A5051452109- Global Peace and Security Dynamics
- Head and Neck Surgical Oncology
- African history and culture analysis
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Radiology practices and education
- Infectious Diseases and Tuberculosis
- Orthopedic Surgery and Rehabilitation
- Spinal Fractures and Fixation Techniques
- Vascular Malformations Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Sinusitis and nasal conditions
- Intracranial Aneurysms: Treatment and Complications
- Meningioma and schwannoma management
- Historical and Contemporary Political Dynamics
- Medical Imaging and Pathology Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Sarcoma Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Soft tissue tumor case studies
- Dermatological and Skeletal Disorders
- International Law and Human Rights
- Spine and Intervertebral Disc Pathology
- Glioma Diagnosis and Treatment
Johns Hopkins University
2005-2025
Johns Hopkins Bayview Medical Center
2024-2025
Icahn School of Medicine at Mount Sinai
2024
Blanchette Rockefeller Neurosciences Institute
2024
West Virginia University
2024
Sun Yat-sen Memorial Hospital
2024
Sun Yat-sen University
2024
Johns Hopkins Medicine
2024
Shanxi University
2024
Allama Iqbal Medical College
2024
Significance Human pluripotent stem cells (hPSCs) can be produced from any person and have the potential to differentiate into cell type in body. This study focuses on generation of insulin-expressing hPSCs compares their gene expression, as assayed by transcriptional products, that β human fetal adult samples. We employ a new method isolate profile conclude several different hPSC lines generate very similar cells, whose transcripts resemble rather than cells. advances possibility directing...
Purpose To develop an automated measure of COVID-19 pulmonary disease severity on chest radiographs for longitudinal tracking and outcome prediction. Materials Methods A convolutional Siamese neural network–based algorithm was trained to output a (pulmonary x-ray [PXS] score), using weakly supervised pretraining approximately 160 000 anterior-posterior images from CheXpert transfer learning 314 frontal patients with COVID-19. The evaluated internal external test sets different hospitals (154...
Sovereignty, according to the authors, can no longer be seen as a protection against interference, but charge of responsibility where state is accountable both domestic and external constituencies. In internal conflicts in Africa, sovereign states have often failed take for their own citizens' welfare humanitarian consequences conflict, leaving victims with or assistance. This book shows how that exercised by over populations other assistance fellow sovereigns. The authors present framework...
Ce document a pour but d'enoncer les principes relatifs aux droits concernant personnes deplacees diverses raisons de menace leur securite (guerre, catastrophe, etc.). Apres avoir mentionne le principe prohibition du recours arbitraire au deplacement population et la prevention des conditions pouvant conduire deplacements massifs, texte expose selon lesquels protection, assistance respect dignite (conditions vie, non separation familles, etc.) doivent etre reconnus sans discrimination comme...
Since the end of Cold War, increasing numbers people have been forced to leave their homes as a result armed conflict, internal strife, and systematic violations human rights. Whereas refugees crossing national borders benefit from an established system international protection assistance, those who are displaced internally suffer absence legal or institutional bases for assistance community. This book analyzes causes consequences displacement, including its devastating impact both within...
Infantile spasms syndrome (ISS) is a catastrophic pediatric epilepsy with motor spasms, persistent seizures, mental retardation, and in some cases, autism. One of its monogenic causes an insertion mutation [c.304ins (GCG)(7)] on the X chromosome, expanding first polyalanine tract interneuron-specific transcription factor Aristaless-related homeobox (ARX) from 16 to 23 alanine codons. Null Arx gene impairs GABA cholinergic interneuronal migration but results neonatal lethal phenotype. We...
The civil war that has intermittently raged in the Sudan since independence 1956 is, according to Francis Deng, a conflict of contrasting and seemingly incompatible identities Northern Southern parts country. Identity is seen as function how people identify themselves are identified racial, ethnic, cultural, linguistic, religious terms. identity question related such concepts determine or influence participation distribution political, economic, social, cultural life War Visions aims at...
