Nicholos Joseph

ORCID: 0000-0001-9365-879X
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About
Contact & Profiles
Research Areas
  • Healthcare Systems and Technology
  • CAR-T cell therapy research
  • COVID-19 and healthcare impacts
  • Radiology practices and education
  • Anesthesia and Sedative Agents
  • Disaster Response and Management
  • Viral Infectious Diseases and Gene Expression in Insects
  • Interprofessional Education and Collaboration
  • Social Media in Health Education
  • Innovations in Medical Education
  • Virus-based gene therapy research
  • Pain Management and Opioid Use
  • Patient-Provider Communication in Healthcare
  • Global Health Workforce Issues
  • COVID-19 Clinical Research Studies
  • Child and Adolescent Health
  • Anesthesia and Pain Management
  • CRISPR and Genetic Engineering
  • COVID-19 diagnosis using AI
  • Diversity and Career in Medicine
  • Telemedicine and Telehealth Implementation
  • Monoclonal and Polyclonal Antibodies Research

Harvard University
2020-2023

Massachusetts General Hospital
2020-2023

Baylor College of Medicine
2015-2016

Texas Children's Hospital
2016

Methodist Hospital
2016

Houston Methodist
2016

On March 17, 2020, the Association of American Medical Colleges recommended suspension all direct patient contact responsibilities for medical students because COVID-19 pandemic. Given this change, nationwide had to grapple with how and where they could fill evolving needs their schools' affiliated clinical sites, physicians, patients, community.At Harvard School (HMS), student leaders created a Student Response Team to: (1) develop student-led organizational structure that would optimize...

10.1097/acm.0000000000003401 article EN Academic Medicine 2020-04-09

Immunotherapy with CD123-specific T-cell engager proteins or T cells expressing chimeric antigen receptors is actively being pursued for acute myeloid leukemia. secreting bispecific molecules (ENG-T cells) may present a promising alternative to these approaches. To evaluate therapeutic potential, we generated secrete CD123/CD3-bispecific molecules. CD123-ENG recognized primary leukemia (AML) and cell lines in an antigen-dependent manner as judged by cytokine production and/or tumor killing,...

10.1038/mt.2016.116 article EN cc-by-nc-nd Molecular Therapy 2016-07-12

Background Disease severity on chest radiographs has been associated with higher risk of disease progression and adverse outcomes from coronavirus 2019 (COVID-19). Few studies have evaluated COVID-19-related racial and/or ethnic disparities in radiology. Purpose To evaluate whether non-White minority patients hospitalized confirmed COVID-19 infection presented increased admission compared White or non-Hispanic patients. Materials Methods This single-institution retrospective cohort study was...

10.1148/radiol.2020202602 article EN Radiology 2020-07-16

Abstract Although ablations are performed with conscious sedation or general anesthesia, microwave can be painful post procedure. Newer analgesic modalities, including regional blocks, have promoted the proliferation of less invasive anesthesia care for ablative procedures. This study evaluates whether bilateral paravertebral blocks reduce need additional analgesics in comparison to unilateral ablations. In this retrospective study, individuals undergoing ablation who underwent versus nerve...

10.1038/s41598-023-36607-1 article EN cc-by Scientific Reports 2023-08-24

Meeting abstracts T cell immunotherapy is one promising approach to improve outcomes for patients with AML; however, infused cells do not redirect resident tumors. To overcome this, we have genetically modified produce a secretable, bispecific engager (ENG-T cells).

10.1186/2051-1426-3-s2-p3 article EN cc-by Journal for ImmunoTherapy of Cancer 2015-11-04

As online messaging between patients and providers grows, so does the need for training on best practices surrounding electronic communication with patients. Undergraduate graduate medical education must prepare trainees this aspect of practice, but there are limited data how to engage in written Medical student participation patients, under supervision, provides a novel educational opportunity develop important patient care skills. Post-clerkship students were paired primary faculty. No was...

10.1111/medu.15040 article EN Medical Education 2023-02-23
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