A5083060057- Attention Deficit Hyperactivity Disorder
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Muscle Physiology and Disorders
- Radiomics and Machine Learning in Medical Imaging
- Fetal and Pediatric Neurological Disorders
- Cerebral Palsy and Movement Disorders
- Pediatric Urology and Nephrology Studies
- Transcranial Magnetic Stimulation Studies
- Glioma Diagnosis and Treatment
- Brain Tumor Detection and Classification
- Nutrition and Health in Aging
- MRI in cancer diagnosis
- RNA Research and Splicing
- Advanced Neuroimaging Techniques and Applications
- Adipose Tissue and Metabolism
- EEG and Brain-Computer Interfaces
- Photoreceptor and optogenetics research
Shenzhen Children's Hospital
2014-2025
Shantou University
2025
Shantou University Medical College
2025
Abstract Objectives Duchenne muscular dystrophy (DMD) and Becker (BMD) present similar symptoms in the early stage, complicating their differentiation. This study aims to develop a classification model using radiomic features from MRI T2-weighted Dixon sequences increase accuracy of distinguishing DMD BMD disease stage. Methods We retrospectively analysed data 62 patients aged 36–60 months with dystrophy, including 41 21 BMD. Radiomic were extracted in-phase, opposed-phase, water, fat,...
Objective: This study investigates whether the dynamic functional connectivity (dFC) of amygdala subregions is altered in children with attention-deficit/hyperactivity disorder (ADHD). Methods: The dFC was systematically calculated using a sliding time window method, for 75 ADHD and 20 healthy control (HC) children. Results: Compared HC group, right superficial exhibited significantly higher prefrontal cortex, left precuneus, post-central gyrus group. showed negative association cognitive...
Anomalies in large-scale cognitive control networks impacting social attention abilities are hypothesized to be the cause of deficit hyperactivity disorder (ADHD). The precise nature abnormal brain functional connectivity (FC) dynamics including other regions, on hand, is unknown. concept that insular dynamic FC (dFC) among distinct regions dysregulated children with ADHD was evaluated using Insular subregions, and we studied how these dysregulations lead dysfunctioning. Data from 30 28...
The aim was to investigate the relationship between apparent diffusion coefficient (ADC) values measured by diffusion-weighted magnetic resonance imaging (DW MRI) and split glomerular filtration rate (GFR) in infants with congenital hydronephrosis. Diffusion-weighted (DWI) (b = 0 700 seconds/mm2) performed a General Electric Company (GE) Signa 1.5T MR unit 46 suffering single hydronephrosis 30 healthy as normal control group. ADCs were calculated regions of interest (ROIs) positioned renal...
OBJECTIVE. The purpose of this study was to investigate the potential high-speed T2-corrected multiecho (HISTO) MR spectroscopy (MRS) for rapidly quantifying fat content thigh muscles in children with Duchenne muscular dystrophy (DMD). SUBJECTS AND METHODS. This prospectively enrolled 58 boys DMD (mean age, 7.5 years; range, 4-11 years) and 30 age-matched healthy 7.2 at one institution over a 1-year period. T1- T2-weighted, Dixon, HISTO sequences were performed on right adductor magnus...
Objective: The present study aimed to investigate the effects of dopamine receptor D4 (DRD4) -521 C/T single-nucleotide polymorphism on brain function among children with attention deficit hyperactivity disorder (ADHD) and evaluate whether is associated behavioral performance this demographic. Methods: Using regional homogeneity, fractional amplitude low-frequency fluctuation, functional connectivity as measurement indices, we compared differences in resting-state between 34 boys ADHD TT...
Objective: The present study aimed to examine the effects of SNAP25 on integration ability intrinsic brain functions in children with ADHD, and whether was associated working memory (WM). Methods: A sliding time window method used calculate spatial temporal concordance among five rs-fMRI regional indices 55 ADHD 20 healthy controls. Results: exhibited significant interaction diagnosis voxel-wise right posterior central gyrus, fusiform gyrus lingual gyrus. Specifically, for G-carriers showed...
Abstract Introduction Attention deficit/hyperactivity disorder (ADHD) is a hereditary neurodevelopmental characterized by working memory (WM) deficits. The Mnl I variant (rs3746544) of the synaptosomal‐associated protein 25 (SNAP‐25) gene associated with ADHD. In this study, we investigated role and underlying mechanism SNAP‐25 in cognitive impairment brain functions boys Method We performed WM capacity tests using fourth version Wechsler Intelligence Scale for Children (WISC‐IV) regional...
Attention-deficit/hyperactivity disorder (ADHD) is one of the most widespread and highly heritable neurodevelopmental disorders affecting children worldwide. Although synaptosomal-associated protein 25 (SNAP-25) a possible gene hypothesized to be associated with working memory deficits in ADHD, little known about its specific impact on hippocampus. The goal current study was determine how variations ADHD's SNAP-25 Mnll polymorphism (rs3746544) affect hippocampal functional connectivity...
Infantile epileptic spasms syndrome (IESS) would accompany with severe neurological impairment. Our study aimed to explore the potential mechanism by employing voxel-based and surface-based morphometry detect brain microwould microanatomic structure alteration.