The efficient pretreatment of lignocellulosic biomass is essential for cellulose valorization. This work investigated the fractionation efficiency process based on natural acidic deep eutectic solvent (NADES) isolating cellulose-rich materials (CRM) from coffee parchment (CP). results showed that NADES, composed choline chloride, oxalic acid, and water in a 2:2:1 molar ratio, was most CP fractionation. sequential using NADES under microwave heating (MW-NADES) at 130 °C 15 min, followed by...

Sambucus javanica subsp. (SJ) has been used in traditional medicine the northern region of Thailand for healing bone fractures; however, studies on how this plant stimulates formation are still scarce. The present study aimed to investigate potential crude extracts and fractions obtained from SJ leaves osteoporotic protection. All samples were investigated murine preosteoblast MC3T3-E1 cells resorption biomarkers, namely alkaline phosphatase (ALP), osteocalcin (OC), osteoprotegerin (OPG),...

Polyhydroxybutyrate-co-hydroxyvalerate (PHBV) is considered a suitable polymer for drug delivery systems and bone tissue engineering due to its biocompatibility biodegradability. However, the lack of bioactivity antibacterial activity hinders biomedical applications. In this study, mesoporous bioactive glass nanoparticles (MBGN) were incorporated into PHBV enhance bioactivity, while cinnamaldehyde (CIN) was loaded in MBGN introduce antimicrobial activity. The blank (PHBV/MBGN) CIN-loaded...

Cognitive frailty (CF) is defined by the coexistence of physical and mild cognitive impairment. Malnutrition an underlying factor age-related conditions including frailty. However, evidence associating malnutrition limited. This cross-sectional study aimed to determine association between CF in elderly. A total 373 participants aged 65–84 years were enrolled after excluding those who suspected have dementia depression. Then, 61 45 normal randomly selected measure serum prealbumin level....

Cissus quadrangularis Linn. (CQ) has been used in Indian and Thai traditional medicine for healing bone fractures because of numerous active ingredients CQ. It is still unclear which compounds are the formation.The molecular docking technique, ethanolic extraction along with hexane fractionation, an vitro experiment a human osteoblast cell line (MG-63) were to narrow down compounds, prepare CQ extract, test biological activities, respectively.The technique revealed that quercetin...

Zingerone, an active compound that is present in cooked ginger, has been claimed to be a bioactive ingredient holds the potential of preventing and/or treating diseases involving inflammation. In this study, zingerone was used discover its properties against joint inflammation using interleukin-1β-induced osteoarthritis cartilage explant and cell culture models. Zingerone supplemented into media at different concentrations along with presence interleukin-1β, inducer osteoarthritis. Markers...

An extended duration of breastfeeding up to two years is encouraged by many health authorities, but information regarding the composition milk after one year postpartum limited. The goal this study was determine association between lactation and macronutrient contents, immunoglobulin A (IgA) levels total antioxidant capacity (TAC) in human (HM), from 1 24 months postpartum.Cross-sectional samples were collected January April 2019 mothers with healthy full-term children who had been lactating...

Sclerostin, an antagonist of the Wnt/β-catenin signaling pathway, was discovered as a potential therapeutic target for stimulating bone formation in osteoporosis. In this study, molecular docking employed to predict binding 29 herbal compounds, which were reported stimulators, loop2 region sclerostin. Then, 50 ns dynamics (MD) simulation complexes between sclerostin and top 10 hits obtained from carried out. Root mean square deviations (RMSDs) analysis MD trajectories pointed out that all...

The poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) derived from cyanobacteria is an environmentally friendly biodegradable polymer. low yield of PHBV’s production the main hindrance to its sustainable production, and manipulation PHBV processes could potentially overcome this obstacle. present research investigated evolutionarily divergent obtained local environments Thailand. Among strains tested, Cyanosarcina sp. AARL T020, a hot spring cyanobacterium, showed high rate accumulation...

