Objectives To evaluate the feasibility of utilizing cardiac computer tomography (CT) images for extracting radiomic features myocardium at junction between left atrial appendage (LAA) and atrium (LA) in patients with fibrillation (AF) to its asscociation risk AF. Methods A retrospective analysis was conducted on 82 cases AF 56 control group who underwent CT our hospital from May 2022 2023, recorded clinical information. The morphological parameters LAA were measured. radiomics model, a...

Numerous bacterial pathogens have evolved tactics to interfere with the host ubiquitination network evade clearance by innate immune system. Nevertheless, subtle antagonism between a ubiquitinase and deubiquitinase, through which they modify their respective targets within multifaceted network, has yet be characterized. BRCC3 isopeptidase complex (BRISC) is newly identified K63-specific deubiquitinase that plays crucial role in cellular signaling pathways such as inflammation. NleG, type III...

Liver hemangiomas (HGs) are characterized by cavernous venous spaces delineated a lining of vascular endothelial cells and interspersed with connective tissue septa. Typically, liver HG has higher apparent diffusion coefficient (ADC) T2 values than those hepatocellular carcinomas (HCCs) metastases, lower ADC simple cysts. However, portion HGs shows overlapping HCC, metastasis, cyst. When MRI is the first line examination for liver, contrast enhanced imaging commonly used to confirm diagnosis...

Neuroimaging is a cornerstone in the diagnosis and treatment decision-making for brain acute ischemic stroke. A rapid accurate key, specifically time-critical reperfusion therapies. Successful of salvageable penumbra can reduce extent stroke thus improve clinical outcomes, whereas irreversibly affected tissue thought to be futile may result harm due risk hemorrhagic transformation. For neuroimaging work-up stroke, computed tomography (CT) more commonly applied than magnetic resonance imaging...

Streptococcus suis infection represents a major challenge in pig farming and public health due to its zoonotic potential diverse serotypes, while existing vaccines lack effective cross-protection. This study employed reverse vaccinology immunoinformatics identify 8 conserved proteins across 11 prevalent serotypes of S. suis. 16 candidate epitopes were selected design three multi-epitope antigens against (designated as MEASs), which fused with dendritic cell-targeting peptide improve antigen...

Abstract This study was to quantitatively investigate the role of morphological and functional parameters left atrium (LA) atrial appendage (LAA) with 256-slice spiral computed tomography (CT) in recurrence fibrillation (AF) after radiofrequency ablation (RFA). Eighty-three patients AF who underwent RFA for first time were divided into (n = 27) non-recurrence 56) groups. All a CT examination before operation. The clinical data quantitative measurement morphology LA LAA analyzed, including...

Objective To investigate quantitatively the morphology, anatomy and function of left atrial appendage (LAA) its relation with adjacent structures. Materials Methods A total 860 patients (533 men, 62.0%, age 55.9±10.4 year) who had cardiac multidetector computed tomography angiography from May to October 2012 were enrolled for analysis. Results Seven types 6 subtypes LAA morphology found Type 2 being most prevalent. 5 was more significantly (P<0.05) present in women (8.0%) than men (4.2%)....

Diffusion-derived 'vessel density' (DDVD) is a surrogate of the area micro-vessels per unit tissue. DDVD calculated according to: (b0b50) = Sb0/ROIarea0 - Sb50/ROIarea50, where Sb0 and Sb50 refer to tissue signal when b 0 or 50 s/mm2. Due complexity pre-eclampsia (PE), even combination risk factors available tests cannot accurately diagnose predict PE. This study applies assess perfusion placenta, placenta disturbance in PE patients. Diffusion-weighted images with b-values 0, s/mm2 were...

The present study evaluated the value of black-blood high-resolution magnetic resonance imaging (HRMRI) for visualization intracranial atherosclerosis (ICAS) plaques. A total 110 patients with cerebral artery or vertebrobasilar stenosis, vessel occlusion a significantly weakened signal in angiography (MRA; three-dimensional time-of-flight) were examined. Black-blood MRA was used to observe whether plaques abnormal vascular walls. Among infarction, 16 cases presented no significant...

Background: The significance of the right atrial appendage (RAA) and atrium (RA) in recurrence fibrillation (AF) after radiofrequency ablation (RFA) remains uncertain. This retrospective case-control study aimed to quantitatively evaluate role morphological parameters RAA RA AF RFA based on 256-slice spiral computed tomography (CT). Methods: A total 297 patients with who underwent for first time between January 1 October 31, 2020, were enrolled study, they divided into a nonrecurrence group...

