A5017087561- PARP inhibition in cancer therapy
- Cell death mechanisms and regulation
- Cancer Immunotherapy and Biomarkers
- Advanced Image and Video Retrieval Techniques
- Multimodal Machine Learning Applications
- Zebrafish Biomedical Research Applications
- Electronic Packaging and Soldering Technologies
- Vascular Malformations and Hemangiomas
- Image Retrieval and Classification Techniques
- Vascular Anomalies and Treatments
- Domain Adaptation and Few-Shot Learning
- Advanced Graph Neural Networks
- Renal and related cancers
- Aluminum Alloys Composites Properties
- 3D IC and TSV technologies
- Tissue Engineering and Regenerative Medicine
- Recommender Systems and Techniques
- MicroRNA in disease regulation
- Mesenchymal stem cell research
- Research in Cotton Cultivation
- Geophysical Methods and Applications
- Cancer-related molecular mechanisms research
- Plant and Fungal Interactions Research
- Phagocytosis and Immune Regulation
- Birth, Development, and Health
Tianjin Polytechnic University
2023-2024
University of Pittsburgh
2023-2024
Nanjing University
2021-2024
UPMC Hillman Cancer Center
2023
University of Southern California
2023
State Key Laboratory of Pollution Control and Resource Reuse
2021
North China University of Water Resources and Electric Power
2020-2021
Institute of Zoology
2013-2020
Chinese Academy of Sciences
2013-2020
University of Chinese Academy of Sciences
2017-2020
We sought to biologically characterize and identify a subpopulation of urine-derived stem cells (USCs) with the capacity for multipotent differentiation. demonstrated that single USCs can expand large population 60-70 doublings. Nine 15 individual USC clones expressed detectable levels telomerase have long telomeres. These pericyte mesenchymal cell markers. Upon induction appropriate media in vitro, differentiated into bladder-associated types, including functional urothelial smooth muscle...
Abstract Of the two cultivated species of allopolyploid cotton, Gossypium barbadense produces extra-long fibers for production superior textiles. We sequenced its genome (AD) 2 and performed a comparative analysis. identified three bursts retrotransposons from 20 million years ago (Mya) genome-wide uneven pseudogenization peak at 11–20 Mya, which likely contributed to genomic divergences. Among 2,483 genes preferentially expressed in fiber, cell elongation regulator, PRE1 , is strikingly A t...
In multimedia information retrieval, most classic approaches tend to represent different modalities of media in the same feature space. Existing take either one-to-one paired data or uni-directional ranking examples (i.e., utilizing only text-query-image image-query-text examples) as training examples, which do not make full use bi-directional (bi-directional means that both and are utilized period) achieve a better performance. this paper, we consider learning cross-media representation...
Perfluoroalkyl substances (PFASs) exist extensively and several of these have been verified to be toxic. Prenatal exposure PFASs has attracted much attention. Metabolome-wide association analyses can used explore the toxicity mechanisms by identifying associated biomarkers.To evaluate associations between metabolites in maternal cord serum internal common PFASs.Paired samples were collected from 84 pregnant women who gave birth 2015 2016. Seven legacy two novel measured. A nontarget...
Cross-modal retrieval is a classic research topic in multimedia information retrieval. The traditional approaches study the problem as pairwise similarity function problem. In this paper, we consider from new perspective listwise ranking and propose general cross-modal algorithm to optimize loss with low rank embedding, which call Latent Semantic Cross-Modal Ranking (LSCMR). latent low-rank embedding space discriminatively learned by structural large margin learning for certain criteria...
In multimedia information retrieval, most classic approaches tend to represent different modalities of media in the same feature space. With click data collected from users' searching behavior, existing take either one-to-one paired (text-image pairs) or ranking examples (text-query-image and/or image-query-text lists) as training examples, which do not make full use data, particularly implicit connections among objects. this paper, we treat a large graph, vertices are images/text queries...
Matrix factorization has been widely adopted for recommendation by learning latent embeddings of users and items from observed user-item interaction data. However, previous methods usually assume the learned are static or homogeneously evolving with same diffusion rate. This is not valid in most scenarios, where users’ preferences item attributes heterogeneously drift over time. To remedy this issue, we have proposed a novel dynamic matrix model, named Dynamic Bayesian Logistic Factorization...
The spontaneous aggregation and weak stability of nanosilver particles largely overshadowed the application paste as die-attach materials in wide bandgap (WBG) devices. Taking advantage self-decomposition silver-ammonia complexes to form silver particles, a novel particle-free was successfully developed achieve higher sintering driving force well bonding quality. proposed not only promotes decomposition complex but also reduces oxygen requirement during process, which significantly increases...
Hispidulin is a medicinal natural compound isolated from S. involucrata, which exhibits potent anticancer properties. However, there are few reports on its effects lung cancer cells. Therefore, the current study investigated of hispidulin cell viability and apoptosis in human non‑small‑cell (NSCLC) lines NCI‑H460 A549 vitro vivo. Methyl thiazolyl tetrazolium, colony formation assay, Hoechst 33342 staining, flow cytometry western blotting were performed Human A mouse xenograft model was also...
