A5100368559- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Lipid metabolism and disorders
- Circular RNAs in diseases
- Pancreatitis Pathology and Treatment
- Ferroptosis and cancer prognosis
- Diabetes and associated disorders
- Sarcoma Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- MicroRNA in disease regulation
- Nutrition, Genetics, and Disease
Xinjiang Academy of Agricultural and Reclamation Science
2023
Second Xiangya Hospital of Central South University
2023
Central South University
2023
University of South China
2022
Zhongda Hospital Southeast University
2021-2022
Diabetic nephropathy (DN) is one of the most common microvascular complications in diabetic patients, and main cause end-stage renal disease. The exact molecular mechanism DN not fully understood. aim this study was to identify novel biomarkers mechanisms for disease progression by weighted gene co-expression network analysis (WGCNA). From GSE142153 dataset based on peripheral blood monouclear cells (PBMC) DN, we identified 234 genes through WGCNA differential expression analysis. Gene...
Diabetes of the exocrine pancreas (DEP), also commonly described as pancreatogenic diabetes mellitus, is a type secondary to abnormalities in pancreatic or secretion pancreas. However, its pathogenesis not yet known. The aim this article was explore biomarkers DEP and their potential molecular mechanisms. Based on GSE76896 dataset, which acquired from Gene Expression Omnibus (GEO), we identified 373 genes by weighted gene co-expression network analysis (WGCNA) differential expression...
Objectives: Osteosarcoma is the most common primary malignant tumor in children and adolescents, 5-year survival of osteosarcoma patients gained no substantial improvement over past decades. Effective biomarkers diagnosing are warranted to be developed. This study aims explore novel correlated with immune cell infiltration development diagnosis osteosarcoma. Methods: Three datasets (GSE19276, GSE36001, GSE126209) comprising samples were extracted from Gene Expression Omnibus (GEO) database...
Abstract Background The CELF gene family is a set of highly conserved genes that encode RNA-binding proteins in human tissues and participate posttranscriptional modifications. has been reported to be associated with variety cancers, including lung cancer, liver cancer colorectal cancer. However, the expression, function clinical relevance members glioma remain uncertain because lack relevant studies. Materials & methods Bioinformatics analysis was used determine prognostic value immune...