A5027942445- Trauma and Emergency Care Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Abdominal Trauma and Injuries
- Pelvic and Acetabular Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Appendicitis Diagnosis and Management
- Abdominal Surgery and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Sepsis Diagnosis and Treatment
- Trauma Management and Diagnosis
- Venous Thromboembolism Diagnosis and Management
- Hernia repair and management
- Surgical Simulation and Training
- Disaster Response and Management
- Pleural and Pulmonary Diseases
- Heterotopic Ossification and Related Conditions
- Rheumatoid Arthritis Research and Therapies
- Innovations in Medical Education
- Pregnancy-related medical research
- Gallbladder and Bile Duct Disorders
- Nosocomial Infections in ICU
- Intraperitoneal and Appendiceal Malignancies
- Medical History and Innovations
- Surgical site infection prevention
Uniformed Services University of the Health Sciences
2014-2024
Brooke Army Medical Center
2020-2024
Joint Base San Antonio
2018-2024
William Beaumont Army Medical Center
2024
University of Miami Health System
2024
The Ohio State University
2024
The Ohio State University Wexner Medical Center
2024
Walter Reed National Military Medical Center
2015-2024
Womack Army Medical Center
2024
Royal Manchester Children's Hospital
2024
Enterocutaneous fistula (ECF), enteroatmospheric (EAF), and intra-abdominal sepsis/abscess (IAS) are major challenges for surgeons caring patients undergoing damage control laparotomy after trauma.To determine independent predictors of ECF, EAF, or IAS in trauma, using the AAST Open Abdomen Registry.The registry with an open abdomen following was used to identify who developed compare these those without complications. Univariate analyses were performed groups patients. Variables from...
Since publication of the CRASH-2 and MATTERs studies, US military has included tranexamic acid (TXA) in clinical practice guidelines. While TXA was shown to decrease mortality trauma patients requiring massive transfusion, improper administration increased risk venous thromboembolism remain a concern.To determine appropriateness by medical personnel based on current Joint Trauma System guidelines if is associated with thromboembolism.This cohort study casualties combat support hospitals...
For blunt trauma patients who have failed the NEXUS (National Emergency X-Radiography Utilization Study) low-risk criteria, adequacy of computed tomography (CT) as definitive imaging modality for clearance remains controversial. The purpose this study was to prospectively evaluate accuracy CT detection clinically significant cervical spine (C-spine) injury.This a prospective multicenter observational (September 2013 March 2015) at 18 North American centers. All adult (≥18 years old)...
Abstract Purpose of Review The purpose this review is to describe the advancements in combat casualty care from prehospital environment, through en route care, and into damage control resuscitative surgical during recent military conflict. We also explore potential areas future research needed enhance survivability on battlefield large-scale operations (LSCO). Recent Findings In space, use tourniquets has become standard practice for controlling severe hemorrhage, while techniques like...
Following spinal cord injury (SCI), neutrophils are the first peripheral immune cells to infiltrate injured in large numbers. There is a growing body of evidence demonstrating sex differences neutrophil function, however, role as biological variable response following SCI remain unclear. Additionally, while divergent roles for mature and immature subsets have been observed, subset-specific contributions functional recovery not fully characterized. Here, we provide novel that systemic...
Traumatic hemorrhage is the leading cause of preventable battlefield death and hemostatic agents can improve survival. We compared a novel, amorphous, silica dioxide-based fiber (SBF) matrix to criterion standard QuikClot Combat Gauze (QCCG) in treating junctional arterial injury hypocoagulable swine. Vascular access was obtained 16 anesthetized swine, hemodilution achieved with 50% blood exchange saline. A 5-mm arteriotomy made common femoral artery. After 30 seconds free bleeding, SBF or...
To investigate outpatient outcome measures of a multi-center, state-wide, universal newborn hearing screening project.Eight hospitals participated in 3-yr, funded project. Each hospital designed its own protocol using common criteria for judging whether an infant passed screening. Infants were tested the hospital, and those either failing in-hospital or who not (missed) asked to return 4 6 wk after discharge rescreening. Those infants rescreening referred diagnostic auditory brain stem...
