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Jonathan J. Morrison

ORCID: 0000-0001-7462-8456
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A5045688701
Research Areas
  • Trauma and Emergency Care Studies
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Cardiac Arrest and Resuscitation
  • Vascular Procedures and Complications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Pelvic and Acetabular Injuries
  • Abdominal Trauma and Injuries
  • Trauma Management and Diagnosis
  • Aortic Disease and Treatment Approaches
  • BRCA gene mutations in cancer
  • Peripheral Artery Disease Management
  • Genetic Associations and Epidemiology
  • Venous Thromboembolism Diagnosis and Management
  • Aortic aneurysm repair treatments
  • Pregnancy and preeclampsia studies
  • Injury Epidemiology and Prevention
  • Hemodynamic Monitoring and Therapy
  • Mechanical Circulatory Support Devices
  • Nutrition, Genetics, and Disease
  • Cardiac, Anesthesia and Surgical Outcomes
  • Acute Ischemic Stroke Management
  • Emergency and Acute Care Studies
  • Cerebrovascular and Carotid Artery Diseases
  • Folate and B Vitamins Research
  • Traumatic Ocular and Foreign Body Injuries

Mayo Clinic in Arizona
 2022-2025

University Hospital Galway
 2001-2025

Ollscoil na Gaillimhe – University of Galway
 2002-2025

Mayo Clinic
 2022-2024

Johns Hopkins University
 2021-2024

University of Maryland, Baltimore
 2017-2023

University of Maryland Medical System
 2017-2023

Cancer Research UK
 2008-2023

University of Cambridge
 1994-2023

WinnMed
 2022-2023

 Genome-wide association study identifies novel breast cancer susceptibility loci
OPENALEX - Publications 
Douglas F. Easton Karen A. Pooley Alison M. Dunning Paul D.P. Pharoah Deborah J. Thompson and 95 more Dennis G. Ballinger Jeffery P. Struewing Jonathan J. Morrison Helen I. Field Robert Luben Nicholas J. Wareham Shahana Ahmed Catherine S. Healey Richard Bowman Craig Luccarini Don Conroy Mitul Shah Hannah Munday Clare Jordan Barbara Perkins Judy West Karen Redman Kristy Driver Kerstin B. Meyer Christopher A. Haiman Laurence Kolonel Brian E. Henderson Loı̈c Le Marchand Paul Brennan Suleeporn Sangrajrang Valérie Gaborieau Fabrice Odefrey Chen‐Yang Shen Pei‐Ei Wu Hui‐Chun Wang Diana Eccles D. Gareth Evans Julian Peto Olivia Fletcher Nichola Johnson Sheila Seal Michael R. Stratton Nazneen Rahman Georgia Chenevix‐Trench Stig E. Bojesen Børge G. Nordestgaard C. K. Axelsson Montserrat García‐Closas Louise A. Brinton Stephen J. Chanock Jolanta Lissowska Beata Pepłońska Heli Nevanlinna Rainer Fagerholm Hannaleena Eerola Daehee Kang Keun-Young Yoo Dong‐Young Noh Sei Hyun Ahn David J. Hunter Susan E. Hankinson David G. Cox Per Hall Sara Wedrén Jianjun Liu Yen-Ling Low Natalia Bogdanova Peter Schürmann Thilo Dörk Rob A.�E.�M. Tollenaar Catharina E. Jacobi Peter Devilee Jan G.M. Klijn Alice J. Sigurdson Michele M. Doody Bruce H. Alexander Jinghui Zhang Angela Cox Ian W. Brock Gordon R. Macpherson Malcolm Reed Fergus J. Couch Ellen L. Goode Janet E. Olson Hanne Meijers‐Heijboer Ans van den Ouweland André G. Uitterlinden Fernando Rivadeneira Roger L. Milne Glòria Ribas Anna González‐Neira Javier Benı́tez John L. Hopper Margaret McCredie Melissa C. Southey Graham G. Giles Chris Schroen Christina Justenhoven Hiltrud Brauch Ute Hamann

