Weiming Li

ORCID: 0000-0001-9220-514X
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About
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Research Areas
  • Pelvic and Acetabular Injuries
  • Appendicitis Diagnosis and Management
  • Hernia repair and management
  • Enhanced Recovery After Surgery
  • Nutrition and Health in Aging
  • Global Health Workforce Issues
  • Venous Thromboembolism Diagnosis and Management
  • Gastroesophageal reflux and treatments
  • Cancer-related molecular mechanisms research
  • Abdominal vascular conditions and treatments
  • Abdominal Surgery and Complications
  • Cancer, Hypoxia, and Metabolism
  • Gastrointestinal Tumor Research and Treatment
  • Plant Physiology and Cultivation Studies
  • Pancreatic and Hepatic Oncology Research
  • Renal function and acid-base balance
  • Clinical Nutrition and Gastroenterology
  • Eicosanoids and Hypertension Pharmacology
  • Extracellular vesicles in disease
  • Child Nutrition and Water Access
  • Nursing education and management
  • Medical Research and Treatments
  • Postharvest Quality and Shelf Life Management
  • Dermatologic Treatments and Research
  • Stress and Burnout Research

Army Medical University
2025

Chongqing Medical University
2025

Second Affiliated Hospital of Chongqing Medical University
2025

Dalian Medical University
2025

Kunming Medical University
2015-2024

Chinese Academy of Tropical Agricultural Sciences
2013-2024

South Subtropical Crops Research Institute
2013-2024

Minzu University of China
2024

Fuzhou Second Hospital
2022

Xiamen University
2022

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protease that regulates low density lipoprotein receptor (LDLR) protein levels. The mechanisms of this action, however, remain to be defined. We show here recombinant human PCSK9 expressed in HEK293 cells was readily secreted into the medium, with prosegment associated C-terminal domain. Secreted mediated cell surface LDLR degradation concentration- and time-dependent manner when added cells. Accordingly, cellular LDL uptake...

10.1194/jlr.m700071-jlr200 article EN cc-by Journal of Lipid Research 2007-04-21

Numerous studies have investigated the utility of serum intestinal fatty-acid binding protein (I-FABP) in differentiating acute ischemia from abdomen. However, results remain controversial. The aim this meta-analysis is to determine overall accuracy I-FABP diagnosis ischemia. Publications addressing ischemic bowel diseases were selected databases. values true-positive (TP), true-negative (TN), false-positive (FP), and false-negative (FN) extracted or calculated for each study. Pooled...

10.1038/srep34371 article EN cc-by Scientific Reports 2016-09-29

The effects of preoperative oral administration glucose solution combined with postoperative probiotics on inflammation and intestinal barrier function in patients after colorectal cancer surgery were observed. Sixty treated scheduled to undergo radical resection Second Affiliated Hospital Kunming Medical University from March 2017 December selected randomly divided into the group (n=30) (n=30). Patients both groups took orally 12.5% before surgery, those received bifidus-triple viable...

10.3892/ol.2019.10336 article EN Oncology Letters 2019-05-08

The aim of this prospective study was to screen and combine effective biomarkers improve their diagnostic performance in detecting intestinal barrier dysfunction patients after major abdominal surgery.Patients undergoing surgery were enrolled signing informed consent study. serum concentrations α-GST, DAO, D-lactate, citrulline I-FABP detected 24 hours before surgery. five on assessed using logistic regression models receiver operating characteristic (ROC) curve analyses.Thirty-nine with...

10.21037/atm.2019.07.102 article EN Annals of Translational Medicine 2019-08-01

Eleven mango cultivars which were cultivated popularly in China selected as materials this study. The ascorbic acid, α-tocopherol, total carotenoid, ployphenol, flavonoid, and mangiferin contents, vitro antioxidant capability of the fruit pulp tested for comparison individual cultivars. Comparisons parameters further conducted after dividing all into three groups, i.e., red (Zill, Zillate, Renong No. 2, Keitt Lippens), green (Guire 82, Yuexi 1 Zihua) yellow (Chunhuang, Tainong 1) peel color....

10.1080/10942912.2012.687798 article EN International Journal of Food Properties 2013-08-25

Hepatocellular carcinoma (HCC) is a highly vascular tumor, and treatment options for patients of advanced-stage are limited. Nitric oxide (NO), which derived from endothelial nitric synthase (eNOS), provides crucial signals angiogenesis in the tumor microenvironment. Tetrahydrobiopterin (BH4) an essential cofactor eNOS represents critical determinant NO production. To examine whether 2,4-diamino-6-hydroxypyrimidine (DAHP) inhibits HCC, BALB/c-nu mice were injected with HepG-2 cells DAHP....

10.3892/or.2016.4850 article EN cc-by-nc-nd Oncology Reports 2016-06-02

To investigate the impact of nutritional support on clinical outcomes in patients at risk who receive that meets guideline standards and those do not. This prospective cohort study enrolled hospitalized from Second Affiliated Hospital Kunming Medical University February 2010 to June 2012. The research protocols were approved by university's ethics committee, signed informed consent forms. data collected based screening, administration enteral parenteral nutrition, surgical information,...

10.1186/s12937-016-0193-6 article EN cc-by Nutrition Journal 2015-12-01

Abstract Objective This paper aims to clarify the concept of occupational burnout (OB) as well develop appropriate methods relieve or prevent OB in nursing profession. Methods Walker and Avant’s eight-step approach analysis was applied. Results defined a chronic form work-related stress. Accurately, it characterized by emotional exhaustion, depersonalization/cynicism, reduced personal accomplishment/inefficacy. Antecedents included (a) demographic characteristics; (b) exposure stressors; (c)...

10.2478/fon-2020-0006 article EN cc-by Frontiers of Nursing 2020-03-01

Because of their tolerance to root rot and many abiotic stresses, rootstocks are generally required for commercial avocado production. However, cutting air-layering, which popular methods vegetative propagation producing large numbers uniform genetically identical plants, have been unsuccessful years. To develop a practical efficient rooting procedure selected clonal rootstocks, the present research investigated effects various factors on cutting. Shoots were divided into three groups (air...

10.3390/horticulturae10070770 article EN cc-by Horticulturae 2024-07-21

The incidence of ultrasound seromas has significantly increased after large hernial sac surgery. Several methods are available for preventing seromas, but the clinical results poor. It also been demonstrated that stump fenestration during laparoscopic incisional hernia repair surgery can decrease seromas.Ninety patients aged 18-75 years who were treated in our hospital primary Type III indirect inguinal from March 2017 to 2018 randomised a preventive group and control group. All underwent...

10.4103/jmas.jmas_185_20 article EN cc-by-nc-sa Journal of Minimal Access Surgery 2021-02-03

Objective: To investigate the effect and mechanism of tetrahydrobiopterin (BH4) on angiogenesis in hepatocellular carcinoma (HCC). Methods: BALB/c-nu mice were subcutaneously injected with HepG-2 cells randomly divided into control BH4 groups. The group received 20 mg/kg or saline by intraperitoneal injection daily for two weeks, respectively. level was measured high performance liquid chromatography (HPLC), nitric oxide (NO) Griess test array, transcriptional K-ras quantitative RT-PCR,...

10.3760/cma.j.issn.0253-3766.2016.11.002 article EN PubMed 2016-11-23
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