A5033945084- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Sarcoma Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- Spine and Intervertebral Disc Pathology
- Liver Disease and Transplantation
- Advanced X-ray and CT Imaging
- Medical Imaging and Analysis
- Musculoskeletal pain and rehabilitation
- Pediatric Hepatobiliary Diseases and Treatments
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- Bone Tumor Diagnosis and Treatments
- Gallbladder and Bile Duct Disorders
- Renal and Vascular Pathologies
- Anatomy and Medical Technology
- Facial Nerve Paralysis Treatment and Research
- Genetic and Kidney Cyst Diseases
- RNA modifications and cancer
- Botulinum Toxin and Related Neurological Disorders
- AI in cancer detection
Zhujiang Hospital
2015-2024
Southern Medical University
2015-2024
Guangdong Academy of Medical Sciences
2024
Guangdong Provincial People's Hospital
2024
Jinan University
2013
Abstract Diffusion‐derived vessel density (DVDD) is a physiological surrogate of the area microvessels per unit tissue area. DDVD calculated according to DDVD(b0b2) = Sb0/ROIarea0 – Sb2/ROIarea2, where Sb0 and Sb2 refer liver signal when b 0 or 2 s/mm . Pathohistological studies contrast‐enhanced CT/MRI data showed higher blood volume in hepatocellular carcinoma (HCC) relative native tissue. With intravoxel incoherent motion (IVIM) imaging, most authors paradoxically reported decreased...
The accurate prediction of post-hepatectomy early recurrence in patients with hepatocellular carcinoma (HCC) is crucial for decision-making regarding postoperative adjuvant treatment and monitoring. We aimed to explore the feasibility deep learning (DL) features derived from gadoxetate disodium (Gd-EOB-DTPA) MRI, qualitative features, clinical variables predicting recurrence.In this bicentric study, 285 HCC who underwent Gd-EOB-DTPA MRI before resection were divided into training (n = 195)...
Objectives To develop and validate a nomogram to detect improved knee pain in osteoarthritis (OA) by integrating magnetic resonance imaging (MRI) radiomics signature of subchondral bone clinical characteristics. Methods Participants were selected from the Vitamin D Effects on Osteoarthritis (VIDEO) study. The primary outcome was 20% improvement score over 2 years participants administrated either vitamin or placebo. Radiomics features characteristics 216 extracted analyzed. randomly split...
Using the amplitude of low-frequency fluctuation (ALFF) and functional connectivity (FC) algorithm to study alteration brain function in hemodialysis patients with end-stage renal disease (ESRD).We recruited 20 ESRD on regular 17 healthy controls (HCs). All participants underwent resting-state fMRI (rs-fMRI), neuropsychological tests, blood biochemical examination. The individual ALFF values between two groups were tested by an independent sample t-test. Then, we set altered areas as seed...
Liver hemangiomas (HGs) are characterized by cavernous venous spaces delineated a lining of vascular endothelial cells and interspersed with connective tissue septa. Typically, liver HG has higher apparent diffusion coefficient (ADC) T2 values than those hepatocellular carcinomas (HCCs) metastases, lower ADC simple cysts. However, portion HGs shows overlapping HCC, metastasis, cyst. When MRI is the first line examination for liver, contrast enhanced imaging commonly used to confirm diagnosis...
Purpose To explore the characteristics of intravoxel incoherent motion (IVIM) in various stages liver fibrosis, and their relationships with fibrotic rats. Materials Methods Fifty rats were given doses carbon tetrachloride (CCl4) to induce rats; 15 untreated served as controls. Diffusion-weighted magnetic resonance imaging (MRI) was performed eight b-values (0–800 s/mm2) applied obtain IVIM parameters (D, pure molecular diffusion; f, perfusion fraction; D*, pseudodiffusion). The fibrosis...
To explore the value of T1 relaxation times in rotating frame (T1 ρ or rho) for evaluating liver fibrosis stage, compared to apparent diffusion coefficients (ADCs).Liver model rats (n = 50) was produced by carbon tetrachloride (CCl4 ) injection. Five died during experiment. Surviving 45) and controls 15) were subjected 3.0T MRI ADCs (b-values: 0, 800 s/mm(2) values determined. Liver stage (F0-F4) defined based on METAVIR scoring. Nonparametric statistical methods receiver operating...
Background and Objective: Idiopathic central precocious puberty (ICPP) is characterized by early pubertal changes, the acceleration of growth velocity, rapid bone maturation that often results in reduced adult height. Gonadotrophin-releasing hormone agonist (GnRHa) currently considered to be an effective therapeutic agent. At present, GnRH stimulation test adopted as a gold standard for diagnosis ICPP efficacy evaluation GnRHa therapy. However, it difficult operate practice due cumbersome...
