- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Diabetes Treatment and Management
- Cardiac Imaging and Diagnostics
- Potassium and Related Disorders
- Blood Pressure and Hypertension Studies
- Cardiac Structural Anomalies and Repair
- Advanced MRI Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Cardiac pacing and defibrillation studies
- Cardiac Health and Mental Health
- Cardiovascular and exercise physiology
- Erythropoietin and Anemia Treatment
- Hemodynamic Monitoring and Therapy
- Infective Endocarditis Diagnosis and Management
- Pulmonary Hypertension Research and Treatments
- Geographic Information Systems Studies
- Dialysis and Renal Disease Management
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Emergency and Acute Care Studies
- Heart rate and cardiovascular health
- Membrane-based Ion Separation Techniques
- Cardiovascular Effects of Exercise
Hospital Clínico Universitario de Valencia
2020-2025
Universitat de València
2020-2025
Centro de Investigación en Red en Enfermedades Cardiovasculares
2025
INCLIVA Health Research Institute
2023-2024
GTx (United States)
2021
Navarro College
2021
Centro de Investigación y Tecnología Agroalimentaria de Aragón
2021
Universidad de Zaragoza
2021
Institute of Cardiology
2020
Complejo Hospitalario Torrecárdenas
2012
We aimed to determine whether treatment with sildenafil improves outcomes of patients persistent pulmonary hypertension (PH) after correction valvular heart disease (VHD).
Intrarenal venous flow (IRVF) measured by Doppler ultrasound has gained interest as a potential surrogate marker of renal congestion and adverse outcomes in heart failure. In this work, we aimed to determine if antigen carbohydrate 125 (CA125) plasma amino-terminal pro-B-type natriuretic peptide (NT-proBNP) are associated with congestive IRVF patterns (i.e., biphasic monophasic) acute failure (AHF).We prospectively enrolled consecutive cohort 70 patients hospitalized for AHF. Renal was...
Mineralocorticoid receptor antagonists (MRA) improve outcomes in patients with heart failure and reduced ejection fraction (HFrEF) but are underused clinical practice. Observational data suggest that hyperkalemia is the leading obstacle for suboptimal use of MRA.
Introduction: Antigen carbohydrate 125 (CA125) has emerged as a proxy of fluid overload and inflammation in acute heart failure (AHF). We aimed to evaluate the influence dapagliflozin on CA125 levels within first weeks after discharge whether changes were related 6-month adverse clinical outcomes. Methods: In this retrospective observational study, data from 956 AHF patients discharged tertiary hospital analyzed. assessed during index admission (visit 1) at median 26 (15-39) days 2). The...
The impact of sex in patients with CAD has been widely reported, but little is known about the influence on risk new-onset HF or suspected CAD. We aimed to examine sex-related differences and heart failure (HF) coronary artery disease (CAD) undergoing vasodilator stress cardiac magnetic resonance (CMR).We prospectively evaluated 5899 consecutive HF-free submitted CMR for Ischaemic burden (number segments stress-induced perfusion deficit) left ventricular ejection fraction (LVEF) were...
Background Following a heart failure (HF)‐decompensation, there is scarce data about sex‐related prognostic differences across left ventricular ejection fraction (LVEF) status. We sought to evaluate in 6‐month mortality risk LVEF following admission for acute HF. Methods and Results retrospectively evaluated 4812 patients consecutively admitted HF multicenter registry from 3 hospitals. Study end points were all‐cause, cardiovascular, HF‐related at follow‐up. Multivariable Cox regression...
Abstract We aimed to assess the association between CA125 and long-term risk of total acute heart failure (AHF) admissions in patients with an index hospitalization AHF preserved ejection fraction (HFpEF). prospectively included 2369 2008 2019 three centers. NT-proBNP were measured during early evaluated as continuous categorized quartiles (Q). Negative binomial regressions used recurrent admission. The mean age sample was 76.7 ± 9.5 years 1443 (60.9%) women. Median values 38.3 (19.0–90.0)...
Background The clinical impact of heart rate (HR) in failure with preserved ejection fraction (HFpEF) is a matter debate. Among those HFpEF, chronotropic incompetence (CI) has emerged as pathophysiological mechanism linked to the severity disease. In this study, we sought evaluate whether admission acute differs along left ventricular (LVEF).
Ovine anaplasmosis is a vector-borne disease caused by Anaplasma ovis and mainly transmitted through tick bites. In Spain, the first outbreak of ovine occurred in 2014. An epidemiological study fifty-one farms was carried out associated with this affected geographical area. questionnaire performed. addition, whole blood samples were taken for molecular analysis 47 these to determine prevalence infection ovis. A. present 44 PCR-analysed (93.6%). However, only 40.4% studied showed severe...
Abstract Aims Iron deficiency (ID) is a frequent finding in patients with chronic and acute heart failure (AHF) along the full spectrum of left ventricular ejection fraction (LVEF). has been related to systolic dysfunction, but its role right function not evaluated. We sought evaluate whether ID identifies greater dysfunction setting AHF. Methods results prospectively included 903 admitted Right was evaluated by tricuspid annular plane excursion (TAPSE) ratio TAPSE/pulmonary artery pressure...
Heart failure with preserved ejection fraction (HFpEF) often coexists chronic kidney disease (CKD). Exercise intolerance is a major determinant of quality life and morbidity in both scenarios. We aimed to evaluate the associations between N-terminal pro-B-type natriuretic peptide (NT-proBNP) carbohydrate antigen 125 (CA125) maximal aerobic capacity (peak VO