- Polymer composites and self-healing
- Fluid Dynamics and Turbulent Flows
- Spine and Intervertebral Disc Pathology
- Heat Transfer Mechanisms
- Turbomachinery Performance and Optimization
- Spondyloarthritis Studies and Treatments
- Advanced Sensor and Energy Harvesting Materials
- Aerodynamics and Acoustics in Jet Flows
- Advanced MRI Techniques and Applications
- Advanced Polymer Synthesis and Characterization
- Polymer Nanocomposites and Properties
- Plasma and Flow Control in Aerodynamics
- Epigenetics and DNA Methylation
- Electrospun Nanofibers in Biomedical Applications
- Computational Drug Discovery Methods
- Ferroelectric and Negative Capacitance Devices
- Kruppel-like factors research
- Cytokine Signaling Pathways and Interactions
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Flame retardant materials and properties
- Musculoskeletal pain and rehabilitation
- Carbon dioxide utilization in catalysis
- Advanced Memory and Neural Computing
- Ammonia Synthesis and Nitrogen Reduction
- Advanced Neuroimaging Techniques and Applications
Collaborative Innovation Center of Advanced Microstructures
2024
Nanjing University
2024
Central South University
2024
Air Force Medical University
2020-2024
Xijing Hospital
2020-2024
Fudan University
2024
Sichuan University
2020-2024
Sichuan Agricultural University
2024
Harbin Institute of Technology
2017-2023
Tianjin University of Technology
2023
Significance Glassy polymers are widely used as structural materials in aerospace vehicles, airplanes, automobiles, biomedical devices, and so on. However, glassy difficult to self-heal at room temperature due their frozen molecules. For example, the window glass of airplanes made polycarbonate cannot repair mechanical damages autonomously, which could lead a catastrophe. To impart with self-healing ability, we take advantage high mobility hyperbranched polymers, introduce hydrogen...
Loose connective tissue that widely exists in the human body is very tough and healable, due to unique network formed by hyperbranched linear fibers. Inspired such structure, we develop a class of healable polymeric glasses (THGs) tailoring amine-carboxylate salt bridges between polymer high-molecular-weight copolymers. The high density leads yield strength (up 49.7 MPa) Young's modulus (1.1 GPa) THGs. Meanwhile, large free volume molecular entanglements copolymers enable outstanding...
Natural rubber (NR) material is indispensable in various fields of our daily life, while its preparation usually involves toxic cross-linking agents and energy-consuming vulcanization processes. The permanent network NR products also makes degradation recycling difficult. Herein, a fully biosourced, vulcanization-free developed by simply introducing carrageenan (KC) the matrix via facile aqueous mixing method. nonrubber components (NRCs) on latex particles are crucial importance for this art...
In this paper, the graphene oxide loaded with nano titanium dioxide (TiO2-GO) was synthesized through 3-isocyanatopropyltrimethoxysilane (IPTMS) and characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction analysis (XRD), photoelectron (XPS), scanning electron microscopy (SEM), thermogravimetric (TGA), dispersion test. The results illustrated our modification successful TiO2-GO transferred from hydrophilic to hydrophobic. That greatly enhanced dispersity of in epoxy...
Objectives: Intervertebral disc degeneration is a progressive and chronic disease, usually manifesting as low back pain. This study aimed to screen effective biomarkers for medical practice well figuring out immune infiltration situations between circulation intervertebral discs. Methods: Gene expression profiles of GSE124272 was included differentially analysis, WGCNA analysis from GEO database, other GSE series were used validation datasets. A methods conducted verify the robustness hub...
Suppressing vibrations and noises is essential for our automated society. Here, inspired by the hierarchical dynamic bonds phase separation of mussel byssal threads, we synthesize high-damping supramolecular elastomers (HDEs) via simple one-pot radical polymerization butyl acrylate (BA), acrylic acid (AA), vinylimidazole (VI). Interestingly, AA VI not only form hydrogen ionic simultaneously but also segregate into aggregates different sizes, thereby successfully mimicking structure threads....
A healable poly(urethane-urea) elastomer with ultra-high mechanical strength enabled by tailoring multiple relaxation dynamics of hierarchical hard domains.
