- Microbial Metabolic Engineering and Bioproduction
- Enzyme Catalysis and Immobilization
- Plant biochemistry and biosynthesis
- Catalysis for Biomass Conversion
- Electrochemical sensors and biosensors
- Pharmacological Effects of Natural Compounds
- Lignin and Wood Chemistry
- Chemistry and Chemical Engineering
- Biochemical and biochemical processes
- Biofuel production and bioconversion
- Process Optimization and Integration
- Algal biology and biofuel production
Technical University of Munich
2016-2020
Abstract BACKGROUND Flavor and fragrance (F&F) compounds are increasingly produced by biotechnological instead of chemical means, as this allows them to be labeled natural additives. However, since most F&F exhibit cytotoxicity towards common microbiological production hosts, in situ product removal strategies using two‐phase partitioning bioreactors desirable, making the rational selection effective non‐aqueous phases a crucial step. Here, thermodynamic first‐principles methods...
Abstract Objective Geraniol, a fragrance of great importance in the consumer goods industry, can be glucosylated by UDP-glucose-dependent glucosyltransferase VvGT14a from Vitis vinifera , yielding more stable geranyl glucoside. Escherichia coli expressing is convenient whole-cell biocatalyst for this biotransformation due to its intrinsic capability UDP-glucose regeneration. The low water solubility and high cytotoxicity geraniol overcome biphasic system where non-aqueous phase functions as...