Glutinous rice starch (GRS) is commonly produced in the Northeast of Thailand. GRS a biopolymer which widely used food industry but not yet applied within pharmaceutical as an alternative resource. exhibits branch chain structure feasible to fabricate nanofiber. Therefore, combining with polyvinyl alcohol (PVA) hybrid form can be potential platform produce GRS-PVA nanofibers. Smooth nanofibers 2% (w/v) combined 8% PVA were fabricated by electrospinning process. A scanning electron microscope...

Cissus quadrangularis Linn. (CQ) has been used in Indian and Thai traditional medicine for healing bone fractures because of numerous active ingredients CQ. It is still unclear which compounds are the formation.The molecular docking technique, ethanolic extraction along with hexane fractionation, an vitro experiment a human osteoblast cell line (MG-63) were to narrow down compounds, prepare CQ extract, test biological activities, respectively.The technique revealed that quercetin...

This is the first study to investigate effect of ethanol concentrations on phenolic content and biological activities Sripanya Punica granatum peel extract. Various ethanol, (20 80% v/v), were used in maceration process. Extracts investigated for total by Folin–Ciocalteu method, antioxidant 1,1-diphenyl-2-picrylhydrazyl (DPPH) 2,2’-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay, anti-tyrosinase activity a spectrophotometric method. The chemical composition was using...

Five glutinous purple rice cultivars and non-glutinous cultivated in different altitudes the north of Thailand were collected. The samples extracted using ethanol determined for anthocyanins HPLC. total phenolic content (TPC), flavonoid (TFC), antioxidant, anti-inflammatory, antimicrobial activities against foodborne pathogens investigated. highland cultivar named Khao' Gam Luem-Phua (KGLP) extract had significantly high levels cyanidin 3-O-glucoside, peonidin delphinidin TPC, TFC, as well...

Resistant starch (RS), a current health trend, can be obtained from various natural sources. Musa sapientum Linn., ABB group, cv. Kluai Namwa Luang is good source of RS. This the first study to investigate physicochemical properties, RS contents, and prebiotic properties unpeeled raw banana powder (URB), peeled (PRB), (BS) Luang. Their were characterized by scanning electron microscope, differential calorimeter, X-ray diffractometer. The contents determined using Megazyme Starch Assay Kit....

Colorectal cancer occurs due to various factors. The important risks are dietary lifestyle and inflammatory bowel diseases, such as Crohn’s disease ulcerative colitis. It has been found that the inhibitory enzyme cyclooxygenase-2 (COX-2) in colorectal region can potentially reduce risk of cancer. present study investigated rice bran oil from natural purple bran, which exhibits antioxidant anti-inflammatory activity. This aimed evaluate bioactive compound content (NPRBO) derived native Thai...

This study aimed to the biotransformation of indigenous northern Thai purple rice using β-glucosidase-producing Lactobacillus (BGPL) increase content bioactive anthocyanin for colorectal chemoprevention and immunization. BGPL, namely, FR 332, was first isolated from fermented foods. Indigenous rice, Khao' Gam Leum-Phua (KGLP), selected by L. plantarum FR332 according highest amounts cyanidin-3-glucoside. The determination quantities revealed that cyanidin detected after 12 h...

Deoxypreussomerin derivatives, palmarumycins JC1 (1) and JC2 (2), two dimeric naphthoquinones, isodiospyrin (3) its new derivative isodiospyrol A (4), were isolated from dried fruits of Diospyros ehretioides. Structures the compounds elucidated by spectroscopic analyses. Palmarumycins not found in extract freshly collected fruits; however, they present fruit extract. The absence fresh D. ehretioides, together with chemotaxonomic point view, we proposed that (2) are more likely to be fungal...

In this work, molecular docking, pharmacophore modeling and dynamics (MD) simulation were rendered for the mouse P-glycoprotein (P-gp) (code: 4Q9H) bioflavonoids; amorphigenin, chrysin, epigallocatechin, formononetin rotenone including a positive control; verapamil to identify protein-ligand interaction features binding affinities, characteristics, hot-spot amino acid residues complex stabilities. These flavonoids occupied same site with high affinities shared key their interactions region...

A sustainable procedure offering green, simple, and rapid analysis was developed to determine benzalkonium chloride (BKC) in pharmaceutical preparations. The determination using smartphones based on the ion pair colorimetric reaction with bromothymol blue (BTB), which produces a yellow color. intensity of product color, is proportional concentration BKC, detected evaluated smartphone camera an image processing application. performed microliter rapidly within 1 min after incubation. This...

Hydroethanolic longan (Dimocarpus Lour.) leaf extract has reported remarkable biological activities related to the aging process for use in cosmeceuticals. Finding bioactive chemical marker (BCM) could play a crucial role cosmeceutical manufacturers guaranteeing quality of and its efficacy. This study aimed select most potential BCM established predicted anti-aging skin hydroethanolic extract. The assessment was determined by evaluating vitro antioxidant activities, including...

The fabrication of mangiferin nanoparticles using an electrospraying technique is a new and promising method for developing with higher efficiency safety. This study aimed to fabricate (MNPs) cellulose acetate (CA) as polymer at various parameters electrospraying. Commercial (CM) was purified from 88.46 95.71% by recrystallization improve its purity biological activities remove any residue. properties recrystallized (RM) were characterized DSC, FTIR, X-ray diffraction (XRD) HPLC. Then...

Inhibition of P-glycoprotein (P-gp)'s function may conduct significant changes in the prescription drugs' pharmacokinetic profiles and escalate potential risks taking place drug/herb-drug interactions. Computational modeling was advanced to scrutinize some bioflavonoids which play roles herb-drug interactions as P-gp inhibitors utilizing molecular docking pharmacophore analyses. Twenty-five flavonoids were utilized ligands for modeling. The mouse (code: 4Q9H) acquired from PDB. operated...

Objective: Rice straw is an agricultural waste material which has a negative impact on the environmental. This study’s aim was to prepare high-performance rice activated charcoal (RSAC) for cosmetic and pharmaceutical applications using chemical activation technique.Methods: Three cultivars of namely Dok Mali 105 (DM105), RD6 Niaw San-Pah-Tawng were selected determine lignin content. The with highest content produce charcoal. particle size 20, 40 60 mesh carbonized at 200, 300, 400, 500 600...

Lactobacillus is a beneficial bacteria that could inhibit pathogenic potential of other microorganisms. This the first study to develop tablet from Musa sapientum Linn. (locally known as Kluai Namwa) using direct compression method support sp. We compared amount resistant starch and prebiotic properties dry powder unpeeled raw fruit, peeled M. sapientum. These powders were formulated into tablets evaluated for their index native powder. Resistant starch, which possessed highest index,...

Mango (Mangifera indica L.) is one of the most economically important fruits in Thailand. has been used as a traditional medicine because it possesses many biological activities, such antioxidant properties, anti-inflammatory microorganism-growth inhibition, etc. Among its natural pharmacologically active compounds, mangiferin main component found mango leaves. Mangiferin potential to treat variety diseases due multifunctional activities. This study aims prepare mangiferin-rich extract (MRE)...