A5005903368- Trauma and Emergency Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Non-Invasive Vital Sign Monitoring
- Hemodynamic Monitoring and Therapy
- Heart Rate Variability and Autonomic Control
- Healthcare Technology and Patient Monitoring
- Traumatic Brain Injury Research
- Sepsis Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Emergency and Acute Care Studies
- Machine Learning in Healthcare
- Neurosurgical Procedures and Complications
- S100 Proteins and Annexins
- Sparse and Compressive Sensing Techniques
- Surgical Simulation and Training
- Trauma Management and Diagnosis
- Parallel Computing and Optimization Techniques
- Acute Ischemic Stroke Management
- Anatomy and Medical Technology
- Health Literacy and Information Accessibility
- Traffic Prediction and Management Techniques
- Medication Adherence and Compliance
- Anomaly Detection Techniques and Applications
University of Maryland, Baltimore
2016-2025
University of Mary
2025
Harbin Institute of Technology
2022-2023
State Council of the People's Republic of China
2020-2021
Maryland Medical Research Institute
2021
United States Air Force
2021
International Trauma Anesthesia and Critical Care Society
2019
University of Maryland Medical Center
2014-2018
Star Center
2018
Congressionally Directed Medical Research Programs
2018
<h3>Importance</h3> Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a percutaneous transfemoral technique used in select centers for resuscitation and temporary hemostasis, often instead emergency department thoracotomy. The ability to perform aortic (AO) with an intravascular device allows focused at most distal level perfuse proximal regions while slowing hemorrhage injured areas. <h3>Objective</h3> To describe what date largest single-institution experience REBOA...
With high spectral resolution hyperspectral imaging is capable of uncovering many subtle signal sources which cannot be known a priori or visually inspected. Such generally appear as anomalies in the data. Due to correlation among bands and sparsity anomalies, image can e decomposed into two subspaces: background subspace specified by matrix with low rank dimensionality an anomaly sparse dimensionality. This paper develops approach finding such low-high decomposition identify subspace. Its...
Road traffic sensors provide rich multivariable datastreams about the current conditions. Occasionally, there are unusual events (such as accidents, jams, and severe weather) that disrupt expected road Detecting occurrence of such in an online real-time manner is useful to drivers planning their routes management transportation infrastructure. We propose a new method for detecting impact conditions by extending Bayesian robust principal component analysis (RPCA) approach. Our couples...
Trauma remains a leading cause of morbidity and mortality in part due to secondary multi-organ injury. However, our ability predict the downstream pathophysiology adverse outcomes trauma is limited. Here, we select panel microRNAs (miRNAs) biomarker candidates based on plasma RNA-Seq analysis patients unique pro-inflammatory nucleotide motif structures identified via machine learning-guided computer exhaustive search algorithm. We test miRNAs for their association with various...
Health information technology has become common in the care of patients with chronic diseases; however, there are few such applications employed kidney disease.
Recognizing the use of uncross-matched packed red blood cells (UnXRBCs) or predicting need for massive transfusion (MT) in injured patients with hemorrhagic shock can be challenging.A validated predictive model could accelerate decision making regarding transfusion.Three outcomes were evaluated adult trauma admitted to a Level I center during 4-year period (2009-2012): UnXRBC, greater than 4 U within hours (MT1), and equal 10 24 (MT2). Vital sign (VS) features including heart rate, systolic...
Open chest cardiac massage (OCCM) is a commonly performed procedure after traumatic arrest (TCA). OCCM has been reported to be superior closed compressions (CCC) in animal models and non-TCA. The purpose of this study prospectively compare versus CCC TCA using end-tidal carbon dioxide (ETCO2), the criterion standard for determining effectiveness detection return spontaneous circulation (ROSC), as surrogate output marker adequacy resuscitation.This prospective observational enrolled patients...
No abstract available.
The accepted treatment of increased intracranial pressure (ICP) in patients experiencing severe traumatic brain injury is multimodal and algorithmic, obscuring individual effects treatment. Using continuous vital signs monitoring, we sought to measure effect ascertain the accuracy manual data recording.Patients older than 17 years, admitted requiring ICP monitoring between 2008 2010 at a high-volume urban trauma center, were retrospectively evaluated. Timing dose ICP-directed therapy...
BACKGROUND Secondary insults such as hypotension, hypoxia, cerebral hypoperfusion, and intracranial hypertension are associated with poor outcome following severe traumatic brain injury (TBI). Preventing minimizing the effect of secondary essential in management TBI. At present, clinicians have no way to predict development these events, limiting their ability plan appropriate timing interventions. We hypothesized that processing continuous vital signs (VS) data using machine learning...
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a temporizing maneuver used to decrease hemorrhage, and thus perfusion, below level aortic (AO). We sought investigate lower extremity ischemia in patients who received REBOA. Between February 2013 September 2016 at tertiary center that REBOA survived more than six hours were enrolled. Thirty-one identified, mean ISS was 40 ± 14 inhospital mortality 39 per cent. Twenty zone 1 (distal thoracic aorta). Three (15%) developed...
Secondary neurologic decline (ND) after traumatic brain injury (TBI) is independently associated with outcome, but robust predictors of ND are lacking. In this retrospective analysis consecutive isolated TBI admissions to the R. Adams Cowley Shock Trauma Center between November 2015 and June 2018, we aimed develop a triage decision support tool quantify risk for early ND. Three machine learning models based on clinical, physiologic, or combined characteristics from first hour hospital...
Summary Background and objectives Web-based technology is critical to the future of healthcare. As part Safe Kidney Care cohort study evaluating patient safety in CKD, this determined how effectively a representative sample patients with CKD or family members could interpret use website (www.safekidneycare.org), an informational on CKD. Design, setting, participants, & measurements Between November 2011 January 2012, persons their underwent formal usability testing administered by single...
Background: Intracranial hypertension (ICH) and hyperthermia are common after traumatic brain injury (TBI) associated with worse neurological outcomes. This study sets out to determine the combined power of temperature intracranial pressure (ICP) for predicting neurologic outcomes prolonged length stay (LOS) following severe TBI.Methods: High resolution (every 6 seconds) ICP data were collected in adults TBI from 2008–2010. Temperatures plotted against concurrent divided based on breakpoints...
Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) increases cardiac-afterload and is used for patients in hemorrhagic shock. The cardiac tolerance prolonged afterload augmentation this context unknown. aim study to quantify injury, if any, following 2, 3 4 hours REBOA.Anesthetized swine (70-90 kg) underwent a 40% controlled hemorrhage, followed by supraceliac resuscitative endovascular balloon occlusion aorta 2 (n=5), (n=5). High-fidelity arterial wave form data were...
Determination of prognosis in the triage process after traumatic brain injury (TBI) is difficult to achieve. Current severity measures like Trauma and score (TRISS) revised trauma (RTS) rely on additional information from Glasgow Coma Scale (GCS) Injury Severity Score (ISS) which may be inaccurate or delayed, limiting their usefulness rapid setting. We hypothesized that machine learning based estimations GCS ISS obtained through modeling continuous vital sign features could used rapidly...