A5008114238- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Traumatic Brain Injury Research
- Remote-Sensing Image Classification
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Healthcare Technology and Patient Monitoring
- Non-Invasive Vital Sign Monitoring
- Remote Sensing and Land Use
- Neurosurgical Procedures and Complications
- Heart Rate Variability and Autonomic Control
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Healthcare Operations and Scheduling Optimization
- Machine Learning in Healthcare
- Acute Ischemic Stroke Management
- Surgical Simulation and Training
- Trauma Management and Diagnosis
- Patient Safety and Medication Errors
- Hemodynamic Monitoring and Therapy
- Simulation-Based Education in Healthcare
- Cerebral Venous Sinus Thrombosis
- Electronic Health Records Systems
- Time Series Analysis and Forecasting
- Disaster Response and Management
University of Maryland, Baltimore
2016-2025
Johnson & Johnson (United States)
2025
University of Mary
2016-2025
UPMC Health System
2024
University of Pittsburgh
2024
University of Maryland Medical Center
2014-2023
University of Maryland, Baltimore County
2019-2023
Keck Hospital of USC
2021
International Trauma Anesthesia and Critical Care Society
2019
University of Maryland Medical System
2010-2018
OBJECTIVE To investigate the relationship between oxygenation and short-term outcomes in patients with traumatic brain injury (TBI). DESIGN Logistic regression analysis was used to determine whether average high (>200 mm Hg) or low (<100 PaO2 levels within first 24 hours of hospital admission correlated patient relative 100 200 Hg. SETTING Level 1 trauma center. PATIENTS We retrospectively reviewed 1547 consecutive severe TBI who survived past 12 after admission. MAIN OUTCOME MEASURES...
<h3>Importance</h3> Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a percutaneous transfemoral technique used in select centers for resuscitation and temporary hemostasis, often instead emergency department thoracotomy. The ability to perform aortic (AO) with an intravascular device allows focused at most distal level perfuse proximal regions while slowing hemorrhage injured areas. <h3>Objective</h3> To describe what date largest single-institution experience REBOA...
Background: Management strategies after severe traumatic brain injury (TBI) target prevention and treatment of intracranial hypertension (ICH) cerebral hypoperfusion (CH). We have previously established that continuous automated recordings vital signs (VS) are more highly correlated with outcome than manual end-hour recordings. One potential benefit sign data capture is the ability to detect brief episodes ICH CH. The purpose this study was establish whether a relationship exists between CH...
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a less invasive method proximal aortic compared with resuscitative thoracotomy cross-clamping (RTACC). This study time to REBOA and RTACC, both including excluding required for common femoral artery (CFA) cannulation.This was retrospective, single-institution review or RTACC performed between February 2013 January 2016. Time skin incision cross-clamp CFA cannulation by percutaneous open methods, from guide-wire insertion...
Background and Purpose— Telemedicine is emerging as a potential timesaving, efficient means for evaluating patients experiencing acute stroke. In areas where local stroke care specialists are not available, telemedicine can link an emergency department physician with specialist in treatment center. This consultation provides opportunity administration of thrombolytic drugs within the short therapeutic time window associated ischemic Here, we describe our center experiences report safe...
Earlier, more accurate assessment of secondary brain injury is essential in management patients with traumatic (TBI). We assessed the accuracy and utility high-resolution automated intracranial pressure (ICP) cerebral perfusion (CPP) recording their analysis severe TBI.ICP CPP data for 30 TBI were collected automatically at 6-second intervals. The degree duration ICP above below treatment thresholds calculated as "pressure times time dose" (PTD; mm Hg . h) using recordings (PTDa) or manual...
Brenner, Megan MD, MS; Stein, Deborah M. MPH; Hu, Peter F. Aarabi, Bizhan MD; Sheth, Kevin Scalea, Thomas MD
Anomaly detection (AD) requires spectral and spatial information to differentiate anomalies from their surrounding data samples. To capture information, a general approach is utilize local windows in various forms adapt characteristics of the background (BKG) which unknown can be detected. This article develops new approach, called iterative spectral–spatial hyperspectral AD (ISSHAD), improve an anomaly detector its performance via process. Its key idea include process that captures maps...
