A5074376265- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Telemedicine and Telehealth Implementation
- Dysphagia Assessment and Management
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebral Palsy and Movement Disorders
- Nursing Roles and Practices
- Neurological Disorders and Treatments
- Dementia and Cognitive Impairment Research
- COVID-19 and healthcare impacts
- Autoimmune Neurological Disorders and Treatments
- Hemodynamic Monitoring and Therapy
- Neurological Complications and Syndromes
- Health Sciences Research and Education
- Intensive Care Unit Cognitive Disorders
- Health Policy Implementation Science
- Retinal and Optic Conditions
- Interprofessional Education and Collaboration
- Blood Pressure and Hypertension Studies
- Thermoregulation and physiological responses
- Tracheal and airway disorders
- Long-Term Effects of COVID-19
- HIV Research and Treatment
Johns Hopkins University
2016-2025
Johns Hopkins Hospital
2008-2025
Johns Hopkins Bayview Medical Center
2024-2025
Johns Hopkins Medicine
2016-2024
Massachusetts General Hospital
2024
Rhode Island Hospital
2020-2024
Cooper Medical School of Rowan University
2024
Blakelands Hospital
2024
Phipps Houses
2024
Maroc Numeric Cluster
2023
Abstract Background Community engagement may make research more relevant, translatable, and sustainable, hence improving the possibility of reducing health disparities. The purpose this study was to explore strategies for community adopted by teams identify areas enhancing in future engaged research. Methods Engagement Program Johns Hopkins Institute Clinical Translational Research hosted a forum engage researchers partners group discussion reflect on their diverse past current experiences...
Background Acute ischaemic stroke (AIS) is a leading cause of mortality and disability globally, with volume contracted state (VCS), as indicated by an elevated blood urea nitrogen to creatinine (BUN/Cr) ratio, potentially influencing outcomes. This study investigates the association between VCS clinical outcomes in patients AIS due large vessel occlusion (LVO). Methods A retrospective cohort was conducted involving 298 LVO-AIS from two comprehensive centres. Patients were divided into...
Background and Purpose— Telemedicine is emerging as a potential timesaving, efficient means for evaluating patients experiencing acute stroke. In areas where local stroke care specialists are not available, telemedicine can link an emergency department physician with specialist in treatment center. This consultation provides opportunity administration of thrombolytic drugs within the short therapeutic time window associated ischemic Here, we describe our center experiences report safe...
Abstract Background and Purpose Ischemic strokes due to isolated posterior cerebral artery (PCA) occlusions represent 5% of all but have significant impacts on patients’ quality life, primarily visual deficits thalamic involvement. Current guidelines for acute PCA occlusion management are sparse, the prognostic value perfusion imaging parameters remains underexplored. Methods We conducted a retrospective analysis 32 patients with treated at Johns Hopkins Medical Institutions between January...
Background and Purpose— Central retinal artery occlusion results in acute visual loss with poor spontaneous recovery. Current standard therapies do not alter the natural history of disease. Several open-label clinical studies using continuous infusion thrombolytic agents have suggested that local intraarterial fibrinolysis (LIF) is efficacious treatment central occlusion. The aim to compare outcome patients presumed thromboembolic etiology treated LIF administered aliquots therapy. Methods—...
Therapeutic activity after stroke is a component of early recovery strategies. Interactive video games have been shown to be safe as an adjunct rehabilitation therapy in the medical intensive care setting, but patients with neurologic disease were often excluded from those protocols.
ABSTRACT Background and purpose Prolonged length of stay (LOS) following a stroke is associated with unfavorable clinical outcomes. Factors predicting LOS in medium vessel occlusion (MeVO), impacting up to 40% acute ischemic (AIS) cases, remain underexplored. This study aims investigate the predictors AIS‐MeVO. Methods We conducted retrospective analysis prospectively maintained databases, comprising AIS cases MeVO anterior circulation, assessed by adequate CT perfusion (CTP). Baseline data...
Background: The transition period after hospitalization for stroke is a vulnerable time patients as all adapt to new physical, cognitive, or emotional changes and destabilized comorbid conditions. Transitional care programs designed post-stroke carry the promise of improved outcomes reduced hospital readmission rates, however attendance rates these scheduled visits in other early supported discharge are reported low 35%. In addition patient specific consequences, missed clinic impact system...
Background and Purpose: The inflammatory response after ischemic hemorrhagic stroke is associated with worse clinical outcomes through immune mediated production of pro- cytokines. Repair proteins such as brain derived neurotrophic factor (BDNF) are expressed part the adaptive response. We assessed safety moderate intensity exercise in acute phase its association pro-inflammatory cytokines BDNF expression. Methods: This was a prospective, single center, randomized, pilot prescribed for...
Background and Purpose— Percutaneous endoscopic gastrostomy (PEG) tubes are widely used for enteral feeding of patients after intracerebral hemorrhage (ICH). We sought to determine whether PEG placement ICH differs by race socioeconomic status. Methods— Patient discharges with as the primary diagnosis from 2007 2011 were queried Nationwide Inpatient Sample. Logistic regression was evaluate association between race, insurance status, household income placement. Results— Of 49 946 included...
Abstract The optimal timing and intensity of early rehabilitation remain uncertain. literature has stated that too high-intensity mobility within 24 hours can result in poor outcomes as compared with the 24- to 48-hour poststroke ( Stroke 2012;43:2389–94. 2004;35:1005–9). However, few studies have shown mobilizing patients a times per day positive results 2004;35:1005–9. Cerebrovasc Dis 2010;29:352–60). In addition impairments, many after stroke dysphagia, aphasia, cognitive-linguistic...
The transition from student to practicing clinician is often a challenging and difficult period for many nurse practitioners. Newly graduated practitioners commonly describe feelings of inadequacy in assuming clinical responsibilities, lack support by team members, unclear expectations the orientation period, role isolation. This article describes formal practitioner program implemented at University Maryland Medical Center, large urban academic medical center, facilitate new into workforce....
Background Up to 25% of acute stroke patients first note symptoms upon awakening. We hypothesized that awaking with may be safely treated intravenous alteplase (IV tPA) using non-contrast head CT (NCHCT), if they meet all other standard criteria. Methods The SAfety Intravenous thromboLytics in ON awakening (SAIL ON) was a prospective, open-label, single treatment arm, pilot safety trial dose IV tPA who presented within 0–4.5 hours From January 30, 2013, September 1, 2015, twenty consecutive...
Background We hypothesized that stroke outcome is related to multiple baseline hydration-related factors including volume contracted state (VCS) and diuretic use. Methods Results analyzed a prospective cohort of subjects with ischemic <24 hours onset enrolled in acute treatment trials within VISTA (Virtual International Stroke Trials Archive). A VCS was defined based on blood urea nitrogen-to-creatinine ratio. The primary end point modified Rankin Scale score at 90 days. Primary analysis...
<h3>ABSTRACT</h3> <h3>BACKGROUND AND PURPOSE:</h3> Prolonged venous transit (PVT+) is a marker of outflow; it defined as the presence or absence time-to-maximum ≥10 seconds timing in either superior sagittal sinus torcula. This novel perfusion imaging-based metric has been associated with higher odds mortality and lower functional recovery. study aims to assess relationship between PVT on admission imaging length hospital stay large vessel occlusion strokes successfully reperfused mechanical...