10.1038/nature05887 article EN Nature 2007-05-27
 Multiple newly identified loci associated with prostate cancer susceptibility
OPENALEX - Publications 
Rosalind A. Eeles Zsofia Kote‐Jarai Graham G. Giles Ali Amin Al Olama Michelle Guy and 41 more Sarah Jugurnauth S. Grant Mulholland Daniel Leongamornlert Stephen M. Edwards Jonathan J. Morrison Helen I. Field Melissa C. Southey Gianluca Severi Jenny Donovan Freddie C. Hamdy David Dearnaley Kenneth Muir Charmaine Smith Melisa Bagnato Audrey Ardern‐Jones Amanda L. Hall Lynne T. O'Brien Beatrice N. Gehr-Swain Rosemary Wilkinson Angela Cox Sarah J. Lewis Paul Brown Sameer Jhavar Malgorzata Tymrakiewicz Artitaya Lophatananon Sarah L. Bryant Alan Horwich Robert Huddart Vincent Khoo Christopher Parker Christopher Woodhouse Alan J. Thompson Tim Christmas Chris Ogden Cyril Fisher Charles Jamieson Colin S. Cooper Dallas R. English John L. Hopper David E. Neal Douglas F. Easton

10.1038/ng.90 article EN Nature Genetics 2008-02-10
 A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
OPENALEX - Publications 
Paul I. W. de Bakker Gil McVean Pardis C. Sabeti Marcos Miretti Todd J. Green and 24 more Jonathan Marchini Xiayi Ke Alienke J. Monsuur Pamela Whittaker Marcos Delgado Jonathan J. Morrison Angela M. Richardson Emily C. Walsh Xiaojiang Gao Luana Galver John Hart David A. Hafler Margaret A. Pericak‐Vance John A. Todd Mark Daly John Trowsdale Cisca Wijmenga Tim J. Vyse Stephan Beck Sarah S. Murray Mary Carrington Simon G. Gregory Panos Deloukas John D. Rioux

10.1038/ng1885 article EN Nature Genetics 2006-09-24
 Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study
OPENALEX - Publications 
Jonathan J. Morrison

Objectives: To characterize contemporary use of tranexamic acid (TXA) in combat injury and to assess the effect its administration on total blood product use, thromboembolic complications, mortality.Design: Retrospective observational study comparing TXA with no patients receiving at least 1 unit packed red cells.A subgroup massive transfusion (Ն10 units cells) was also examined.Univariate multivariate regression analyses were used identify parameters associated survival.Kaplan-Meier life...

10.1001/archsurg.2011.287 article EN Archives of Surgery 2011-10-18
 Genome-wide association study identifies five new breast cancer susceptibility loci
OPENALEX - Publications 
Clare Turnbull Shahana Ahmed Jonathan J. Morrison David Pernet Anthony Renwick and 21 more Mel Maranian Sheila Seal Maya Ghoussaini Sarah Hines Catherine S. Healey Deborah Hughes Margaret Warren-Perry William Tapper Diana Eccles D. Gareth Evans Maartje J. Hooning Mieke Schutte Ans van den Ouweland Richard S. Houlston Gillian Ross Cordelia Langford Paul D.P. Pharoah Michael R. Stratton Alison M. Dunning Nazneen Rahman Douglas F. Easton

