Zezhi Li

ORCID: 0000-0001-9149-5800
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About
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Research Areas
  • Schizophrenia research and treatment
  • Tryptophan and brain disorders
  • Diet and metabolism studies
  • Long-Term Effects of COVID-19
  • Bipolar Disorder and Treatment
  • Psychosomatic Disorders and Their Treatments
  • COVID-19 and Mental Health
  • Resilience and Mental Health
  • Mental Health and Psychiatry
  • Family Caregiving in Mental Illness
  • Psychopathy, Forensic Psychiatry, Sexual Offending
  • Mindfulness and Compassion Interventions
  • Mental Health Treatment and Access
  • Child and Adolescent Psychosocial and Emotional Development
  • Genomics, phytochemicals, and oxidative stress
  • Healthcare Decision-Making and Restraints
  • Hypothalamic control of reproductive hormones
  • Gut microbiota and health
  • Folate and B Vitamins Research
  • Smoking Behavior and Cessation
  • Emergency and Acute Care Studies
  • Stress Responses and Cortisol
  • Electrolyte and hormonal disorders
  • Probiotics and Fermented Foods
  • Dementia and Cognitive Impairment Research

Guangzhou Medical University
2022-2025

Nanjing Medical University
2025

Guangzhou Psychiatric Hospital
2022-2024

Abstract Patients with schizophrenia (SCZ) smoke up to three times more than general people. However, there are conflicting results regarding the relationship between tobacco and clinical symptom severity in SCZ. The aim of this study was assess impact smoking on symptoms after antipsychotic treatment a 12-week cohort controlling for confounding factors. One hundred forty-five male patients drug-naïve first-episode (DNFE) SCZ received monotherapy 12 weeks. Symptom assessed at baseline week...

10.1038/s41537-024-00449-1 article EN cc-by Schizophrenia 2024-03-15

Alexithymia is a common, but less-recognized affective deficit in patients with schizophrenia. To date, no definitive conclusions have been drawn about the relationship between alexithymia and clinical symptoms or their correlates, particularly stable The purpose of this study was to investigate link psychopathological symptoms, as well any associated A total 435 Chinese schizophrenia were recruited. Positive Negative Symptoms Scale (PANSS) used evaluate each patient's symptoms. Toronto...

10.1007/s00406-022-01492-8 article EN cc-by European Archives of Psychiatry and Clinical Neuroscience 2022-10-14

Objective This study aims to identify the clinical characteristics of schizophrenia, depression, and AD among older adults. Methods General information patients was collected, including diagnosis, age, gender, level education, marital status, drinking behavior, smoking course mental disorder, type admission, history modified electroconvulsive therapy (MECT) hospitalization period. The Brief Psychiatric Rating Scale (BPRS), Geriatric Depression (GDS), Generalized Anxiety Disorder 7-Item...

10.3389/fpsyt.2025.1486626 article EN cc-by Frontiers in Psychiatry 2025-03-12

Schizophrenia patients with violent behavior are a severe public health concern, but the correlates of this unknown. Additionally, relationship between neurocognitive function and in Chinese schizophrenia has not yet been investigated. A total 337 inpatients were recruited. The Positive Negative Syndrome Scale (PANSS) was used to assess psychopathological symptoms. Neurocognitive functioning evaluated using Repeatable Battery for Assessment Neuropsychological Status (RBANS). percentage 10.4%...

10.3389/fpsyt.2022.1087372 article EN cc-by Frontiers in Psychiatry 2023-01-19

Abstract Objectives Emerging evidence indicates a connection between oxidative stress, immune-inflammatory processes, and the negative symptoms of schizophrenia. In addition to possessing potent antioxidant anti-inflammatory properties, sulforaphane (SFN) has shown promise in enhancing cognitive function among individuals with This study aims investigate efficacy combined treatment SFN patients schizophrenia who experience its effect on levels superoxide dismutase (SOD) inflammatory marker,...

10.1007/s00406-023-01679-7 article EN cc-by European Archives of Psychiatry and Clinical Neuroscience 2023-09-20

To investigate the status of anxiety, depression, and psychological resilience among individuals with COVID-19, their interrelationships to provide a scientific basis for developing intervention strategies these patients.

10.1002/brb3.3274 article EN cc-by Brain and Behavior 2023-11-01

Aim This study investigated the impact of an 8‐month daily‐guided intensive meditation‐based intervention (iMI) on persistent hallucinations/delusions and health‐related quality life (QoL) in male inpatients with schizophrenia treatment‐refractory hallucinations delusions (TRHDs). Methods A randomized controlled trial assigned 64 TRHD equally to iMI plus general rehabilitation program (GRP) or GRP alone. Assessments were conducted at baseline third eighth months using Positive Negative...

10.1111/pcn.13641 article EN Psychiatry and Clinical Neurosciences 2024-02-06

Objective Sex differences have been observed in many aspects of schizophrenia, including cognitive deficits. Despite extensive research into the relationship between metabolic factors and deficits few studies explored potential sex difference their association.Methods We recruited 358 schizophrenia patients 231 healthy controls. The participants underwent measurements body mass index (BMI), waist circumference, blood pressure, triglycerides, high-density lipoprotein cholesterol, fasting...

10.30773/pi.2023.0105 article EN Psychiatry Investigation 2023-10-24

Background: Elevated homocysteine levels and late‐life depression are risk factors for cognitive decline: a comparative study highlighted the association of late‐onset (LOD) with more significant deficits brain pathology than early‐onset (EOD). Limited research has explored possible interaction between their correlation performance in patients EOD LOD. Methods: Fifty‐seven individuals EOD, 56 LOD, 89 matched healthy controls (HC) were recruited. Global cognition, memory, execution, language,...

10.1155/2024/7919736 article EN cc-by Depression and Anxiety 2024-01-01
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