Open chest cardiac massage (OCCM) is a commonly performed procedure after traumatic arrest (TCA). OCCM has been reported to be superior closed compressions (CCC) in animal models and non-TCA. The purpose of this study prospectively compare versus CCC TCA using end-tidal carbon dioxide (ETCO2), the criterion standard for determining effectiveness detection return spontaneous circulation (ROSC), as surrogate output marker adequacy resuscitation.This prospective observational enrolled patients...
Objective Resilience, the ability to recover from and adapt successfully stressful situations, is a valuable resource for patients who live with chronic conditions. This qualitative study examines development of resilience among rheumatoid arthritis (RA) patients. We aimed describe process strategies used by cultivate resilience. Methods Our approach combined ethnographic data collection narrative analysis methods. Semistructured interviews were conducted adult RA in US. Interviewees asked...
The biomarker profile of trauma patients may allow for the creation models to assist bedside decision making and prediction complications. We sought determine utility modeling in bacteremia pneumonia combat casualties.This is a prospective, observational trial with complex wounds treated at Walter Reed National Military Medical Center (2007-2012). Tissue, serum, wound effluent samples were collected during operative interventions until closure. Clinical, biomarker, outcome data used machine...
There exists a long established but not validated practice of placing temporary intravascular shunts (TIVS) in cases combined vascular and orthopedic extremity trauma. Though logical to prioritize blood flow, large-scale data support this is lacking. We hypothesize that the order repair yields no difference outcomes trauma offer larger-scale analysis than previously available.A retrospective chart review was conducted at six Level I centers from 2004 2015 comparing patients who received TIVS...
Traumatic heterotopic ossification (tHO) commonly develops in wounded service members who sustain high-energy and blast-related traumatic amputations. Currently, no safe effective preventive measures have been identified for this patient population. Bone morphogenetic protein (BMP) signaling blockade has previously shown to reduce ectopic bone formation genetic models of HO. In study, we demonstrate the efficacy small-molecule inhibition with LDN193189 (ALK2/ALK3 inhibition), LDN212854...
Abstract Controversy exists regarding the best diagnostic and screening tool for sepsis outside intensive care unit (ICU). Sequential organ failure assessment (SOFA) score has been shown to be superior systemic inflammatory response syndrome (SIRS) criteria, however, performance of “Red Flag criteria” not tested formally. The aim study was investigate ability Red criteria identify patients at high risk sepsis-related death in comparison SOFA based criteria. We also investigated quick...
OBJECTIVES The objective of this study is to describe the United States and allied military medical response during withdrawal from Afghanistan. BACKGROUND Afghanistan concluded with severe hostilities resulting in numerous civilian casualties. clinical care provided by coalition forces capitalized on decades lessons learned enabled unprecedented accomplishments. METHODS In retrospective, observational analysis, casualty numbers, operative information was collected reported assets Kabul,...
Although the use of damage control laparotomy (DCL) is well established, effect resuscitation (DCR) on management open abdomens relatively poorly studied. The aim present study was to determine predictors for failure achieve primary fascial closure (PFC) after DCL in setting a massive transfusion (MT) and DCR. This retrospective review over 12-year period all patients that underwent MT DCL. Patients who achieved PFC were compared with those did not (NPFC). Student's t tests used compare two...
The purpose of this study is to compare end-tidal carbon dioxide (EtCO 2 ) during resuscitation open-chest cardiac massage (OCCM) with aortic cross-clamp (ACC) versus receiving resuscitative endovascular balloon occlusion the aorta (REBOA) closed-chest compressions (CCCs). Patients who received REBOA were compared patients OCCM for traumatic arrest using continuous vital sign monitoring and videography. Thirty-three enrolled in group 18 group. Of total patients, 86.3 per cent male a mean age...
Beyond its anti-fibrinolytic mechanism, tranexamic acid has been suggested to have anti-inflammatory properties which may contribute the survival benefit it provides trauma patients. The objective of this study was assess possible immunomodulatory effects as well potential amelioration end-organ injury in a rodent hemorrhagic shock model. Controlled induced adult Sprague Dawley rats mean arterial pressure 30 mmHg. Groups 10 were administered intravenous (300mg/kg) or vehicle control (normal...