10.1038/ng.586 article EN Nature Genetics 2010-05-09
 Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2
OPENALEX - Publications 
Shahana Ahmed Gilles Thomas Maya Ghoussaini Catherine S. Healey Manjeet K. Humphreys and 95 more Radka Platte Jonathan J. Morrison Melanie Maranian Karen A. Pooley Robert Luben Diana Eccles D. Gareth Evans Olivia Fletcher Nichola Johnson Isabel dos‐Santos‐Silva Julian Peto Michael R. Stratton Nazneen Rahman Kevin B. Jacobs Ross L. Prentice Garnet L. Anderson Aleksandar Rajkovic J. David Curb Regina G. Ziegler Christine D. Berg Saundra S. Buys Catherine A. McCarty Heather Spencer Feigelson Eugenia E. Calle Michael J. Thun W. Ryan Diver Stig E. Bojesen Børge G. Nordestgaard Henrik Flyger Thilo Dörk Peter Schürmann Peter Hillemanns Johann H. Karstens Natalia Bogdanova Natalia Antonenkova Iosif V. Zalutsky Marina Bermisheva С.А. Федорова Э. К. Хуснутдинова Daehee Kang Keun-Young Yoo Dong‐Young Noh Sei-Hyun Ahn Peter Devilee Christi J. van Asperen Robert A.E.M. Tollenaar Caroline Seynaeve Montserrat García‐Closas Jolanta Lissowska Louise A. Brinton Beata Pepłońska Heli Nevanlinna Tuomas Heikkinen Kristiina Aittomäki Carl Blomqvist John L. Hopper Melissa C. Southey Letitia Smith Amanda B. Spurdle Marjanka K. Schmidt Annegien Broeks Richard R van Hien Sten Cornelissen Roger L. Milne Glòria Ribas Anna González‐Neira Javier Benı́tez Rita K. Schmutzler Barbara Burwinkel Claus R. Bartram Alfons Meindl Hiltrud Brauch Christina Justenhoven Ute Hamann Jenny Chang‐Claude Rebecca Hein Shan Wang‐Gohrke Annika Lindblom Sara Margolin Graham J. Mann Veli-Matti Kosma Vesa Kataja Janet E. Olson Xianshu Wang Zachary Fredericksen Graham G. Giles Gianluca Severi Laura Baglietto Dallas R. English Susan E. Hankinson David G. Cox Peter Kraft Lars J. Vatten Kristian Hveem Merethe Kumle

10.1038/ng.354 article EN Nature Genetics 2009-03-29
 Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
OPENALEX - Publications 
Rosalind A. Eeles Zsofia Kote‐Jarai Ali Amin Al Olama Graham G. Giles Michelle Guy and 95 more Gianluca Severi Kenneth Muir John L. Hopper Brian E. Henderson Christopher A. Haiman Johanna Schleutker Freddie C. Hamdy David E. Neal Jenny Donovan Janet L. Stanford Elaine A. Ostrander Sue A. Ingles Esther M. John Stephen N. Thibodeau Daniel J. Schaid Jong Y. Park Amanda B. Spurdle Judith A. Clements Joanne L. Dickinson Christiane Maier Walther Vogel Thilo Dörk Timothy R. Rebbeck Kathleen A. Cooney Lisa Cannon‐Albright Pierre O. Chappuis Pierre Hutter Maurice P. Zeegers Radka Kaneva Hongwei Zhang Yong‐Jie Lu William D. Foulkes Dallas R. English Daniel Leongamornlert Malgorzata Tymrakiewicz Jonathan J. Morrison Audrey Ardern‐Jones Amanda L. Hall Lynne T. O'Brien Rosemary Wilkinson Edward J. Saunders Elizabeth Page Emma J Sawyer Stephen M. Edwards David P. Dearnaley Alan Horwich Robert Huddart Vincent Khoo Christopher Parker Nicholas van As Christopher Woodhouse Alan Thompson Tim Christmas Chris Ogden Colin S. Cooper Melissa C. Southey Artitaya Lophatananon Jo‐Fen Liu Laurence N. Kolonel Loı̈c Le Marchand Tiina Wahlfors Teuvo L.J. Tammela Anssi Auvinen Sarah J. Lewis Angela Cox Liesel M. FitzGerald Joseph S. Koopmeiners Danielle M. Karyadi Erika M. Kwon Mariana C. Stern Román Corral Amit D. Joshi Ahva Shahabi Shannon K. McDonnell Thomas A. Sellers Julio M. Pow‐Sang Suzanne K. Chambers Joanne F. Aitken Robert A. Gardiner Jyotsna Batra Mary Anne Kedda Felicity Lose Andrea Polanowski Briony Patterson Jürgen Serth Andreas Meyer Manuel Luedeke Klara Stefflova Anna M. Ray Ethan M. Lange James M. Farnham Humera Khan Chavdar Slavov A. Mitkova Guangwen Cao