The indigenous purplish red fruit,

The percentage of infants receiving frozen human milk (HM) is increasing. effects thawing and warming on the secretory immunoglobulin A (SIgA) level lysozyme activity in HM should be investigated to identify optimal methods for preserving immune factors HM.Milk samples were collected from 40 mothers with healthy full-term who had been lactating one six months. baseline analyzed within 24 h after collection, other at -18 °C before analyses. We compared two methods: placing container overnight...

: Storage and warming can impact the protein concentration of breast milk (BM). This study aimed to explore effects routine BM handling, from storage warming, on concentration.

The magnetic bioglass-ceramics were introduced for hyperthermia treatment of bone cancer. aim this work was to study the properties ferrimagnetic glass-ceramics from SrFe12O19(SF)-SiO2-CaO-Na2O-P2O5 system by using modified solid-state sintering method. results showed that sodium calcium silicate (Na4Ca4Si6O18), strontium iron oxide (SrFe12O19) and (Fe2O3) precipitated in all samples. saturation magnetization (Ms), remanence (Mr) coercivity (Hc) increased addition SF bioglass. samples soaked...

Context In order to maintain the availability of meat from indigenous chicken types in remote Asian regions with their special quality, novel ways increasing efficiency are needed. One way could consist crossbreeding layer type chickens that genetically quite distant breeds. Aim The three hypotheses tested were as follows: quality differs broilers; male resembles rather than and crossbreds overall superior respective purebreds. Methods We studied carcass Thai Pradu Hang Dam (PD) Rhode Island...

As Thailand moves toward an aging society, frailty has become a concern amongst northern Thai elderly. The causes of are multifactorial and include genetic, environmental, socio-economic factors; diet is particular interest. A cross-sectional study was conducted from September to October 2017 investigate what kind diets normally consumed by 350 elders were associated with using questionnaire determination Fried’s phenotype followed phytochemical analyses the diets. multivariable logistic...

Sesamin, a significant lignin compound isolated from sesame (Sesamum indicum Linn), is well known for its antioxidant, anti-inflammatory, and tissue growth promotion properties. Bioabsorbable poly(ε-caprolactone) (PCL) also well-known polymer applied to various fields of medicine as biomaterials. The main objective this research was produce prototype material PCL sesamin by electrospinning technique bone engineering applications. Dichloromethane dimethylformamide (7:3) mixture used the...

Reactive oxygen species (ROS) contribute to cancer growth and metastasis. Using antioxidants modulate cellular ROS levels is a promisingstrategy for prevention treatment. Calophyllum inophyllum L., or tamanu, medicinal plant renowned its anti-inflammatory, antioxidant, anticancer properties in traditional medicine systems. However, the effects of C. extract on remain unexplored. This study represents first report such provides potential mechanisms underlying extract. The branches were...

“People-Forest-Miang” communities are villages located in the cultivated area of Camellia sinensis var. assamica, or Cha Miang, northern Thailand. Miang forests a form agriculture relying on forest-rich bioresources. This study focuses survey diversity medicinal plants used by Mae Kampong Village, Chiang Mai, The results demonstrated that 73 species were to prevent and treat various ailments. highest number (30.14%) was for musculoskeletal system disorders, followed digestive disorders...

Owing to its excellent mechanical properties and aesthetic tooth-like appearance, lithium disilicate glass–ceramic is more attractive as a crown for dental restorations. In this study, glass–ceramics were prepared from SiO2–Li2O–K2O–P2O5–CeO2 glass systems with various Al2O3 contents. The mixed was then heat-treated at 600 °C 800 2 h form samples. Phase formation, microstructure, bioactivity investigated. phase formation analysis confirmed the presence of Li2Si2O5 in all sample an content 1...

Background The spread of artemisinin (ART)-resistant Plasmodium falciparum threatens the control malaria. Mutations in propeller domains P. Kelch13 ( k13 ) are strongly associated with ART resistance. Ferredoxin (Fd), a component ferredoxin/NADP + reductase (Fd/FNR) redox system, is essential for isoprenoid precursor synthesis plasmodial apicoplast, which important K13-dependent hemoglobin trafficking and activation. Therefore, Fd an antimalarial drug target fd mutations may modulate...