Thermomechanical stress caused by the coefficient of thermal expansion (CTE) mismatch leads to formation cracks, delamination, and warpage in sintered nano-silver (S-Ag) layer, which eventually results fatigue failure silicon carbide (SiC) semiconductor devices. Herein, gradient porosity distribution method was proposed simultaneously reduce maximum thermomechanical homogenize distribution. The influence different distributions on strain S-Ag layer investigated finite element simulation....
Due to the describable or human-nameable nature of visual attributes, attribute-based methods have been receiving much attentions in recent years many applications. The advantages utilization attributes are that they can be composed create descriptions at various levels specificity learned once and then applied recognize new objects categories. Therefore, attribute prediction becomes an essential problem boost image understanding. This paper proposes approach for correlated transfer from a...
Hematopoietic stem and progenitor cells have the capacity to self-renew differentiate into all blood cell lineages, thus sustain life-long homeostasis of hematopoietic system. Although intensive studies focused on orchestrated genetic network specification expansion, relatively little is known regulation survival during embryogenesis. Here, we generated two types miR-142a-3p mutants in zebrafish showed that loss-of-function displayed severe reduction cells. Further analysis diminished...
The caudal hematopoietic tissue in zebrafish, the equivalent to fetal liver mammals, is an intermediate niche for maintenance and differentiation of stem progenitor cells before homing thymus kidney marrow. As one ultimate organs, sustains T lymphopoiesis, which essential adaptive immune system. However, mechanism prethymic lymphoid progenitors migrating remains elusive. In this study, we identify Rho GTPase Rac2 as a modulator zebrafish. rac2-Deficient embryos show inability because...
In this paper, a method that uses ground-penetrating radar (GPR) and the adaptive particle swarm support vector machine (SVM) is proposed for detecting recognizing hidden layer defects in highways. Three common road features, namely cracks, voids, subsidence, were collected using imaging. Image segmentation was performed on acquired images. Original features extracted from thresholded binary images compressed kl algorithm. The SVM classification algorithm used condition classification. For...
To support cross-modal information retrieval, learning to rank approaches utilize ranking examples (e.g., an example may be a text query and its corresponding ranked images) learn appropriate (similarity) function. However, the fact that each modality is represented with intrinsically different low-level features hinders these from better reducing heterogeneity-gap between modalities thus giving satisfactory retrieval results. In this paper, we consider neural networks, perspective of...
A simple HPLC method for the simultaneous determination of phenylglyoxylic acid (PGA), mandelic (MA), styrene glycol (SG) and hippuric (HA) in cell culture medium was developed. Analysis performed on a C(18) column with mobile phase composed methanol-potassium dihydrogen phosphate (pH 2.5; 10 mM; 10:90, v/v) at 220 nm. The flow-rate set 0.5 mL/min. mean absolute recoveries PGA, MA, SG HA were 95.9, 98.4, 98.0 97.1%, respectively. inter-day intra-day precisions, determined three concentration...
Induction of programmed cell death (PCD) is a key cytotoxic effect anticancer therapies. PCD not confined to caspase-dependent apoptosis, but includes necroptosis, regulated form necrotic controlled by receptor-interacting protein (RIP) kinases 1 and 3, mixed lineage kinase domain-like (MLKL) pseudokinase. Necroptosis functions as defense mechanism against oncogenic mutations pathogens can be induced variety agents. However, the functional role regulatory mechanisms necroptosis in therapy...
You have accessJournal of UrologyStem Cell Research1 Apr 2013249 HUMAN URINE-DERIVED STEM CELLS ORIGINATE FROM PARIETAL Rongpei Wu, Guihua Liu, Yuxin Fan, Jan Rohozinski, Xinyan Lu, Gilma Rodriguez, Alan Farney, Anthony Atala, and Yuanyuan Zhang WuRongpei Wu Winston Salem, NC , LiuGuihua Liu FanYuxin Fan Houston, TX RohozinskiJan Rohozinski LuXinyan Lu RodriguezGilma Rodriguez FarneyAlan Farney AtalaAnthony Atala ZhangYuanyuan View All Author...
Geometric matrix completion (GMC) has been proposed for recommendation by integrating the relationship (link) graphs among users/items into (MC). Traditional GMC methods typically adopt graph regularization to impose smoothness priors MC. Recently, geometric deep learning on (GDLG) is solve problem, showing better performance than existing including traditional based methods. To best of our knowledge, there exists only one GDLG method GMC, which called RMGCNN. RMGCNN combines convolutional...
Aiming at the low frequency oscillation and voltage drop caused by wind-thermal bundled system transmitted to load center across AC DC lines, an adaptive sliding mode gain control method based on structure decentralized theory is proposed. On basis of this method, a rotor-side terminal controller for doubly-fed induction generator synchronous rotating coordinate designed. Based RTDS, real-time simulation platform transient stability "wind-thermal bundled" transmission was developed,...
We present UniPLV, a powerful framework that unifies point clouds, images and text in single learning paradigm for open-world 3D scene understanding. UniPLV employs the image modal as bridge to co-embed points with pre-aligned shared feature space without requiring carefully crafted cloud pairs. To accomplish multi-modal alignment, we propose two key strategies:(i) logit distillation modules between (ii) vison-point matching module is given explicitly correct misalignment caused by pixels...