10.1038/ng.450 article EN Nature Genetics 2009-09-20
 Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics
OPENALEX - Publications 
Montserrat García‐Closas Per Hall Heli Nevanlinna Karen A. Pooley Jonathan J. Morrison and 95 more Douglas Richesson Stig E. Bojesen Børge G. Nordestgaard C. K. Axelsson José Ignacio Arias Roger L. Milne Glòria Ribas Anna González‐Neira Javier Benı́tez Pilar Zamora Hiltrud Brauch Christina Justenhoven Ute Hamann Yon‐Dschun Ko Thomas Bruening Susanne Haas Thilo Dörk Peter Schürmann Peter Hillemanns Natalia Bogdanova Michael Bremer Johann H. Karstens Rainer Fagerholm Kirsimari Aaltonen Kristiina Aittomäki Karl von Smitten Carl Blomqvist Graham J. Mann Matti Uusitupa Matti Eskelinen Maria Tengström Veli‐Matti Kosma Vesa Kataja Georgia Chenevix‐Trench Amanda B. Spurdle Jonathan Beesley Xiaohong Chen Peter Devilee Christi J. van Asperen Catharina E. Jacobi Rob A.�E.�M. Tollenaar Petra E.A. Huijts Jan G.M. Klijn Jenny Chang‐Claude Silke Kropp Tracy Slanger Dieter Flesch‐Janys Elke Mutschelknauss Ramona Salazar Shan Wang‐Gohrke Fergus J. Couch Ellen L. Goode Janet E. Olson Celine M. Vachon Zachary S. Fredericksen Graham G. Giles Laura Baglietto Gianluca Severi John L. Hopper Dallas R. English Melissa C. Southey Christopher A. Haiman Brian E. Henderson Laurence N. Kolonel Loı̈c Le Marchand Daniel O. Stram David J. Hunter Susan E. Hankinson David G. Cox Rulla M. Tamimi Peter Kraft Mark E. Sherman Stephen J. Chanock Jolanta Lissowska Louise A. Brinton Beata Pepłońska Jan G.M. Klijn Maartje J. Hooning Han Meijers-Heijboer J. Margriet Collée Ans van den Ouweland André G. Uitterlinden Jianjun Liu Low Yen Lin Yuqing Li Keith Humphreys Kamila Czene Angela Cox Sabapathy P. Balasubramanian Simon S. Cross Malcolm Reed Fiona M. Blows Kristy Driver Alison M. Dunning Jonathan P. Tyrer

A three-stage genome-wide association study recently identified single nucleotide polymorphisms (SNPs) in five loci (fibroblast growth receptor 2 (FGFR2), trinucleotide repeat containing 9 (TNRC9), mitogen-activated protein kinase 3 K1 (MAP3K1), 8q24, and lymphocyte-specific 1 (LSP1)) associated with breast cancer risk. We investigated whether the associations between these SNPs risk varied by clinically important tumor characteristics up to 23,039 invasive cases 26,273 controls from 20...

