A5090709606- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Reproductive Physiology in Livestock
- Amyotrophic Lateral Sclerosis Research
- Animal Genetics and Reproduction
- Toxoplasma gondii Research Studies
- Reproductive biology and impacts on aquatic species
- Parasitic Infections and Diagnostics
- Cholinesterase and Neurodegenerative Diseases
- Hormonal and reproductive studies
- T-cell and Retrovirus Studies
- Veterinary Equine Medical Research
- Vector-Borne Animal Diseases
- Biochemical Acid Research Studies
- Pineapple and bromelain studies
- Aquaculture Nutrition and Growth
- Agricultural and Food Sciences
- Dental Research and COVID-19
- Sarcoma Diagnosis and Treatment
- Viral Infectious Diseases and Gene Expression in Insects
- Soft tissue tumor case studies
- Bee Products Chemical Analysis
- Autoimmune Neurological Disorders and Treatments
- Social Media in Health Education
- Healthcare Regulation
Centro Hospitalar de Lisboa Central
2025
Hospital de Santo António
2025
Universidade Estadual Paulista (Unesp)
2015-2022
Universidade de São Paulo
2010-2022
University of Coimbra
2020-2022
Universidade Estadual de Goiás
2018
Universidade Federal de Minas Gerais
2016
Alzheimer’s disease (AD) is the most common form of dementia worldwide, being characterized by deposition senile plaques, neurofibrillary tangles (enriched in amyloid beta (Aβ) peptide and hyperphosphorylated tau (p-tau), respectively) memory loss. Aging, type 2 diabetes (T2D) female sex (especially after menopause) are risk factors for AD, but their crosslinking mechanisms remain unclear. Most clinical trials targeting AD neuropathology failed it remains incurable. However, evidence...
Anti-N-methyl-D-aspartate (NMDA) receptor (NMDAR) encephalitis is a relatively recent condition, classified as an immune-mediated disorder characterized by complex neuropsychiatric syndrome and the presence of anti-GluN1 subunit antibodies against NMDA in cerebrospinal fluid (CSF). Although it rare disease, studies have identified one most common causes autoimmune encephalitis. The pathophysiology this condition not yet fully understood, especially regarding its association with ovarian...
This is the case of a patient who went to emergency department with back pain and constitutional symptoms (weight loss, anorexia, nausea) lasting one month. Blood tests revealed hypercalcemia new-onset kidney failure that prompted admission for study. Bone X-ray multiple lytic lesions, myeloma screening was negative. After bone marrow biopsy guided by ultrasound lesion, it possible obtain diagnosis diffuse large B-cell lymphoma. We present this diagnostic challenge atypical presentation...
Heat shock during sperm capacitation affects the spermatozoa quality, resulting in increased early acrosome reaction and consequently decreasing their fertilizing capacity. Although mechanisms involved regulation of are not fully understood, it has been reported that Ca2+/calmodulin-dependent protein kinase II (CaMKII) is an important regulator these processes. Thus, present aimed to evaluate effect heat CaMKII signaling bovine acrosome. Bovine were vitro capacitated for 4 hours. The was...
The industry has made available in the market a series of substances (nutraceuticals) which intent would be to optimize use nutrients some metabolic paths, influencing positively reproductive performance animals. However, response nutraceuticals varies according animal. As organism is highly complex and order achieve perfect activity hypothalamic-pituitary-gonadal axis, an ideal interaction molecular basis needed, where can have their direct action. aim this study was review function...
Elevated temperatures disturbed sperm physiology. Bovine cells exposed to heat shock led diminished mitochondrial activity, fertilizing ability, increased oxidative stress and caspase activity concomitant with a delay in embryonic developmental kinetics modulation of sperm-borne microRNAsmiRNAs.Sperm function is susceptible adverse environmental conditions. It has been demonstrated that vivo vitro exposure bovine elevated temperature reduces motility potential. However, the cascade...
Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal and rapidly progressing neurodegenerative disease that affects motor neurons. This associated with oxidative stress especially in mutant superoxide dismutase 1 (mutSOD1) patients. However, less known for the most prevalent sporadic ALS form, due to lack of models. Here, we studied profiles lymphoblasts from patients mutSOD1 or unknown (undSOD1) mutations. Methods undSOD1 lymphoblasts, as well sex/age‐matched controls...
Integrated farming is an established agricultural practice aimed at increasing productivity per unit area by utilizing animal manure. However, there has been a growing concern regarding swine manure's potential as disseminator of pathogens in the environment. Among these Porcine Circovirus 2 (PCV2), which can persist environment for extended periods. The objective this study to demonstrate impact introducing two PCV2 vaccination protocols on load faecal samples and surrounding To achieve...
A informação correta é determinante na qualidade do uso de medicamentos e tomada decisões em saúde. Assim, fundamental a formação profissionais capazes interpretar evidência científica sobre medicamentos, transformando-a fácil acesso. Nesse sentido, o Centro Estudos Medicamento (CEMED) da Faculdade Farmácia Universidade Federal Minas Gerais (UFMG) promove voltada para racional utilizando divulgação informações por meio weblog (Blog CEMED). publicação no depende papel ativo dos discentes, os...
Abstract Amyotrophic lateral sclerosis (ALS) is a fatal and rapidly progressing neurodegenerative disease that affects motor neurons. This associated with oxidative stress especially in mutant superoxide dismutase 1 (mutSOD1) patients. However, less known for the most prevalent sporadic ALS due to lack of models. Here, we studied profiles lymphoblasts from patients mutSOD1 or unknown (undSOD1) mutations. undSOD1 lymphoblasts, as well sex/age-matched controls (3/group) were obtained Coriell...