis anterior (TA) rats 3, 7 14 days post-injury. It observed...

MMPs are enzymes involved in SARS-CoV-2 pathogenesis. Notably, the proteolytic activation of can occur through angiotensin II, immune cells, cytokines, and pro-oxidant agents. However, comprehensive information regarding impact different physiological systems with disease progression is not fully understood. In current study, we review recent biological advances understanding function examine time-course changes during COVID-19. addition, explore interplay between pre-existing comorbidities,...

The indiscriminate use of anabolic-androgenic steroids has been shown to induce pathologic changes in the Achilles tendon several situations.To study remodeling rats treated with combined an exercise program.Controlled laboratory study.Wistar were grouped as follows: sedentary (group I), injected only II), trained III), and IV). groups performed jumps water: 4 series 10 each, overload 50% 70% animal's body weight a 30-second rest interval between series, for 6 weeks. Anabolic-androgenic (5...

In elderly persons, weak tendons contribute to functional limitations, injuries, and disability, but re-sistance training can attenuate this age-related decline. We evaluated the effects of resistance on extracellular matrix (ECM) calcaneal tendon (CT) in young old rats its effect remodeling. Wistar aged 3 mo (young, n = 30) 20 (old, were divided into 4 groups: sedentary, trained, sedentary (OS), trained (OT). The sessions conducted over a 12-wk period. Aging showed down-regulation key genes...

Critically ill traumatic brain injury (TBI) patients experience extensive muscle damage during their stay in the intensive care unit. Neuromuscular electrical stimulation (NMES) has been considered a promising treatment to reduce functional and clinical impacts of this. However, time needed for NMES produce effects over muscles is still unclear. This study primarily aimed assess an protocol on architecture, neuromuscular electrophysiological disorder (NED), strength, secondarily, evaluate...

The aim of this study was to investigate the effects multiple cold-water immersions (CWIs) on muscle function, markers damage, systemic inflammation and ECM degradation following exercise-induced damage (EIMD). Thirty physically active males were randomly assigned either a control (n = 15) or immersion (CWI) group 15). CWI performed one (10 °C for 20 min) at post-exercise every 24 h 72 h, while remained in seated position during these corresponding periods. Muscle strength, vertical jump...

Accumulation of connective tissue, particularly extracellular matrix (ECM) proteins, has been observed in skeletal muscles with advancing age. Resistance training (RT) widely recommended to attenuate age-induced sarcopenia, even though its effects on the components that control ECM turnover remain be elucidated. Thus, aim this study was determine RT tissue content and gene expression key aged rats. Young (3 mo.) old (21 adult male Wistar rats were submitted a protocol (ladder climbing 65,...

Aging is a complex, multifactorial process characterized by the accumulation of deleterious effects, including biochemical adaptations extracellular matrix (ECM). The purpose this study was to investigate effects 12 weeks resistance training (RT) on metalloproteinase 2 (MMP-2) activity in skeletal muscles and, MMP-2 and MMP-9 blood circulation young old rats. Twenty-eight Wistar rats were randomly divided into four groups (n = 7 per group): sedentary (YS); trained (YT), (OS), (OT). stair...

Sarcopenia is a complex multifactorial process, some of which involves fat infiltration. Intramyocellular lipid (IMCL) accumulation postulated to play role on sarcopenia during aging, believed be due alterations in glucose homeostasis the skeletal muscle. Sarcopenia, along with intramuscular lipids, associated physical inactivity. Resistance training (RT) has been indicated minimize age-induced muscle adaptations. Thus, we aimed investigate effects RT mRNA levels regulatory components...

The aim of this study was to assess the effects resistance training on ladders (RTL) MMP₋₂ expression and blood lactate concentration [La−]. 30 male (3 months age), albino rats were divided into 3 groups: sedentary control (SC, n=10), low exercise (Low-IntRT, n=10) high-intensive (High-IntRT, n=10). Animals High-IntRT submitted a progressively increasing overload in relation body weight until exhaustion, while Low-IntRT group performed same regimen with no external load. program...

OBJECTIVE:We investigated the influence of resistance training on body composition and matrix metalloproteinase 2 activity in skeletal muscles rats fed a high-fat diet.METHODS: Thirty-two Wistar were divided into four experimental groups (n = 8/each) according to diet exercise status: Control (standard diet), Obese (high-fat Resistance Training diet) groups.Animals for 12 weeks promote excessive weight gain.Resistance performed periods after this period vertical ladder three times/week.Fat...

To investigate the effects of multiple cryotherapy applications after muscle injury on markers oxidative stress.Following cryolesion-induced skeletal in rats, ice was applied at injured site for 30 minutes, three times per day, day injury, and 2 days injury. determine effect treatment stress, biochemical analyses were performed 3, 7, 14 injury.Compared with non-treated animals, reduced dichlorofluorescein 7 post-injury thiobarbituric acid reactive substances levels 3 (P < 0.05)....

Aging process is characterized by a decline in the organism functionality, especially decrease of muscle function, which also affects tendons. On other hand, resistance training (RT) has been used as an important tool to increase and tendineous function during aging. Thus, this study aim verify effects RT on biomechanical properties three different aged rat For purpose, 20 wistar rats have divided into four groups (5 per group): young sedentary (YS), trained (YT), old (OS) (OT). The...

Determining how the quadriceps femoris musculotendinous unit functions, according to hip and knee joint angles, may help with clinical decisions when prescribing extension exercises. We aimed determine effect of angles on structure neuromuscular functioning all constituents patellar tendon properties. Twenty young males were evaluated in four positions: seated supine both 20° 60° flexion (SIT20, SIT60, SUP20, SUP60). Peak torque was determined during maximal voluntary isometric contraction...

Androgenic‐anabolic steroids (AAS) have been associated with an increased incidence of tendon rupture. The aim this study was to compare the biomechanical properties rat calcaneal (CT), superficial flexor (SFT), and deep (DFT), determine effect jump training in association AAS. Animals were separated into four groups: sedentary, trained, AAS‐treated sedentary rats (AAS), trained animals. Mechanical testing showed that CT differed from DFT SFT, which similar mechanical properties. Jump caused...

The aim of this study was to investigate the effects different resistance training (RT) volumes on MMP activity in skeletal muscle, visceral adipose tissue and circulation. 21 Wistar rats were randomly divided into 3 groups (n=7 per group): sedentary control (SC); RT with 4 ladder climbs (RT-4; 50, 75, 90 100% their maximal carrying capacity) 8 (RT-8 2 sets for each load). 8-week consisted climbing a 1.1-m vertical weights secured animals' tails. MMP-2 -9 analyzed by zymography. RT-8...

The aim of the present study was to evaluate effect leucine treatment (0.30 mM) on muscle weight and signaling myoproteins related synthesis degradation pathways soleus following seven days complete sciatic nerve lesion.Wistar rats (n=24) 3 4 months age (192 ± 23 g) were used. animals randomly distributed into four experimental groups (n=6/group): control, treated with (L), denervated (D) (DL).Dependent measures proteins levels AKT, AMPK, mTOR, ACC performed by Western blot. Leucine induced...