10.1371/journal.pgen.1000054 article EN cc-by PLoS Genetics 2008-04-25
 A genome-wide association study of testicular germ cell tumor
OPENALEX - Publications 
Elizabeth Rapley Clare Turnbull Ali Amin Al Olama Emmanouil T. Dermitzakis Rachel Linger and 12 more Robert Huddart Anthony Renwick Deborah Hughes Sarah Hines Sheila Seal Jonathan J. Morrison Jérémie Nsengimana Panos Deloukas Nazneen Rahman D. Timothy Bishop Douglas F. Easton Michael R. Stratton

10.1038/ng.394 article EN Nature Genetics 2009-05-31
 A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population
OPENALEX - Publications 
Antonis C. Antoniou Xianshu Wang Zachary S Fredericksen Lesley McGuffog Robert F. Tarrell and 95 more Olga M. Sinilnikova Sue Healey Jonathan J. Morrison Christiana Kartsonaki Timothy G. Lesnick Maya Ghoussaini Daniel Barrowdale Susan Peock Margaret Cook Clare Oliver Debra Frost Diana Eccles D. Gareth Evans Rosalind A. Eeles Louise Izatt Carol Chu Fiona Douglas J. Paterson Dominique Stoppa-Lyonnet Claude Houdayer Sylvie Mazoyer Sophie Giraud Christine Lasset Audrey Remenieras Olivier Caron Agnès Hardouin Pascaline Berthet Frans B.L. Hogervorst Matti A. Rookus Agnes Jager Ans van den Ouweland Nicoline Hoogerbrugge Rob B. van der Luijt Hanne Meijers‐Heijboer E. Gómez Peter Devilee Maaike P.G. Vreeswijk Jan Lubiński Anna Jakubowska Jacek Gronwald Tomasz Huzarski Tomasz Byrski Bohdan Górski Cezary Cybulski Amanda B. Spurdle Helene Holland David E. Goldgar Esther M. John John L. Hopper Melissa C. Southey Saundra S. Buys Mary B. Daly Mary Beth Terry Rita K. Schmutzler Barbara Wappenschmidt Christoph Engel Alfons Meindl Sabine Preisler‐Adams Norbert Arnold Dieter Niederacher Christian Sutter Susan M. Domchek Katherine L. Nathanson Timothy R. Rebbeck Joanne L. Blum Marion Piedmonte Gustavo C. Rodriguez Katie Wakeley John F. Boggess Jack Basil Stephanie V. Blank Eitan Friedman Bella Kaufman Yael Laitman Roni Milgrom Irene L. Andrulis Gord Glendon Hilmi Özçelik Tomas Kirchhoff Joseph Vijai Mia M. Gaudet David Altshuler Candace Guiducci Niklas Loman Katja Harbst Johanna Rantala Hans Ehrencrona Anne–Marie Gerdes Mads Thomassen Lone Sunde Paolo Peterlongo Siranoush Manoukian Bernardo Bonanni Alessandra Viel Paolo Radice

10.1038/ng.669 article EN Nature Genetics 2010-09-19
 Multiple Loci With Different Cancer Specificities Within the 8q24 Gene Desert
OPENALEX - Publications 
Maya Ghoussaini Honglin Song Thibaud Koessler Ali Amin Al Olama Zsofia Kote‐Jarai and 28 more Kristy Driver Karen A. Pooley Susan J. Ramus Susanne K. Kjær Estrid Høgdall Richard A. DiCioccio Alice S. Whittemore Simon A. Gayther Graham G. Giles Michelle Guy Stephen M. Edwards Jonathan J. Morrison Jenny Donovan Freddie C. Hamdy David Dearnaley Audrey Ardern‐Jones Amanda L. Hall Lynne T. O'Brien Beatrice N. Gehr-Swain Rosemary Wilkinson Paul Brown John L. Hopper David E. Neal Paul D.P. Pharoah Bruce A.J. Ponder Rosalind A. Eeles Douglas F. Easton Alison M. Dunning

Recent studies based on genome-wide association, linkage, and admixture scan analysis have reported associations of various genetic variants in 8q24 with susceptibility to breast, prostate, colorectal cancer. This locus lies within a 1.18-Mb region that contains no known genes but is bounded at its centromeric end by FAM84B telomeric c-MYC, two candidate cancer genes. To investigate the specific loci cancers, we genotyped nine previously cancer-associated single-nucleotide polymorphisms...