Due to significant inter-band correlation resulting from the use of hundreds contiguous spectral bands, band selection (BS) is commonly used reduce data dimensionality for redundancy removal. A challenge BS how design an effective criterion which can select bands with crucial self-retained information, while also avoiding highly correlated be selected. This article presents a novel approach, referred as self-mutual information-based (SMI-BS) hyperspectral image classification (HSIC) address...
Calculation of integer heart rate variability (HRVi) permits monitoring over extended periods. We asked whether continuous HRVi or pulse pressure (PP) (PPVi) could predict intracranial hypertension, defined as ICP >20 mm Hg, cerebral hypoperfusion, CPP<60 mortality functional outcome after severe traumatic brain injury. Dense data collected during intensive care unit for periods 1 to 11 days on 25 patients admitted our Level I trauma center with Glasgow Coma Scale <9 provided 1,715,000...
Cortical neural dynamics mediate information processing for the cerebral cortex, which is implicated in fundamental biological processes such as vision and olfaction, addition to neurological psychiatric diseases. Spontaneous pain a key feature of human neuropathic pain. Whether spontaneous pushes cortical network into an aberrant state and, if so, whether it can be brought back “normal” operating range ameliorate are unknown. Using clinically relevant mouse model with pain–like behavior, we...
Open chest cardiac massage (OCCM) is a commonly performed procedure after traumatic arrest (TCA). OCCM has been reported to be superior closed compressions (CCC) in animal models and non-TCA. The purpose of this study prospectively compare versus CCC TCA using end-tidal carbon dioxide (ETCO2), the criterion standard for determining effectiveness detection return spontaneous circulation (ROSC), as surrogate output marker adequacy resuscitation.This prospective observational enrolled patients...
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a torso hemorrhage control adjunct. Aortic branch vessel flow (BVF) during REBOA poorly characterized and has implications for ischemia-reperfusion injury. The aim this study to quantify BVF in hypovolemic shock with without REBOA.Female swine (79-90 kg) underwent anesthesia, 40% controlled sonographic monitoring carotid, hepatic, superior mesenteric, renal, femoral arteries. Animals were randomized (n = 5) or no-REBOA 4...
Recognizing the use of uncross-matched packed red blood cells (UnXRBCs) or predicting need for massive transfusion (MT) in injured patients with hemorrhagic shock can be challenging.A validated predictive model could accelerate decision making regarding transfusion.Three outcomes were evaluated adult trauma admitted to a Level I center during 4-year period (2009-2012): UnXRBC, greater than 4 U within hours (MT1), and equal 10 24 (MT2). Vital sign (VS) features including heart rate, systolic...
Gaussian pyramid (GP) is a commonly used image coding technique which encodes an as stacked by set of images with window-reduced sizes and multiple spatial resolutions. Associated GP Laplacian (LP) can be also constructed to represent differential between in two consecutive layers GP. Such resulting Gaussian-Laplacian (GLP) performs data compression lossless lossy manner. A convolutional neural network (CNN) consists series concatenated feedforward manner where each layer has sublayer (CL)...
We developed an algorithm for processing networked vital signs (VS) to remotely identify in real-time when a patient enters and leaves given operating room (OR). The addresses two types of mismatches between OR occupancy VS: is the but no VS are available (e.g., being hooked up), artifactual present because staff handling sensors). was with data from 7 consecutive days (122 cases) 6 trauma center. then tested on another (98 cases), against in- out-times captured by surveillance videos. When...
Cardiac dysfunction is frequently observed after severe traumatic brain injury (sTBI); however, its significance poorly understood. Our study sought to elucidate the association of cardiac troponin I (cTnI) elevation with all-cause in-hospital mortality following isolated sTBI (brain Abbreviated Injury Scale score ≥3 and admission Glasgow Coma ≤8, no any other bodily regions).We retrospectively reviewed all adult patients (aged ≥18 years) admitted a Level trauma center between June 2007...