A5030177801- Municipal Solid Waste Management
- Streptococcal Infections and Treatments
- Escherichia coli research studies
- Inflammasome and immune disorders
- Construction Project Management and Performance
- Recycled Aggregate Concrete Performance
- Sustainable Building Design and Assessment
- Occupational Health and Safety Research
- Plant Pathogenic Bacteria Studies
- Software Engineering Techniques and Practices
- Viral Infections and Immunology Research
- Metalloenzymes and iron-sulfur proteins
- Recycling and Waste Management Techniques
- Respiratory viral infections research
- Advanced Memory and Neural Computing
- Toxin Mechanisms and Immunotoxins
- Risk and Safety Analysis
- BIM and Construction Integration
- Animal Virus Infections Studies
- Antibiotic Resistance in Bacteria
- Leptospirosis research and findings
- Neonatal and Maternal Infections
- Adenosine and Purinergic Signaling
- Sustainable Supply Chain Management
- Biomarkers in Disease Mechanisms
Nanjing Agricultural University
2020-2025
Tongji University
2024-2025
Shandong Jianzhu University
2021
Wuhan Center for Disease Control and Prevention
2021
Numerous bacterial pathogens have evolved tactics to interfere with the host ubiquitination network evade clearance by innate immune system. Nevertheless, subtle antagonism between a ubiquitinase and deubiquitinase, through which they modify their respective targets within multifaceted network, has yet be characterized. BRCC3 isopeptidase complex (BRISC) is newly identified K63-specific deubiquitinase that plays crucial role in cellular signaling pathways such as inflammation. NleG, type III...
Purpose Due to the flexibility and proactivity emphasized by job crafting in today’s uncertain complex era, scholars have preliminarily proved its positive consequences project context. Nevertheless, little is known about task-related antecedents of construction environment whether these task factors can be further converted into performance through teams, thereby motivating this study. Design/methodology/approach Drawing on person-environment fit theory, study hypothesized teams as a...
Objective Schizophrenia is a complex mental disorder that significantly impacts social functioning. The present study aimed to investigate the relationship between psychotic symptoms and functioning in individuals with chronic schizophrenia. Specifically, we examined mediating roles of avoidance impaired interpersonal trust this relationship, as these factors are most worrisome Methods A total 223 outpatients schizophrenia 201 unrelated healthy controls were included. Positive Negative...
As a respiratory tract virus, SARS-CoV-2 infected people through contacting with the upper first. Previous studies indicated that microbiota could modulate immune response against pathogen infection. In present study, we performed metagenomic sequencing of pharyngeal swabs from eleven patients COVID-19 and Non-COVID-19 who had similar symptoms such as fever cough. Through analysis above two groups healthy group public data, there are 6502 species identified in samples. Specifically, Pielou...
Streptococcus suis infection represents a major challenge in pig farming and public health due to its zoonotic potential diverse serotypes, while existing vaccines lack effective cross-protection. This study employed reverse vaccinology immunoinformatics identify 8 conserved proteins across 11 prevalent serotypes of S. suis. 16 candidate epitopes were selected design three multi-epitope antigens against (designated as MEASs), which fused with dendritic cell-targeting peptide improve antigen...
ABSTRACT Streptococcus suis is an important zoonotic pathogen, causing cytokine storms of Streptococcal toxic shock‐like syndrome amongst humans after a wound infection into the bloodstream. To overcome challenges fever and leukocyte recruitment, invasive S. must deploy multiple stress responses forming network utilize proteases to degrade short‐lived regulatory misfolded proteins induced by adverse stresses, thereby adapting evading host immune responses. In this study, we found that...
Extraintestinal pathogenic Escherichia coli (ExPEC) is one of the leading causes bloodstream infections in a broad spectrum birds and mammals, thus poses great threat to public health, while its underlying mechanism causing sepsis not fully understood. Here we reported high virulent ExPEC strain PU-1, which has robust ability colonize within host bloodstream, induced low level leukocytic activation. Two serine protease autotransporters Enterobacteriaceae (SPATEs), Vat PU-1 Tsh , were found...
Streptococcus suis serotype 2 (SS2) is a noteworthy zoonotic pathogen that has been responsible for large economic losses in pig production and great threat to human health. Pentraxin 3 (PTX3) an essential regulator of the innate immune response bacterial pathogens; however, its role during SS2 infection not fully understood. In this study, we found strain HA9801 induced significant inflammatory mouse air pouch model; was amplified by treatment exogenous PTX3 simultaneously terms results...
Apoptosis-enhancing nuclease (AEN), which shares close evolutionary relationships with the interferon-stimulated gene 20 protein (ISG20) homologs in humans, is a member of DEDDh exonuclease family. Numerous studies on various pathogens have identified essential roles ISG20 inhibiting virus replication. However, fundamental functions AEN during viral infection remain largely unknown. This study discovered that expression was significantly upregulated MARC-145 cells infected Porcine epidemic...