10.1093/jnci/djn190 article EN JNCI Journal of the National Cancer Institute 2008-06-24
 Multiple loci on 8q24 associated with prostate cancer susceptibility
OPENALEX - Publications 
Ali Amin Al Olama Zsofia Kote‐Jarai Graham G. Giles Michelle Guy Jonathan J. Morrison and 30 more Gianluca Severi Daniel Leongamornlert Malgorzata Tymrakiewicz Sameer Jhavar Edward J. Saunders John L. Hopper Melissa C. Southey Kenneth Muir Dallas R. English David P. Dearnaley Audrey Ardern‐Jones Amanda L. Hall Lynne T. O'Brien Rosemary Wilkinson Emma Sawyer Artitaya Lophatananon Alan Horwich Robert Huddart Vincent Khoo Christopher Parker Christopher Woodhouse Alan Thompson Tim Christmas Chris Ogden Colin Cooper Jenny Donovan Freddie C. Hamdy David E. Neal Rosalind A. Eeles Douglas F. Easton

10.1038/ng.452 article EN Nature Genetics 2009-09-20
 Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
OPENALEX - Publications 
Zsofia Kote‐Jarai Ali Amin Al Olama Graham G. Giles Gianluca Severi Johanna Schleutker and 95 more Maren Weischer Daniele Campa Elio Ríboli Timothy J. Key Henrik Grönberg David J. Hunter Peter Kraft Michael J. Thun Sue A. Ingles Stephen Chanock Demetrius Albanes Richard B. Hayes David E. Neal Freddie C. Hamdy Jenny Donovan Paul D.P. Pharoah Fredrick R. Schumacher Brian E. Henderson Janet L. Stanford Elaine A. Ostrander Karina D. Sørensen Thilo Dörk Gerald L. Andriole Joanne L. Dickinson Cezary Cybulski Jan Lubiński Amanda B. Spurdle Judith A. Clements Suzanne K. Chambers Joanne F. Aitken Robert A. Gardiner Stephen N. Thibodeau Dan Schaid Esther M. John Christiane Maier Walther Vogel Kathleen A. Cooney Jong Y. Park Lisa Cannon‐Albright Hermann Brenner Tomonori Habuchi Hongwei Zhang Yong‐Jie Lu Radka Kaneva Ken Muir Sara Benlloch Daniel Leongamornlert Edward J. Saunders Malgorzata Tymrakiewicz Nadiya Mahmud Michelle Guy Lynne T. O'Brien Rosemary Wilkinson Amanda L. Hall Emma J Sawyer Tokhir Dadaev Jonathan J. Morrison David P. Dearnaley A. Horwich Robert Huddart Vincent Khoo Christopher Parker Nicholas van As Christopher Woodhouse Alan Thompson Tim Christmas Chris Ogden Colin S. Cooper Aritaya Lophatonanon Melissa C. Southey John L. Hopper Dallas R. English Tiina Wahlfors Teuvo L.J. Tammela Peter Klarskov Børge G. Nordestgaard Martin Andreas Røder Anne Tybjærg‐Hansen Stig E. Bojesen Ruth C. Travis Federico Canzian Rudolf Kaaks Fredrik Wiklund Markus Aly Sara Lindström W. Ryan Diver Susan M. Gapstur Mariana C. Stern Román Corral Jarmo Virtamo Angela Cox Christopher A. Haiman Loı̈c Le Marchand Liesel M. FitzGerald Suzanne Kolb

