A5078343433- Epilepsy research and treatment
- Neuroscience and Neuropharmacology Research
- Glioma Diagnosis and Treatment
- EEG and Brain-Computer Interfaces
- Facial Nerve Paralysis Treatment and Research
- MicroRNA in disease regulation
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
- Circular RNAs in diseases
- Head and Neck Surgical Oncology
- Neuroscience and Neural Engineering
- Memory and Neural Mechanisms
- Meningioma and schwannoma management
- Cancer-related molecular mechanisms research
- Neural dynamics and brain function
- FOXO transcription factor regulation
- Neurological disorders and treatments
- Cancer Mechanisms and Therapy
Southern Medical University
2017-2023
Zhujiang Hospital
2017-2023
Parkinson's disease (PD) is a pervasive neurodegenerative disease, and levodopa (L-dopa) its preferred treatment. The pathophysiological mechanism of levodopa-induced dyskinesia (LID), the most common complication long-term L-dopa administration, remains obscure. Accumulated evidence suggests that dopaminergic as well non-dopaminergic systems contribute to LID development. As 5-hydroxytryptamine 1A/1B receptor agonist, eltoprazine ameliorates dyskinesia, although little known about...
Medulloblastoma (MB) is the most frequent malignant brain tumor in pediatrics. Since current standard of care for MB consisting surgery, cranio‑spinal irradiation and chemotherapy often leads to a high morbidity rate, number patients suffer from long‑term sequelae following treatment. Targeted therapies hold promise being more effective less toxic. Therefore, present study aimed identify hub genes with an upregulated expression search potential therapeutic targets these genes. For this...
The aim of this study is to identify the factors predicting persistent hydrocephalus after periventricular tumor resection in children and assess need efficacy perioperative cerebrospinal fluid (CSF) intervention. We performed a retrospective analysis pediatric patients who underwent surgery between March 2012 July 2021 at Department Neurosurgery Zhujiang Hospital South Medical University. Demographic, radiographic, perioperative, dispositional data were analyzed using univariate...
Objective To describe a rhesus monkey model of temporal lobe epilepsy (TLE) established via repetitive unilateral intra-amygdala kainic acid (KA) injection and provide experimental basis for epileptogenic network related research. Methods Eight male adult monkeys were randomly divided into KA group (n=6) saline (n=2). Brain stereotaxic technique, micro catheter implantation the right amygdaloid nucleus, subcutaneous bladder connection, continuous video-EEG monitoring performed, or...