A5053322693- 3D Printing in Biomedical Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Additive Manufacturing and 3D Printing Technologies
- Photopolymerization techniques and applications
- Robotic Path Planning Algorithms
- Biosensors and Analytical Detection
- Robotics and Sensor-Based Localization
- Neuroscience and Neural Engineering
- Advanced Drug Delivery Systems
- Advanced biosensing and bioanalysis techniques
- Advanced Vision and Imaging
- Injection Molding Process and Properties
- Drug Solubulity and Delivery Systems
- Cell Image Analysis Techniques
- Advanced Sensor and Energy Harvesting Materials
- Advancements in Transdermal Drug Delivery
- Biomedical and Engineering Education
- Opioid Use Disorder Treatment
- Ocular Surface and Contact Lens
- Wireless Body Area Networks
- Advanced Image and Video Retrieval Techniques
- Pain Mechanisms and Treatments
- Neuroethics, Human Enhancement, Biomedical Innovations
- Spaceflight effects on biology
- IoT and Edge/Fog Computing
University College London
2020-2024
National University of Singapore
2010
Ulcerative colitis is a global health problem, affecting millions of individuals worldwide. As an inflammatory condition localised in the large intestine, rectal delivery immunosuppressive therapies such as tacrolimus promising strategy to maximise drug concentration at site action whilst minimising systemic side effects. Here, for first time, self-supporting 3D-printed suppositories were prepared without aid moulds using pharmaceutical semi-solid extrusion (SSE) 3D printer. The printed...
Abstract With the impending Industrial Revolution 4.0, information produced by sensors will be central in many applications. This includes healthcare sector, where affordable and precision medicine are highly sought after. Electrochemical have potential to produce affordable, high sensitivity specificity, intuitive, rapid point‐of‐care diagnostics. Underpinning these achievements is choice of material fabrication thereof. In this review, different types materials used electrochemical...
3D printing (3DP), or additive manufacturing, has been actively investigated as one of the enabling technologies for impending era personalized medicines. However, existing 3DP do not afford speeds required on-demand production medicines in fast-paced clinical settings. Volumetric is a novel technology that offers rapid speed and overcomes geometric surface quality limitations layer-based vat photopolymerization techniques. Unlike previous technologies, volumetric cures entire desired...
Inkjet printing has been extensively explored in recent years to produce personalised medicines due its low cost and versatility. Pharmaceutical applications have ranged from orodispersible films complex polydrug implants. However, the multi-factorial nature of inkjet process makes formulation (e.g., composition, surface tension, viscosity) parameter optimization nozzle diameter, peak voltage, drop spacing) an empirical time-consuming endeavour. Instead, given wealth publicly available data...
Pharmaceutical 3D printing (3DP) is one of the emerging enabling technologies personalised medicines as it affords ability to fabricate highly versatile dosage forms. In past 2 years, national regulatory authorities have held consultations with external stakeholders adapt frameworks embrace point-of-care manufacturing. The proposed concept decentralized manufacturing (DM) involves provision feedstock intermediates (pharma-inks) prepared by pharmaceutical companies DM sites for into final...
3D printing is driving a shift in patient care away from generalised model and towards personalised treatments. To complement fast-paced clinical environments, technologies must provide sufficiently high throughputs for them to be feasibly implemented. Volumetric an emerging technology that affords such speeds, being capable of producing entire objects within seconds. In this study, the first time, rotatory volumetric was used simultaneously produce two torus- or cylinder-shaped...
Semi-solid extrusion (SSE) is a three-dimensional printing (3DP) process that involves the of gel or paste-like material via syringe-based printhead to create desired object. In pharmaceuticals, SSE 3DP has already been used manufacture formulations for human clinical studies. To further support its adoption, use pressure sensor may provide information on printability feedstock in situ and under exact conditions quality control purposes. This study aimed integrate an pharmaceutical 3D...
Abstract Mutable devices and dosage forms have the capacity to dynamically transform dimensionally, morphologically mechanically upon exposure non-mechanical external triggers. By leveraging these controllable transformations, systems can be used as minimally invasive alternatives implants residence devices, foregoing need for complex surgeries or endoscopies. 4D printing, fabrication of 3D-printed structures that evolve their shape, properties, functionality in response stimuli over time,...
Recent advancements in next generation spacecrafts have reignited public excitement over life beyond Earth. However, to safeguard the health and safety of humans hostile environment space, innovation pharmaceutical manufacturing drug delivery deserves urgent attention. In this review/commentary, current state medicines provision space is explored, accompanied by a forward look on future outer space. The hazards associated with spaceflight, their corresponding medical problems, are first...
Vat photopolymerization has garnered interest from pharmaceutical researchers for the fabrication of personalised medicines, especially drugs that require high precision dosing or are heat labile. However, 3D printed structures created thus far have been insoluble, limiting printable dosage forms to sustained-release systems drug-eluting medical devices which do not dissolution matrix. Resins produce water-soluble will enable more versatile drug release profiles and expand potential...
Inkjet printing has the potential to advance treatment of eye diseases by drugs on demand onto contact lenses for localised delivery and personalised dosing, while near-infrared (NIR) spectroscopy can further be used as a quality control method quantifying drug but yet demonstrated with lenses. In this study, glaucoma therapy drug, timolol maleate, was successfully printed using modified commercial inkjet printer. The drug-loaded ink prepared printer designed match properties ink, whilst...
This paper describes the development of an Unmanned Aerial Vehicle (UAV) with aid a vision processing system for indoor navigation. A co-axial radio-controlled (RC) helicopter is upgraded customized on-board avionics which include two Gumstix Linux computer systems as processors. camera module used to capture real time video during flight perform image processing. High level control commands are sent such that UAV could simple navigation by tracking colored tracks on ground. Important data...
This paper describes the design and construction of an autonomous indoor coaxial rotorcraft system with onboard vision processing capability. A radio-controlled (RC) helicopter was modified upgraded essential avionics elements for flight. shows that in environment, where GPS signals are unavailable, vision-based navigation can be used as a substitution. An embedded is compact light enough to carried by UAVs integrated into control loop. The has been successfully tested UAV able follow...
<title>Abstract</title> Mutable devices and dosage forms have the capacity to dynamically transform dimensionally, morphologically mechanically upon exposure non-mechanical external triggers. By leveraging these controllable transformations, systems can be used as minimally invasive alternatives implants residence devices, foregoing need for complex surgeries or endoscopies. 4D printing, fabrication of 3D-printed structures that evolve their shape, properties, functionality in response...