10.1038/ng.882 article EN Nature Genetics 2011-07-10
 Emergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients With Exsanguinating Hemorrhage
OPENALEX - Publications 
Jan O. Jansen Jemma Hudson Claire Cochrane Graeme MacLennan Robbie Lendrum and 37 more Sam Sadek Katie Gillies Seonaidh Cotton Charlotte Kennedy Dwayne Boyers Gillian Ferry Louisa Lawrie Mintu Nath Samantha Wileman Mark Forrest Karim Brohi Tim Harris Fiona Lecky Chris Moran Jonathan J. Morrison John Norrie Alan Paterson Nigel Tai Nick Welch Marion Campbell Christopher Aylwin Duncan Bew Adam Brooks James Chinery Tom Cowlam Dan Frith Arun George Anthony Hudson Phillip Johnstone Ansar Mahmood Alex Novak Matt O’Meara S. Reid Abdo Sattout Chris Smith Tim Stansfield Julian R. Thompson

Bleeding is the most common cause of preventable death after trauma.

10.1001/jama.2023.20850 article EN JAMA 2023-10-12
 A High-Resolution Linkage-Disequilibrium Map of the Human Major Histocompatibility Complex and First Generation of Tag Single-Nucleotide Polymorphisms
OPENALEX - Publications 
Marcos Miretti Emily C. Walsh Xiayi Ke Marcos Delgado Mark Griffiths and 9 more Sarah Hunt Jonathan J. Morrison Pamela Whittaker Eric S. Lander Lon R. Cardon David Bentley John D. Rioux Stephan Beck Panos Deloukas

10.1086/429393 article EN publisher-specific-oa The American Journal of Human Genetics 2005-03-29
 Association of Cryoprecipitate and Tranexamic Acid With Improved Survival Following Wartime Injury
OPENALEX - Publications 
Jonathan J. Morrison James D. Ross Joseph J. DuBose Jan O. Jansen Mark J. Midwinter and 1 more Todd E. Rasmussen

To quantify the impact of fibrinogen-containing cryoprecipitate in addition to antifibrinolytic tranexamic acid on survival combat injured.Retrospective observational study comparing mortality 4 groups: only, and cryoprecipitate, neither nor cryoprecipitate. balance comparisons, propensity scores were developed added as covariates logistic regression models predicting mortality.A Role 3 Combat Surgical Hospital southern Afghanistan.A total 1332 patients identified from prospectively...

10.1001/jamasurg.2013.764 article EN JAMA Surgery 2012-11-19
 Physiologic tolerance of descending thoracic aortic balloon occlusion in a swine model of hemorrhagic shock
OPENALEX - Publications 
Nickolay P. Markov Thomas Percival Jonathan J. Morrison James D. Ross Daniel Scott and 2 more Jerry R. Spencer Todd E. Rasmussen

10.1016/j.surg.2012.12.001 article EN Surgery 2013-02-27
 Epidemiology and outcomes of non-compressible torso hemorrhage
OPENALEX - Publications 
Mehreen Kisat Jonathan J. Morrison Zain G. Hashmi David T. Efron Todd E. Rasmussen and 1 more Adil H. Haider