Abstract The growing concern regarding widespread plastic pollution has propelled the development of sustainable self‐healing plastics. Although considerable efforts have been dedicated to fabricating plastics, achieving rapid healing at room temperature is extremely challenging. Herein, we developed an ultra‐fast‐healing glassy polyurethane (UGPU) by designing a hyperbranched molecular structure with high density multiple hydrogen bonds (H‐bonds) on compliant acyclic heterochains and...
Electrified synthesis of high-value organonitrogen chemicals from low-cost carbon- and nitrogen-based feedstocks offers an economically environmentally appealing alternative to traditional thermocatalytic methods. However, the intricate electrochemical reactions at electrode surfaces pose significant challenges in controlling selectivity activity, especially for producing complex substances such as
Intervertebral disk degeneration (IDD) is a chronic inflammatory disease with intricate connections between immune infiltration and oxidative stress (OS). Complex cell niches exist in degenerative intervertebral (IVD) interact each other regulate the homeostasis together. However, few studies have used longitudinal approach to describe response of IDD progression. Here, we conducted conjoint analysis bulk-RNA sequencing single-cell sequencing, together series techniques like weighted gene...
The sweeping jet actuator (SJA), a type of fluid oscillator, has attracted considerable attention in the areas enhanced heat transfer and flow control. In this study, an unsteady Reynolds-averaged Navier–Stokes numerical investigation (k–ω baseline) was conducted to evaluate mechanisms characteristics (SJ) on confined concave surface. A conventional oscillating with unit aspect ratio used generate SJ. at target surface details inside field are discussed detail analyze mechanism effect SJ...
Degenerative disc disease (DDD), a major contributor to discogenic pain, which is mainly resulted from the dysfunction of nucleus pulposus (NP), annulus fibrosis (AF) and cartilage endplate (CEP) cells. Genetic cellular components alterations in CEP may influence homeostasis, while few single-cell RNA sequencing (scRNA-seq) report makes it challenge evaluate heterogeneity CEP. Here, this study conducted first conjoint analysis weighted gene co-expression network (WGCNA) scRNA-seq CEP,...
Abstract The growing concern regarding widespread plastic pollution has propelled the development of sustainable self‐healing plastics. Although considerable efforts have been dedicated to fabricating plastics, achieving rapid healing at room temperature is extremely challenging. Herein, we developed an ultra‐fast‐healing glassy polyurethane (UGPU) by designing a hyperbranched molecular structure with high density multiple hydrogen bonds (H‐bonds) on compliant acyclic heterochains and...
A moisture-resistant glassy plastic (MRGP) with hyperbranched structure and terminal thiocarbonyl groups is demonstrated. Its hydrogen bonding network exhibits remarkable moisture resistance enables complete fast healing at room temperature.
Gas breakdown is typically driven by Townsend avalanche and predicted mathematically Paschen’s law (PL). deviates from PL at microscale due to field emission, which depends critically on electrode condition; however, understanding of the impact initial surface roughness multiple events voltage incomplete. This paper assesses variation for a pin-to-plate setup in air atmospheric pressure gap distances 1 ± 0.5 μm, 5 10 μm with different roughnesses. Breakdown generally increases increasing...
Abstract Objectives This study aimed to identify novel targets in the carcinogenesis, therapy and prognosis of osteosarcoma from genomic level, together with screening ideal lead compounds potential inhibition regarding MMP-9. Methods Gene expression profiles GSE12865, GSE14359, GSE33382, GSE36001 GSE99671 were obtained respectively GEO database. Differentially expressed genes identified, functional enrichment analysis, such as GO, KEGG, GSEA, PPI performed make a comprehensive understanding...
Mushroom cultivation is a sustainable agricultural waste utilization method, but the lack of high-value produced spent mushroom substrate (SMS) has hindered development cultivation-based circular systems. Conversion and SMS via Protaetia brevitarsis larvae (PBL) have proven to be AASMS strategy. However, Auricularia auricula (AASMS), which contains woodchips, less palatable digestible for PBL. To solve this problem, in investigation, we screened out microflora (MF) fermentation by comparing...