- Reproductive Biology and Fertility
- Acupuncture Treatment Research Studies
- Dermatology and Skin Diseases
- Ovarian function and disorders
- Immunotherapy and Immune Responses
- Complementary and Alternative Medicine Studies
- Allergic Rhinitis and Sensitization
- Radiomics and Machine Learning in Medical Imaging
- Sperm and Testicular Function
- Hepatitis B Virus Studies
- Glaucoma and retinal disorders
- Epigenetics and DNA Methylation
- Cytokine Signaling Pathways and Interactions
- Urinary and Genital Oncology Studies
- Hormonal and reproductive studies
- Bladder and Urothelial Cancer Treatments
- Corneal surgery and disorders
- Traditional Chinese Medicine Analysis
- Healthcare and Venom Research
- Adipokines, Inflammation, and Metabolic Diseases
- Neurological Disease Mechanisms and Treatments
- Advanced Synthetic Organic Chemistry
- Toxoplasma gondii Research Studies
- Biological Stains and Phytochemicals
- Urinary Bladder and Prostate Research
Hebei Medical University
2021-2025
Fourth Hospital of Hebei Medical University
2025
Institute of Group Analysis
2023-2024
Dezhou University
2024
Nanjing Medical University
2007-2022
Peking University
2022
Peking University Third Hospital
2022
Zhujiang Hospital
2021
Southern Medical University
2021
Hebei General Hospital
2021
The objective of this study was to investigate the impact cervical microflora on function and efficacy cerclage in restoring normal microecology reproductive tract, thereby improving pregnancy outcomes. Based defined inclusion exclusion criteria, six pregnant women who underwent for incompetence at Shijiazhuang No. 4 hospital between January May 2024 were enrolled. Cervical secretions collected from each participant both prior procedure one month afterward. High-throughput sequencing...
"HSR25-182: Patient-Physician Communication About Adverse Events and Impact on Quality of Life to Foster Shared Decision-Making in Chronic Myeloid Leukemia" published 28 Mar 2025 by National Comprehensive Cancer Network.
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility, affecting 5-10% females reproductive age. Currently, little known about changes in whole proteins between PCOS and normal ovaries. In present study, a proteomic approach comprised two-dimensional gel electrophoresis (2DE) analysis mass spectroscopy was used to identify examine expression patterns three One hundred ten protein spots were separated showed different intensities Sixty-nine associated with...
Abstract The TERT promoter and FGFR3 gene mutations are two of the most common genetic events in urothelial bladder cancer (UBC), these mutation assays patient urine have been shown to be promising biomarkers for UBC diagnosis surveillance. These results were obtained mainly from studies patients with Western countries, little is known about such information Han Chinese UBC. In present study, we addressed this issue by analyzing tumors 182 samples 102 mRNA expression and/or urine. identified...
Purpose: Evidence on treatment preferences of patients with moderate-to-severe atopic dermatitis (AD) in the United States (US) is limited and an assessment this group warranted.Materials methods: An online discrete choice experiment survey was conducted (June 2023) among US adults self-reported AD or experience systemic therapy who had inadequate response to topical treatments. Preference weights estimated from conditional logistic regression models were used calculate willingness trade off...
A urea-selective urine-concentrating defect was found in transgenic mice deficient urea transporter (UT)-B. To determine the role of facilitated transport extrarenal organs expressing UT-B, we studied kinetics [ 14 C]urea distribution UT-B-null versus wild-type mice. After renal blood flow disrupted, selectively reduced testis Under basal conditions, total content 335.4 ± 43.8 μg 196.3 18.2 ( P < 0.01). Testis weight (6.6 0.8 mg/g body wt) significantly greater than (4.2 wt). Elongated...
Aim:The purpose of this study was to evaluate the relationship between monocyte high-density lipoprotein cholesterol ratio (MHR) and carotid atherosclerostic plaque in patients with systemic lupus erythematosus (SLE).Methods: A total 214 SLE were divided into two groups according results ultrasonic examination: arterial atherosclerotic noncarotid atherosclerosis groups.Results: The values lipoprotein-cholesterol increase compared (0.32 ± 0.18 vs 0.26 0.15; p = 0.015).There a significant...