10.1016/j.jss.2013.05.099 article EN Journal of Surgical Research 2013-06-21
 Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer
OPENALEX - Publications 
Mia M. Gaudet Tomas Kirchhoff Todd Green Joseph Vijai Joshua M. Korn and 95 more Candace Guiducci Ayellet V. Segrè Kate McGee Lesley McGuffog Christiana Kartsonaki Jonathan J. Morrison Sue Healey Olga M. Sinilnikova Dominique Stoppa‐Lyonnet Sylvie Mazoyer Marion Gauthier‐Villars Hagay Sobol Michel Longy Marc Frénay GEMO Study Collaborators Frans B. L. Hogervorst Matti A. Rookus J. Margriet Collée Nicoline Hoogerbrugge Kees E. P. van Roozendaal Marion Piedmonte Wendy Rubinstein Stacy Nerenstone Linda Van Le Stephanie V. Blank Trinidad Caldés Miguel de la Hoya Heli Nevanlinna Kristiina Aittomäki Conxi Lázaro Ignacio Blanco Aðalgeir Arason Oskar T. Johannsson Rósa B. Barkardóttir Peter Devilee O. I. Olopade Susan L. Neuhausen Xianshu Wang Zachary S. Fredericksen Paolo Peterlongo Siranoush Manoukian Monica Barile Alessandra Viel Paolo Radice Catherine M. Phelan Steven Narod Gad Rennert Flavio Lejbkowicz Anath Flugelman Irene L. Andrulis Gord Glendon Hilmi Özçelik Amanda E. Toland Marco Montagna Emma D’Andrea Eitan Friedman Yael Laitman Åke Borg Mary Beattie Susan J. Ramus Susan M. Domchek Katherine L. Nathanson Tim Rebbeck Amanda B. Spurdle Xiaohong Chen Helene Holland Esther M. John John L. Hopper Saundra S. Buys Mary B. Daly Melissa C. Southey Mary Beth Terry Nadine Tung Thomas van Overeem Hansen Finn Cilius Nielsen Mark I. Greene L. Phuong Ana Osório M. Durán Raquel Andrés Javier Benítez Jeffrey N. Weitzel Judy E. Garber Ute Hamann Susan Peock Margaret Cook Clare Oliver Debra Frost Radka Platte D. Gareth Evans Fiona Lalloo Rosalind A. Eeles Louise Izatt Lisa Walker Jacqueline Eason

The considerable uncertainty regarding cancer risks associated with inherited mutations of BRCA2 is due to unknown factors. To investigate whether common genetic variants modify penetrance for mutation carriers, we undertook a two-staged genome-wide association study in carriers. In stage 1 using the Affymetrix 6.0 platform, 592,163 filtered SNPs genotyped were available on 899 young (<40 years) affected and 804 unaffected carriers European ancestry. Associations evaluated survival-based...

10.1371/journal.pgen.1001183 article EN cc-by PLoS Genetics 2010-10-28
 Genome-wide association study identifies a common variant associated with risk of endometrial cancer
OPENALEX - Publications 
Amanda B. Spurdle Deborah J. Thompson Shahana Ahmed Kaltin Ferguson Catherine S. Healey and 45 more Tracy A. O’Mara Logan C. Walker Stephen B. Montgomery Emmanouil T. Dermitzakis Paul Fahey Grant W. Montgomery Penelope M. Webb Peter A. Fasching Matthias W. Beckmann Arif B. Ekici Alexander Hein Diether Lambrechts Lieve Coenegrachts Ignace Vergote Frédéric Amant Helga B. Salvesen Jone Trovik Tormund S. Njølstad Harald Helland Rodney J. Scott Katie A. Ashton Tony Proietto Geoffrey Otton Ian Tomlinson Maggie Gorman Kimberley Howarth Shirley Hodgson Montserrat García‐Closas Nicolas Wentzensen Hannah Yang Stephen J. Chanock Per Hall Kamila Czene Jianjun Liu Jingmei Li Xiao‐Ou Shu Wei Zheng Jirong Long Yong‐Bing Xiang Mitul Shah Jonathan J. Morrison Kyriaki Michailidou Paul D.P. Pharoah Alison M. Dunning Douglas F. Easton

10.1038/ng.812 article EN Nature Genetics 2011-04-17
 En-Route Care Capability From Point of Injury Impacts Mortality After Severe Wartime Injury
OPENALEX - Publications 
Jonathan J. Morrison John S. Oh Joseph J. DuBose David O’Reilly Robert Rußell and 3 more Lorne H. Blackbourne Mark J. Midwinter Todd E. Rasmussen

The objective of this study is to characterize modern point-of-injury (POI) en-route care platforms and compare mortality among casualties evacuated with conventional military retrieval (CMR) methods those an advanced medical (AMR) capability.Following a decade war in Afghanistan, the impact capabilities from POI on unknown.Casualties one level III facility Afghanistan (July 2008-March 2012) were identified UK US trauma registries. Groups comprised by medically qualified provider-led, AMR...

10.1097/sla.0b013e31827eefcf article EN Annals of Surgery 2013-01-04
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