Yi Yan

ORCID: 0000-0002-4993-7764
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Research Areas
  • Congenital Anomalies and Fetal Surgery
  • Parasitic infections in humans and animals
  • Amoebic Infections and Treatments
  • vaccines and immunoinformatics approaches
  • Reproductive tract infections research
  • Educational Technology and Assessment
  • Cardiovascular Health and Risk Factors
  • Liver physiology and pathology
  • Systemic Lupus Erythematosus Research
  • Brucella: diagnosis, epidemiology, treatment
  • Atherosclerosis and Cardiovascular Diseases
  • Monoclonal and Polyclonal Antibodies Research
  • Physical Activity and Health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Immune Response and Inflammation
  • Parasitic Infections and Diagnostics

Jimei University
2018-2022

Xinjiang Medical University
2016-2022

First Affiliated Hospital of Xinjiang Medical University
2019-2022

To investigate the potential role of transforming growth factor (TGF)-β1 in liver fibrosis during Echinococcus granulosus infection, 96 BALB/c mice were randomly divided into 2 groups, experimental group infected by intraperitoneal injection with a metacestode suspension and control given sterile physiological saline. The blood samples collected at days 2, 8, 30, 90, 180, 270 post infection (PI), expression TGF-β1 mRNA protein was determined real-time quantitative RT-PCR ELISA, respectively....

10.3347/kjp.2016.54.4.519 article EN Korean Journal of Parasitology 2016-08-31

Aim:The purpose of this study was to evaluate the relationship between monocyte high-density lipoprotein cholesterol ratio (MHR) and carotid atherosclerostic plaque in patients with systemic lupus erythematosus (SLE).Methods: A total 214 SLE were divided into two groups according results ultrasonic examination: arterial atherosclerotic noncarotid atherosclerosis groups.Results: The values lipoprotein-cholesterol increase compared (0.32 ± 0.18 vs 0.26 0.15; p = 0.015).There a significant...

10.2217/bmm-2016-0362 article EN cc-by-nc-nd Biomarkers in Medicine 2018-03-23

The purpose of this study is to illustrate the therapeutic effect which kind polarized macrophages-based cell therapy in hepatic fibrosis caused by cystic echinococcosis.The isolation culture and polarization induction mouse bone marrow-derived macrophages (BMDM) are established an vitro environment. A model Echinococcus granulosus infection direct injection suspension into left lobe. labeled localization returned liver mice determined vivo tracing. Macrophages different types injected...

10.1016/j.biopha.2019.109178 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2019-07-01

Alveolar echinococcosis is a potentially lethal zoonosis caused by the cestode Echinococcus multilocularis. This study to investigate dynamic changes of monocytes, macrophages, and related cytokines in animal models persistent infection E. An model was established intraperitoneal injection protoscolex suspension. The pathological liver were observed HE staining. percentage Ly6Chi Ly6Clo Monocytes peripheral blood detected flow cytometry. distribution expression CX3CL1, CX3CR1, iNOS, CD163,...

10.1002/iid3.699 article EN Immunity Inflammation and Disease 2022-09-26

The aim of this study was to predict the T-cell and B-cell epitopes in major outer membrane protein (MOMP) Chlamydia trachomatis (CT) by using online software also analyse secondary structure MOMP through bioinformatics tools.The predictions were carried out SOPMA software, prediction IEDB LEPS while predicted IEBD SYFPEITHI. from combined with characteristics, including surface features, hydrophilicity, flexibility, accessibility plasticity, common epitope areas' response T-cells B-cells.In...

10.4103/ijmm.ijmm_17_251 article EN Indian Journal of Medical Microbiology 2017-10-01

Objective Large amounts of pieces evidence suggest sedentary behavior(SB) might have a negative impact on all-cause mortality, cardiovascular disease, and metabolic system. Our aim is to explore the associations between behavior risk factors in adults 40-49year.
 Methods Participants(N=372) were 40-49 years old who had survey by using adult sit-Q-7d. The indexes body mass index(BMI) Waist circumference(WC) measured as per standard protocols blood pressure an automated sphygmomanometer...

10.14428/ebr.v1i3.9373 article EN cc-by Exercise Biochemistry Review 2018-10-03

Abstract Background Alveolar echinococcosis (AE) is a potentially lethal zoonosis caused by the cestode Echinococcus multilocularis . The aim of this research to investigate dynamic changes monocytes, macrophages and related cytokines in animal models persistent infection , specifically exploring possible immune Methods An model was established intraperitoneal injection protoscolex suspension. pathological mice liver were observed HE staining score scale established. ratio Ly6C hi lo...

10.21203/rs.3.rs-20558/v2 preprint EN cc-by Research Square (Research Square) 2020-05-12

Background: Brucella is the pathogen of brucellosis, a prevalent zoonotic infectious disease in world, it mainly resides macrophages after invading body.Methods: In order to determine relationship between brucella and two types lesion sites spondylitis, distribution brucella, expression levels iNOS, Arg1 Cx3cr1 paravertebral cartilage connective tissue 40 spondylitis patients were detected by immunohistochemistry. addition clear cytokines peripheral blood macrophage polarization, level...

10.2139/ssrn.4237149 article EN SSRN Electronic Journal 2022-01-01

Based on the guiding of "Internet Plus Education", this paper researches main stream technical framework website development, designs and implements a course review system. Its implementation is divided into two parts: admin management. The includes searching information, registering, reviewing courses, modifying user viewing personal favorites, comments notices; management comment collection notice information system adopts four-layer (View- Controller-Service-Infrastructure) architecture,...

10.1145/3573428.3573453 article EN Proceedings of the 2021 5th International Conference on Electronic Information Technology and Computer Engineering 2022-10-21
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