To investigate the expression levels of T follicular helper (Tfh) with different subsets in patients rheumatoid arthritis (RA) and their serum interleukin-6 (IL-6), interleukin-17 (IL-17), transforming growth factor-β (TGF-β) matrix metalloproteinase 3 (MMP-3) contents.The medical records 45 RA Department Rheumatology Immunology First Affiliated Hospital Chengdu Medical College from January 2016 to April 2018 were retrospectively analyzed. They divided into high activity group (24 cases, A)...
The aims of the present study were to investigate expression minichromosome maintenance complex component 7 (MCM7) and determine its association with tumor proliferation invasion in pathological (pT)a pT1 papillary urothelial neoplasia. MCM7, MCM3 Ki67 proteins detected 154 cases neoplasia using immunohistochemical analysis. MCM7 significantly increased (P<0.001) as stage grade progressed between inverted papilloma, neoplasm low malignant potential (PUNLMP), pTa tumor. However, no...
This study aimed to examine the expression and clinical significance of chemokine-like factor-like MARVEL transmembrane domain-containing family member 8 (CMTM8) in gastric cancer (GC). The mRNA protein CMTM8 were detected by bioinformatics analysis immunohistochemistry (IHC), respectively. Bioinformatics found that there was a high GC tissues, but failed identify significant relationship with clinicopathological features or prognosis patients. However, IHC results showed positive tissues...
Purpose: To develop and further validate a deep learning signature-based nomogram from computed tomography (CT) images for prediction of the overall survival (OS) in resected non-small cell lung cancer (NSCLC) patients. Patients Methods: A total 1792 features were extracted non-enhanced venous-phase CT each NSCLC patient training cohort (n=231). Then, signature was built with least absolute shrinkage selection operator (LASSO) Cox regression model OS estimation. At last, constructed other...
The sympathetic nervous system and hypothalamic-pituitary-adrenal axis have been known to be reactive psychological factors such as stress in which several humoral are released. Growing data suggest that conditions could associated with the development or aggravation of prostatic disease. present study aims investigate influence chronic blockade nerve on rat prostate.We used 2 weeks restraint water-immersion induce a model Wistar rats. Denervation peripheral was done by 6-hydroxydopamine...
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The aim of this study was to investigate whether clinical and blood parameters can be used for predicting pathological complete response (pCR) neoadjuvant chemoradiotherapy (nCRT) in patients with locally advanced rectal cancer (LARC). We retrospectively enrolled 226 LARC [allocated a 7:3 ratio training (n = 158) or validation 68) cohort] who received nCRT before radical surgery. Backward stepwise logistic regression performed identify associated achieving pCR. Models based on (CP), (BP),...
Abstract The aim of this study is to investigate changes in regulatory B cells (Bregs) and the expression related cytokines such as interleukin-10 (IL-10) transforming growth factor (TGF)-β a mouse model collagen-induced arthritis (CIA). A total 20 DBA/1 mice (6-8 weeks old) were randomly divided into control CIA disease groups. For group, animals injected intradermally with chicken collagen type II complete Freund's adjuvant. calculated index score group was significantly higher than that...
Abstract Background: Optic atrophy (OPA) is a very tricky disorder. Presently, no effective management available for this condition. Previous studies have reported that acupuncture may be the treatment of OPA. However, its effectiveness still inconclusive. Thus, study will aim to assess and safety Methods: A comprehensive literature search relevant performed from databases PUMBED, EMBASE, CINAHI, Cumulative Index Nursing Allied Health Literature, Complementary Medicine Database, Cochrane...
Bimatoprost has been reported to treat primary open-angle glaucoma (POAG) effectively. However, up-to-date, no systematic review specifically addressed the efficacy and safety of bimatoprost for treatment POAG. Therefore, this study will propose appraise POAG.We perform a search in MEDLINE, EMBASE, CINAHI, Cumulative Index Nursing Allied Health Literature, Complementary Medicine Database, Web Science, Cochrane Library, Chinese Biomedical Literature China National Knowledge Infrastructure...
Abstract Atopic dermatitis (AD) can enormously affect the lives of patients and their caregivers. Treatments for moderate-to-severe AD include phototherapy, topical systemic corticosteroids, other immunosuppressive agents biologic therapies. These treatments offer varied levels efficacy, safety, response times modes administration. Patient preferences these treatment options attributes influencing choice are not well characterized. This qualitative interview-based study evaluated important...