A5044624943- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Peripheral Artery Disease Management
- Neurosurgical Procedures and Complications
- Cardiac Arrest and Resuscitation
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury Research
- Renal and Vascular Pathologies
- Cerebral Venous Sinus Thrombosis
- Intensive Care Unit Cognitive Disorders
- Cerebrospinal fluid and hydrocephalus
Stony Brook School
2023-2025
Stony Brook University
2023-2025
University of Cincinnati Medical Center
2025
Massachusetts General Hospital
2024
Johns Hopkins University
2024
Rhode Island Hospital
2024
Cooper Medical School of Rowan University
2024
Johns Hopkins Hospital
2024
Johns Hopkins Medicine
2024
University of Cincinnati
2019-2024
Background Acute ischaemic stroke (AIS) is a leading cause of mortality and disability globally, with volume contracted state (VCS), as indicated by an elevated blood urea nitrogen to creatinine (BUN/Cr) ratio, potentially influencing outcomes. This study investigates the association between VCS clinical outcomes in patients AIS due large vessel occlusion (LVO). Methods A retrospective cohort was conducted involving 298 LVO-AIS from two comprehensive centres. Patients were divided into...
Abstract Objective Venous outflow (VO) impairment predicts unfavorable outcomes in patients with acute ischemic stroke caused by large vessel occlusion (AIS‐LVO). Prolonged venous transit (PVT), a visual qualitative VO marker on CT perfusion (CTP) time to maximum (Tmax) maps, has been associated 90‐day functional despite successful reperfusion. This study investigates the association between PVT and percent change National Institutes of Health Stroke Scale (NIHSS) among AIS‐LVO who have...
<h3>ABSTRACT</h3> <h3>BACKGROUND AND PURPOSE:</h3> Acute ischemic strokes caused by distal medium vessel occlusions (DMVO) represent a significant proportion of all stroke cases, yet the predictors excellent functional outcomes in these patients remain poorly understood. This study aims to identify pretreatment computed tomography perfusion (CTP) parameters associated with outcomes, defined as modified Rankin Scale (mRS) score 0-1 at 90 days, anterior circulation DMVO. <h3>MATERIALS...
ABSTRACT Background and purpose Prolonged length of stay (LOS) following a stroke is associated with unfavorable clinical outcomes. Factors predicting LOS in medium vessel occlusion (MeVO), impacting up to 40% acute ischemic (AIS) cases, remain underexplored. This study aims investigate the predictors AIS‐MeVO. Methods We conducted retrospective analysis prospectively maintained databases, comprising AIS cases MeVO anterior circulation, assessed by adequate CT perfusion (CTP). Baseline data...
Background and Purpose: Venous outflow (VO) impairment predicts unfavorable outcomes in patients with acute ischemic stroke caused by large vessel occlusion (AIS-LVO). Prolonged venous transit (PVT), a visual qualitative VO marker on CT perfusion (CTP) time to maximum (Tmax) maps, has been associated 90-day mortality despite successful reperfusion. This study investigates the association between PVT modified Rankin Scale (mRS) score at discharge among AIS-LVO who have undergone Methods: We...
Background and Purpose: Prolonged length of stay (LOS) following a stroke is associated with unfavorable clinical outcomes. Factors predicting LOS in medium vessel occlusion (MeVO), impacting up to 40% acute ischemic (AIS) cases, remain underexplored. This study aims investigate the predictors AIS-MeVO. Methods: We conducted retrospective analysis prospectively maintained databases, comprising AIS cases MeVO anterior circulation, assessed by adequate CT perfusion (CTP). Baseline data were...
Endovascular thrombectomy is a standard treatment for acute ischemic stroke due to large-vessel occlusions (AIS-LVO), but large minority of patients do not achieve successful reperfusion. This study aimed investigate the hypoperfusion intensity ratio (HIR) as prognostic biomarker in unsuccessfully reperfused with AIS-LVO. A multicenter retrospective cohort was conducted at 2 comprehensive centers, involving AIS-LVO who underwent endovascular did reperfusion, defined modified TICI score 0-2a....
Background Intracerebral hemorrhage (ICH) carries a 30‐day mortality rate of 40% to 50% and high burden disability. Prior studies found that psychosocial stressors are associated with hypertension, ischemic stroke, important racial/ethnic differences in baseline stress exist. We sought determine whether stress, including distinct subtypes, predicts risk ICH after controlling for factors; its effect is mediated by hypertension; stress‐associated Methods Data from the ERICH (Ethnic/Racial...
Background: The relative level of functional impairment in stroke patients is a significant determinant post-acute care. Activity Measure for Post Acute Care 6-Clicks (AM-PAC) scores basic mobility and daily activity are rapid standardized assessments whose utilities predicting long-term outcomes have not yet been studied. Methods: We performed retrospective analysis acute ischemic their outcomes. evaluated the distribution using chi-square test. then compared proportions with good different...
<h3>ABSTRACT</h3> <h3>BACKGROUND AND PURPOSE:</h3> Prolonged venous transit (PVT+) is a marker of outflow; it defined as the presence or absence time-to-maximum ≥10 seconds timing in either superior sagittal sinus torcula. This novel perfusion imaging-based metric has been associated with higher odds mortality and lower functional recovery. study aims to assess relationship between PVT on admission imaging length hospital stay large vessel occlusion strokes successfully reperfused mechanical...
Predicting severe traumatic brain injury (sTBI) outcomes is challenging, and existing models have limited applicability to individual patients. This study aimed identify metrics that could predict recovery following sTBI. The researchers strived demonstrate a posterior dominant rhythm on electroencephalography strongly associated with positive develop novel machine learning-based model accurately forecasts the return of consciousness.
Limited evidence is available for the treatment of acute symptomatic sub-occlusive lesions in ischemic stroke. We sought to identify current patterns stroke teams at academic health centers.
Introduction: Intracerebral hemorrhage (ICH) results in high mortality and rate of disability among survivors. The effects preexisting small vessel disease (SVD) on functional outcomes after ICH is uncertain understanding manifestations brain health such as white matter lesions (WML) atrophy are a top priority for developing prognostic indicators. Our objective was to determine whether WML associated with patients. Hypothesis: We hypothesized that higher burden will have poor outcome...
Background: Both intraventricular hemorrhage (IVH) and white matter lesion (WML) severity are associated with higher rates of death disability among cases intracerebral (ICH). Prior reports suggest WML burden is propensity IVH. However, those analyses were not stratified by location. Our objective was to investigate the hypothesis that a degree would be risk IVH after controlling for ICH Methods: The Genetic Environmental Risk Factors Hemorrhagic Stroke (GERFHS) III study prospective...