Transcriptional profiling is a key technique in the study of cell biology that limited by availability reagents to uniquely identify specific types and isolate high quality RNA from them. We report Method for Analyzing following Intracellular Sorting (MARIS) generates transcriptome cellular fixation, intracellular immunofluorescent staining FACS. MARIS can therefore be used many otherwise inaccessible simply based on tagging unique proteins. As proof principle, we sorted human embryonic stem...
A large body of evidence indicates that retrieval practice (test-enhanced learning) and spaced repetition increase long-term information retention. Implementation these strategies in medical curricula is unfortunately limited. However, students may choose to apply them autonomously when preparing for high-stakes, cumulative assessments, such as the United States Medical Licensing Examination Step 1. We examined prevalence specific self-directed methods testing, with or without repetition,...
Abstract Background and Purpose Distal medium vessel occlusions (DMVOs) are a significant contributor to acute ischemic stroke (AIS), with collateral status (CS) playing pivotal role in modulating damage progression. We aimed explore baseline characteristics associated CS AIS‐DMVO. Methods This retrospective analysis of prospectively collected database enrolled 130 AIS‐DMVO patients from two comprehensive centers. Baseline characteristics, including patient demographics, admission National...
Recent large core trials have highlighted the effectiveness of mechanical thrombectomy (MT) in acute ischemic stroke with vessel occlusion. Variable perfusion-imaging thresholds and poor Alberta Stroke Program Early Computed Tomography Score reliability underline need for more standardized, quantitative ischemia measures MT patient selection. We aimed to identify computed tomography perfusion parameter most strongly associated outcomes patients stroke-large occlusion significant cores.
Background Disease severity on chest radiographs has been associated with higher risk of disease progression and adverse outcomes from coronavirus 2019 (COVID-19). Few studies have evaluated COVID-19-related racial and/or ethnic disparities in radiology. Purpose To evaluate whether non-White minority patients hospitalized confirmed COVID-19 infection presented increased admission compared White or non-Hispanic patients. Materials Methods This single-institution retrospective cohort study was...
Abstract Background and Purpose Ischemic strokes due to isolated posterior cerebral artery (PCA) occlusions represent 5% of all but have significant impacts on patients’ quality life, primarily visual deficits thalamic involvement. Current guidelines for acute PCA occlusion management are sparse, the prognostic value perfusion imaging parameters remains underexplored. Methods We conducted a retrospective analysis 32 patients with treated at Johns Hopkins Medical Institutions between January...
While dramatic changes are taking place on the international scene and among major powers, Africa continues to suffer from a multitude of violent conflicts. The toll these conflicts is monumental in terms war damage productivity, scarce resources diverted armaments military organizations, resulting insecurity, displacement, destruction. At same time, Africans, response internal demands as well changes, have begun focus their attention energies problems trying innovative ways resolve...
ABSTRACT Background Gender disparities are prevalent in medicine, but their impact on surgical training is not well studied. Objective To quantify gender trainee intraoperative experiences and explore the variables associated with ratings of autonomy performance. Methods From September 2015 to May 2019, attending surgeons trainees from 71 programs assessed a 4-level Zwisch scale performance 5-level modified Dreyfus after procedures. Multivariable regression models were used examine...
Current state-of-the-art natural language processing (NLP) techniques use transformer deep-learning architectures, which depend on large training datasets. We hypothesized that traditional NLP may outperform transformers for smaller radiology report
Abstract Objective Venous outflow (VO) impairment predicts unfavorable outcomes in patients with acute ischemic stroke caused by large vessel occlusion (AIS‐LVO). Prolonged venous transit (PVT), a visual qualitative VO marker on CT perfusion (CTP) time to maximum (Tmax) maps, has been associated 90‐day functional despite successful reperfusion. This study investigates the association between PVT and percent change National Institutes of Health Stroke Scale (NIHSS) among AIS‐LVO who have...