A5010011782- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Synthesis and Reactions of Organic Compounds
- Acute Myocardial Infarction Research
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Enzyme Structure and Function
- Psychedelics and Drug Studies
- Sulfur-Based Synthesis Techniques
- African Botany and Ecology Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Synthesis and Characterization of Heterocyclic Compounds
- Nutritional Studies and Diet
- Organic Chemistry Cycloaddition Reactions
- Chemical Reaction Mechanisms
- Infectious Diseases and Tuberculosis
- Piperaceae Chemical and Biological Studies
- Research on Leishmaniasis Studies
- Antimicrobial Resistance in Staphylococcus
- Plant Growth Enhancement Techniques
- Intracranial Aneurysms: Treatment and Complications
- Facial Trauma and Fracture Management
- Gastroesophageal reflux and treatments
RMIT University
2023-2024
The University of Queensland
2024
ARC Centre of Excellence for Plant Success in Nature and Agriculture
2024
Agriculture and Food
2024
New Hampshire Sea Grant
2023
University of New Hampshire
2023
University of New Hampshire at Manchester
2023
Walter and Eliza Hall Institute of Medical Research
2021
St Thomas' Hospital
2019-2021
St George's Hospital
2020
Near-death experiences (NDEs) are complex subjective experiences, which have been previously associated with the psychedelic experience and more specifically induced by potent serotonergic, N,N-Dimethyltryptamine (DMT). Potential similarities between both states noted previously, including feeling of transcending one's body entering an alternative realm, perceiving communicating sentient 'entities' themes related to death dying. In this within-subjects placebo-controled study we aimed test...
Zairean medicinal plants were extracted and screened for in vitro antibacterial antifungal activities. Of nine investigated, extracts of six (Alchornea cordifolia, Bridelia ferruginea, Eucalyptus citriodora, Hymenocardia acida, Maprounea africana Sida rhombifolia) demonstrated a marked activity against the microorganisms Klebsiella pneumoniae, Staphylococcus aureus Streptococcus mutans; four (A. E. M. S. exhibited significant Aspergillus niger, Candida albicans Microsporum gypseum. Extracts...
Sulfathiazole, a compound that forms four known crystal structures, has been examined with view to understanding its polymorphism. A graph set approach was used classify the structural differences and similarities of polymorphs, results which indicated packing motifs common three structures. By combining this analysis experimental morphological data, it possible examine origins observed solvent dependence polymorph appearance in system. In particular, link between hydrogen-bond each form...
The evaluation of anticancer and anti-HIV activities extracts from nine medicinal plants collected in Zaire was carried out against the National Cancer Institute (NCI) panel human tumor cell lines provided for preliminary screening natural products. methanol root bark Hymenocardia acida, stem Mangifera indica leaves Sida rhombifolia, exhibited cytotoxic activity 60 tested. Of these, extract M. produced an interesting pattern differential cellular sensitivity MDA-MB-231, MDA-MB-435, MDA-N...
Hemp is low-tetrahydrocannabinol (THC) Cannabis sativa that cultivated globally for food and fibre. seeds seed-oil are popularly consumed individually or utilised within cooking, due to their flavour, nutrition, functional benefits. The properties of hemp seed include its beneficial fatty acid (FA) profile antioxidant activity, which associated with reduced inflammation benefits chronic conditions including cardiovascular disease cancer. Maximising these can offer extensive health...
The screening of African medicinal plants, utilized in traditional herbal remedies Ghana West Africa for their antibacterial and antifungals activities, is reported this paper. Of ten plants tested, extracts five (Phyllanthus niruri, Ageratum conyzoides, Acanthospermum hispidum, Cassia alata, Sida acuta) had activity against the Gram positive microorganism Staphylococcus aureus including methicillin-resistant (MRSA). None these have previously anti-MRSA or lack documented. Hexane from three...
Abstract The synthesis of 1‐azaphenoxathiin, the parent ring system a recently reported class novel CNS agents is described. 13 C‐nmr spectrum and its assignment are also as model for structure confirmation studies.
Background Early triage is essential to improve outcomes in patients with suspected acute myocardial infarction ( AMI ). This study investigated whether cMyC (cardiac myosin‐binding protein), a novel biomarker of necrosis, can aid early diagnosis and risk stratification. Methods Results high‐sensitivity cardiac troponin T were retrospectively quantified blood samples obtained by ambulance‐based paramedics prospective, diagnostic cohort study. Patients ongoing or prolonged periods chest...
Abstract The condensation of the disodium salt 2‐mercapto‐3‐pyridinol with various ortho ‐nitrohalo‐benzenes to yield a group previously unreported 1‐azaphenoxathiins is described. synthetic pathway and substituent location on products unequivocably demonstrated by Fourier Transform 1 3 C‐nmr. Preliminary pharmacologic evaluation title compounds as potential CNS depressant agents also reported.
Abstract Objectives Cardiac myosin-binding protein C (cMyC) is a novel biomarker of myocardial injury, with promising role in the triage and risk stratification patients presenting acute cardiac disease. In this study, we assess weekly biological variation cMyC, to examine its potential monitoring chronic suggest analytical quality specification for routine use test clinical practice. Methods Thirty healthy volunteers were included. Non-fasting samples obtained once week ten consecutive...
Redetermination of the structure DL-norleucine (2-aminohexanoic acid), C6H13NO2, has given more accurate geometrical information than early work Mathieson [Acta Cryst. (1953), 6, 399-403]. Synchrotron radiation Laue diffraction patterns recorded over a range temperatures have shown (a) presence streaks, indicating disorder in stacking layers within crystal at room temperature, (b) complete or almost disappearance these streaks when is heated to ca 373 K, annealing crystal, and (c) loss...
Abstract Climate change is increasingly impacting marine fisheries worldwide. Concurrently, scientific interest has grown to understand how these systems can cope and adapt, with research shifting from examining vulnerability assessing risks focusing on determining operationalizing resilience. As fisheries-climate-resilience researchers practitioners navigating a sea of frameworks, toolkits, strategies, policy goals, management desires, we take stock ask: what does resilience mean us?...
In a combined modeling and experimental study the twin interface in saccharin crystals has been used as basis for energetic calculations visualization of solid−solid interface. A methodology developed that wide applicability to range interfaces between crystalline materials.
Summary Climate change is threatening our current food systems and countries around the world are seeking alternative sources to safeguard against potential insecurity nutrient deficiency concerns. Various traditional foods used by Aboriginal groups of Australia have previously been shown be highly nutritious, contain beneficial functional properties can thrive in harsh climatic conditions found across Australia. As interest these grows, looking at developing a range for modern markets....
Ensuring Indigenous producers realize and capture provenance value from the native foods botanicals supply chain is a key part of achieving economic, community, ecological sustainability for communities. Utilizing blockchain technology to support validated claims throughout processes an important intervention toward this objective. This paper presents preliminary results ongoing project in which underpins “whole chain” approach addressing issues how these are within digitalized environment....