1. The deposition of fat during pregnancy and its subsequent mobilization lactation was studied in the rat. utilization protein also investigated. 2. Fat accumulation rapid continuous from early pregnancy. Approximately one-third deposited subcutaneously, remainder being stored central depots. 3. volume milk produced varied by offering at two concentrations day 2 post partum. Optimum achieved with a high-protein diet. dams lost no body protein, but 60% total mobilized, despite marked...

Abstract In the hippocampus, CA1 region is selectively vulnerable to effects of chronic prenatal ethanol exposure. guinea‐pig, number pyramidal cells decreased after We tested hypotheses that exposure (through maternal ingestion) results in impairments spatial learning and short‐ long‐term plasticity postnatal guinea‐pig hippocampus. Timed, pregnant guinea‐pigs were treated with (4 g/kg body weight/day), isocaloric sucrose/pair‐feeding, or water throughout gestation. Offspring studied...

Malignant spinal cord compression (mSCC) is one of the most serious complications cancer. Recent NICE guidance has aimed to improve patient pathways and outcomes for patients with mSCC. We have examined current presentations, management mSCC in West London following implementation guidance.The electronic records clinical notes were reviewed all assessed confirmed or potential at Charing Cross Hospital 2012. Details on number referrals, proportion mSCC, cancer diagnosis, treatment outcome...

BACKGROUND: Treatment of rectal cancer in North America has been associated with lower rates sphincter-preserving surgery comparison other regions. It is unclear if these are due to patient, tumor, or treatment factors; thus, the potential increase use unknown. OBJECTIVE: The aim this study identify factors and quantify for an sphincter preservation. DESIGN: This population-based retrospective cohort used patient-level data collected through a comprehensive, standardized review hospital...

In Brief Objective: To determine whether surgeon knowledge contributes to the relationship between procedure volume and patient outcomes in rectal cancer. Background: Although previous research has shown that treatment by high-volume surgeons is associated with improved among patients cancer, mechanisms for such an association are not well understood. Methods: 2009, a mail survey 8 questions pertaining cancer care was created, modified content validity, sent all general Nova Scotia, Canada....

There are limited data on health care use among survivors of young adult cancers. We aimed to describe patterns hospitalization a cohort long-term compared with noncancer controls.Persons diagnosed between the ages 20 and 44 years malignancies in Ontario, Canada, from 1992 1999, who lived at least 5 recurrence free, were identified using Ontario Cancer Registry matched controls. Hospitalizations determined hospital discharges, rates The absolute excess rate hospitalizations was for each type...

Objectives: Screening rates for colorectal cancer (CRC) remain suboptimal. The impact of provider strategies to enhance screening participation in the population is uncertain. objective this study was determine effect increase a single-payer system. Methods: A population-based survey conducted primary care providers (PCPs) linked patients using administrative data Ontario, Canada. Patients were due CRC from April 2012 March 2013. followed up until 31 2014. We determined time become...

Abstract Aim Factors associated with verified post‐colonoscopy colorectal cancers (PCCRC) have not been well defined and survival for these patients is described. We aimed to assess the association of patient, tumour endoscopist characteristics PCCRC. Methods Using population‐based data, we identified individuals diagnosed CRC from 1 January 2000 31 December 2005 who underwent a colonoscopy within 3 years prior diagnosis. Detected were those ≤6 months following colonoscopy; PCCRC >6 ≤3...

ABSTRACT The hypothesis that feline urine pH can be manipulated by use of varying amounts natural food components was tested. A relatively simple experimental model constructed whereby soybean meal in a basal calculogenic diet substituted other at levels and the changes measured. In different phase experiment result rapid change used to show speed response pH. effect acidifying compounds also demonstrated model. prophylactic three on compared, with corn gluten most potent. urological...

Ileal pouch anal anastomosis (IPAA) to surgically manage ulcerative colitis may involve multiple separate surgical procedures, impacting treatment costs, length of stay in hospital, complication rates and patient outcomes, there is currently no accepted standard care regarding the number stages that should be performed. The purpose this study was compare practice patterns Canadian American colorectal surgeons management colitis.A questionnaire mailed all practisng fellows Society Colon...

Patients receiving Bevacizumab, a vascular endothelial growth factor inhibitor used to treat metastatic colorectal cancer, may be at greater risk of complications after surgery because impaired healing.The purpose this study was describe population-based rates Bevacizumab treatment and evaluate the relationship between time since last complications.This retrospective cohort using administrative cancer registry data.The conducted in Ontario, Canada.Patients with January 2008 December 2011...

<h3>Background:</h3> Our objective was to examine the knowledge and treatment decision practice patterns of Canadian surgeons who treat patients with rectal cancer. <h3>Methods:</h3> A mail survey 6 questions on staging investigations, management low cancer, lymph node harvest, surgical margins use adjuvant therapies sent all general in Canada. Appropriate responses were defined a priori. We compared according surgeon training (colorectal/surgical oncology v. others) geographic region...

There is growing awareness of the significant mental health impacts COVID-19 pandemic on many Americans. Less known about effects individuals who were living with conditions prior to pandemic's onset. In addition, little research has explored how this group coping positively challenges COVID-19. Understanding strengths these bring demands and disruptions can inform recovery for in aftermath public emergency. Using results from a cross-sectional, online survey administered during April May...

ABSTRACT Background Coal mining involves heavy physical demand, which is associated with increased risk of injury and long‐term musculoskeletal health disorders chronic pain. Management or recurrent pain in turn prescription opioid use disorder (OUD). Methods We analyzed clinical data from 5463 coal miners evaluated between 2004 2015. Using an iterative text procedure, we structured notes to extract information on occupational histories data. associations along the causal chain using a...

288 Background: The use of electronic medical records (EMR) by primary care physicians (PCP) is promoted as a method to enhance screening rates, however the impact these systems on participation uncertain. purpose this study was determine if EMR among population-based sample Ontario PCPs affects colorectal cancer (CRC) their patients. Methods: A survey sent 1,463 randomly selected in regarding adoption and management enabled EMR. Patients who were treated PCP respondents identified from...

<h3></h3> There has been a significant increase in infectious syphilis men who have sex with men(MSM) Recent data also suggests corresponding ano-rectal syphilis. Despite this, there is lack of testing MSM symptoms. The aim this study to describe the presentation and management sexual health clinic Brighton sees 6500 per year for sexually transmitted infection treatment. We reviewed electronic notes from January 2017 August 2020 collected on patient demographics, HIV status, previous...

Abstract Aim Disruption to undergraduate clinical training during the COVID-19 pandemic caused a perceived lack of preparedness amongst newly qualified junior doctors. We aimed improve doctor in surgery, through development and implementation an induction booklet. Method An electronic survey distributed December 2021 assessed doctors’ for their surgical job identified inadequacies existing programme. Through feedback suggestions, we designed 30-page booklet containing information each...