A5065536431- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Cardiac, Anesthesia and Surgical Outcomes
- Enhanced Recovery After Surgery
- Medical Imaging Techniques and Applications
- Breast Implant and Reconstruction
- Colorectal Cancer Surgical Treatments
- Cancer Risks and Factors
- Wound Healing and Treatments
- Cancer Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Reconstructive Surgery and Microvascular Techniques
- Cancer and Skin Lesions
- Hip and Femur Fractures
- Cancer, Lipids, and Metabolism
- Global Cancer Incidence and Screening
- Glioma Diagnosis and Treatment
- Head and Neck Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Cancer Cells and Metastasis
- Surgical site infection prevention
- Pressure Ulcer Prevention and Management
- Diabetic Foot Ulcer Assessment and Management
- HER2/EGFR in Cancer Research
Post Graduate Institute of Medical Education and Research
2016-2024
Institute of Medical Sciences
2024
Institute of Post Graduate Medical Education and Research
2023
All India Institute of Medical Sciences
2023
Creative Commons
2022
Christie's
2022
Index Medical College, Hospital & Research Centre
2017
Triple negative breast cancer (TNBC) is a heterogeneous disease and an attempt was made to classify TNBCs into surrogate molecular subtypes using immunohistochemical markers. Tissue microarrays were constructed for 245 cases of TNBCs. For classification immunohistochemistry done on tissue cytokeratin 5/6, 4/14 (CK5/6, CK4/14), epidermal growth factor receptor (EGFR), vimentin, E-cadherin, claudin 3 7, androgen (AR) aldehyde dehydrogenase1A. The classified basal-like 1 (BL1) type (CK5/6 + ,...
Abstract Background Cancellations of elective surgeries on the day surgery (DOS) can lead to added financial burden and wastage resources for healthcare facilities; as well social emotional problems patients. These cancellations act barriers delivering efficient surgical services. Optimal utilisation available is necessary resource‐constrained low‐and‐middle‐income countries (LMIC). This study investigates rate causes DOS in various departments across ten hospitals India. Methods A research...
Breast cancer is a heterogenous disease at the molecular level thus, it can be hypothesized that different subtypes differ in their tumor microenvironment (TME) also. Understanding TME heterogeneity may provide new prognostic biomarkers and targets for therapy. For deciphering TME, immunohistochemistry immune markers (CD3, CD4, CD8, CD68, CD163, programmed death-ligand 1), Cancer-associated fibroblast [anti-fibroblast activating protein α (FAP-α), platelet-derived growth factor receptor...
Accurate recurrence risk assessment in hormone receptor positive, HER2/neu negative breast cancer is critical to plan precise therapy. CanAssist Breast (CAB) assesses based on tumor biology using artificial intelligence-based approach. We report CAB correlating with disease outcomes multiple clinically high- and low-risk subgroups. In this retrospective cohort of 925 patients [median age-54 (22-86)] had hazard ratio (HR) 3 (1.83-5.21) 2.5 (1.45-4.29), P = 0.0009) univariate multivariate...
BACKGROUND: Wound-related infections and complications are rare after day care laparoscopic cholecystectomy (LC). They can have a significant adverse impact on the postoperative course an uneventful elective LC. The use of topical antibiotics over port site may prevent such complications. MATERIALS AND METHODS: This trial was conducted from January 2018 to June 2019. Two hundred fifty patients who met inclusion exclusion criteria were included in study. randomized into antibiotic group...
BACKGROUND: Tumour microenvironment (TME) contributes to resistance anti-cancer drugs through multiple mechanisms including secretion of pro-survival factors by cancer associated fibroblasts (CAFs). In this study, we determined the chemotherapy producing potential CAFs in molecular subtypes breast cancer. METHODS: The were isolated from fresh lumpectomy/mastectomy specimens different cultured and secretome was collected each subtype. Breast cell lines MCF-7, SK-BR3, MDA-MB-231, MDA-MB-468...
Endoscopic-assisted surgery for breast tumors has the advantage of inconspicuous scars, less volume loss, and nipple areolar distortion. A novel endoscopic-assisted technique through inframammary fold excision fibroadenomas is presented.
Globally, most of the randomised trials with hypofractionation in patients breast cancer have used 3-dimensional conformal radiotherapy technique (3D-CRT). As facilities for 3D-CRT may not be available low-resource settings, there is a need to see if feasible and safe 2-dimensional (2-D) technique. In this study, we compared 3-week radiation schedule 2-week hypofractionated 2-D
Background In general surgery, a clinician is commonly required to break bad news. However, training in communication not part of the formal curriculum either medical school or surgical residency and there paucity data on awareness SPIKES (Setting up interview, Perception, Invitation, Knowledge sharing, Emotion, Strategy Summary) protocol among practising surgeons residents India. Methods We did cross-sectional study Department General Surgery at our institution. Junior were invited take...
Excision of nonpalpable breast lesions requires intraoperative guidance. Wire-guided localization and ultrasounds have been used successfully but suffer from some disadvantages. We describe a new modification the standard technique using combination preoperative ultrasound in conjunction with wire-guided localization.Wire ultrasound-guided (WUGL) was for excision lesions.Sixty-nine patients were subjected to WUGL, out whom 63 had diagnosis invasive/noninvasive cancer. Six benign lesions,...
18F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is now recognized as a staging investigation for locally advanced breast cancer. This retrospective review of data was performed to correlate the maximum standardized uptake value (SUVmax) primary tumor with molecular subtype cancer.Patients biopsy-proven, treatment naïve, Stage III cancer, whom 18F-FDG PET/CT and immunohistochemistry 4 available were included in study. Correlations deduced between...
No conflicts of interest to disclose.
The enhanced recovery after surgery (ERAS) program established improved clinical outcomes in elective surgery; however, its role emergencies is uncertain. This study was designed to assess the feasibility, safety, and efficacy of a tailored-ERAS (t-ERAS) protocol patients undergoing modified Graham's patch closure for gastro-duodenal perforation.A single-centre, prospective, parallel-arm, open-label, randomized controlled trial conducted from February 2021 December 2021. Patients with...
Abstract Mucinous carcinomas are a rare type of invasive breast carcinoma characterized by large quantities extracellular mucin on histopathological examination. These tumors can be easily missed or misdiagnosed. Due to mucin, these presumed “soft” masses. This pilot study aims evaluate the strain and shear wave elastography features tumors. Out 485 referred patients with cancer between November 2022 January 2023, 8 cases were diagnosed as mucinous histopathology. evaluated ultrasound in...
Abstract INTRODUCTION There is an increasing focus of the treating clinicians on issues related to quality life and sexual functioning in breast cancer survivors. This even more important developing countries like India as incidence young also significant here. However, despite this, there little data from factors affecting Hence, we decided perform this study. METHODS Patients who had undergone surgery for within last 2-5 years were included. having psychiatric illness excluded so patients...
Purpose or Learning Objective: To evaluate the efficacy of multiparametric magnetic resonance imaging (MRI) in differentiating between benign and malignant soft tissue lesions.