Objective. To develop and externally validate a CT-based radiomics nomogram for pretreatment prediction of relapse in osteosarcoma patients within one year. Materials Methods. In this multicenter retrospective study, total 80 (training cohort: 63 from three hospitals; validation 17 other hospitals) with osteosarcoma, undergoing CT between August 2010 December 2018, were identified databases. Radiomics features extracted selected tumor regions on image, then, the signature was constructed....
Background: Although postoperative adjuvant transarterial chemoembolization (PA-TACE) improves survival outcomes in a subset of patients with resected hepatocellular carcinoma (HCC), the lack reliable biomarkers for patient selection remains significant challenge. The present study aimed to evaluate whether computed tomography (CT) imaging can provide more value predicting benefits from PA-TACE and establish new scheme guiding benefits. Methods: In this retrospective study, HCC who had...
For liver intravoxel incoherent motion (IVIM) data acquisition, respiratory‐triggering (RT) MRI is commonly used, and there are strong motivations to shorten the scan duration. same duration, more b values or higher numbers of excitations can be allowed for free‐breathing (FB) imaging than RT. We studied whether FB used replace RT when careful IVIM image acquisition processing conducted. 22 healthy participants were acquired using a 3.0 T scanner. Diffusion was based on single‐shot...
Renal fibrosis is a common consequence of chronic kidney disease (CKD) and the mechanism by which various forms CKD progress to endstage renal failure. Accurate assessment important for treatment.To measure longitudinal changes intravoxel incoherent motion (IVIM) arterial spin labeling (ASL) before after reversible unilateral ureteral obstruction in an animal model.Self-controlled study.Surgical ureters was performed then removed 5 days. Rats were scanned on Days 0, 1, 3, creating 4, 7, 12...
Early diagnosis of liver fibrosis is important. The objective this study was to explore the characteristics and assess accuracy monoexponential, stretched exponential models (SEM), diffusion kurtosis imaging (DKI) with diffusion-weighted (DWI)-magnetic resonance (MRI) in various stages two standard rat induced by carbon tetrachloride (CCl4) biliary duct ligation (BDL). Parameters (ADC, Dapp, Kapp, DDC, α) were measured a 3.0T MRI. Liver (F0-F4) defined METAVIR scoring. DDC) found be...
Evaluation of Mesorectal Microcirculation With Quantitative Dynamic Contrast-Enhanced MRIXinyue Yang1, Yiyan Liu2, Yan Chen2, Ziqiang Wen2, Bomiao Lin1, Xianyue Quan1 and Shenping Yu2Audio Available | Share
The present study investigated the application of T1ρ and T2 relaxation mapping magnetic resonance imaging (MRI) diffusion-weighted (DWI) in evaluation intervertebral disc degeneration (IDD). A total 93 asymptomatic subjects were imaged with mapping, as well DWI. Pfirrmann grading was performed correlation analysis conducted for T1ρ, DWI results age. indicated 69 cases grade I, 240 II, 101 III, 43 IV 12 V. MRI showed that values nucleus pulposi at L4/5 L5/S1 significantly reduced (P<0.05) no...
Abstract Objective The aim of this study was to investigate placental blood perfusion in middle and late pregnancy explore its predictive value for fetal growth restriction (FGR). Methods All pregnant women included the were examined using intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI). Three IVIM parameters (D, f, D*) obtained each woman analyzed Image J software. Perfusion fraction f is a radiological marker perfusion. pulsatility index (PI) uterine artery used...
Objective This study was performed to assess the changes in diameter of superior mesenteric artery (SMA) patients with spontaneous isolated SMA dissection (SISMAD) on nonenhanced multidetector computed tomography (MDCT) and determine clinical value follow-up MDCT after endovascular stent placement (ESP). Methods The diameters vein (SMV) as measured were compared between 20 SISMAD control subjects. ESP 14 SISMAD, ESP. Results mean group 11.69 ± 1.26 7.10 0.97 mm, respectively, a statistically...
Purpose: To develop and further validate a deep learning signature-based nomogram from computed tomography (CT) images for prediction of the overall survival (OS) in resected non-small cell lung cancer (NSCLC) patients. Patients Methods: A total 1792 features were extracted non-enhanced venous-phase CT each NSCLC patient training cohort (n=231). Then, signature was built with least absolute shrinkage selection operator (LASSO) Cox regression model OS estimation. At last, constructed other...