To investigate the value of parameters pulmonary artery and right ventricular function in predicting 30-day poor prognosis patients with acute embolism (APE). The heart rate, respiratory systolic blood pressure, Wells score for APE, history recent operation or immobilization, cancer, failure, smoking were significantly ( P &lt; .05) different among control, good prognosis, groups. maximal short diameter left ventricle (RVD/LVD) ratio .001) (LPA) = .01) between Systolic pressure (odds [OR]:...

We performed this cohort study to investigate whether the myocardial bridge (MB) affects fat attenuation index (FAI) and determine optimal cardiac phase measure volume FAI of pericoronary adipose tissue (PCAT). The data 300 patients who were diagnosed with MB left anterior descending (LAD) coronary artery retrospectively analyzed. All divided into group atherosclerosis group. In addition, 104 negative CCTA results enrolled as control There was no significant difference between values...

As an integral part of the left atrium (LA), atrial appendage (LAA) plays important role in fibrillation (AF). However, relationship between LAA remodeling and AF has not been clearly defined. This retrospective case-control study aimed to assess morphological functional features LA patients using images obtained by computed tomography angiography (CTA).A total 140 64 without or other cardiovascular diseases who underwent CTA scans September 2016 August 2017 were enrolled this observational...

To quantitatively investigate left ventricular volume and function in middle-aged healthy subjects.Ninety volunteers underwent cardiac 3 Tesla MRI. The end-diastolic (EDV) end-systolic (ESV), stroke (SV), ejection fraction (EF), output (CO), myocardial mass (MM), their normalized indices (EDVI, ESVI, SVI, CI, MI, respectively) after corrected with the body surface area (BSA) were analyzed compared at different ages.All subjects had successfully completed 3-Tesla MR. Females significantly...

The significance of left atrial appendage (LAA) filling defects on early-phase cardiac computed tomography (CCT) remains uncertain. This study retrospectively investigated predictive factors LAA CCT.A total 68 patients with nonvalvular fibrillation (AF) and early defect CCT who underwent transthoracic echocardiography (TTE) transesophageal (TEE) were enrolled [48 males, 20 females; mean ± standard deviation (SD) age 62.72±8.13 years]. Additionally sex- age-matched normal included as the...

This study investigated the correlation between 3-Tesla magnetic resonance imaging (MRI) and 256 multiple-slice computed tomography (MSCT) or 2-dimensional echocardiography (ECHO) in evaluating left ventricle. Forty patients were retrospectively enrolled to undergo cardiac MSCT, MRI ECHO within 1 week. The end-diastolic (EDV) end-systolic volume (ESV), stroke (SV) ejection fraction (EF) analyzed compared. MSCT was highly significantly correlated with MRI. Compared MRI, slightly overestimated...

Objective: To investigate the efficiency of spectral computed tomography (CT) optimal monochromatic images in improving imaging quality liver vessels. Materials and Methods:The data 35 patients with abdominal CT angiography were retrospectively analyzed.Hepatic arteries, portal veins, hepatic veins reconstructed mixed energy (quality check, QC), 70 keV mode.Comparative parameters analyzed including value, image noise (IN), contrast-to-noise ratio (CNR), signal-to-noise (SNR), subjective...

This study has investigated the effect of a potent bioflavonoid, troxerutin, on diabetes-induced changes in pro-inflammatory mediators and expression microRNA-146a nuclear factor-kappa-B (NF-κB) signaling pathway aortic tissue type-I diabetic rats. Male Wistar rats were randomly divided into four groups (n = 6/each): healthy, healthy-troxerutin, diabetic, diabetic-troxerutin. Diabetes was induced by streptozotocin injection (60 mg/kg; intraperitoneally) lasted 10 weeks. Troxerutin (150...

The purpose of the study was to evaluate relationship between computed tomography pulmonary angiography (CTPA) test bolus curve data and mortality in patients with embolism (PE) comparison conventional methods right ventricular (RV) dysfunction.The approved by our institutional review board is HIPAA-compliant. We retrospectively evaluated consecutive CTPA studies performed a technique 2-year period. A time-density derived from each bolus. For comparison, left (LV) RV dimensions (area,...