A5083113734- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Optical Coherence Tomography Applications
- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Antioxidant Activity and Oxidative Stress
- Ocular Surface and Contact Lens
- Cerebral Venous Sinus Thrombosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Intraocular Surgery and Lenses
- Scientific Measurement and Uncertainty Evaluation
- Advanced Measurement and Metrology Techniques
- Connexins and lens biology
- Ophthalmology and Eye Disorders
- Blood Pressure and Hypertension Studies
- Retinal Development and Disorders
- Photoacoustic and Ultrasonic Imaging
- Coronary Interventions and Diagnostics
- Health and Well-being Studies
- Advanced Fiber Optic Sensors
Austrian Center for Medical Innovation and Technology
2013-2020
Medical University of Vienna
2008-2012
Centre for Biomedical Engineering and Physics
2012
There is evidence from several large-scale clinical trials that reduced intake of lutein, a major component the macular pigment, risk factor for development AMD. In present study (LISA; Lutein Intervention Study Austria) it was hypothesized lutein supplementation increases pigment optical density (MPOD). addition, an investigation conducted into whether improves visual acuity (VA) and function (mean differential light threshold; MDLT), as assessed with microperimetry.One hundred twenty-six...
We describe a bidirectional color Doppler Fourier-domain optical coherence tomography system capable of measuring absolute velocities moving scatterers by illuminating the sample with two linearly and orthogonally polarized beams, incident at known angle on sample. The velocity calculation is independent exact orientation vector in detection plane. First measurements were performed rotating disk driven well-defined tilted various small angles. Our results indicate high correlation between...
Purpose.: To characterize total retinal blood flow in a group of healthy subjects. Methods.: Included this study were 64 volunteers. Retinal venous diameters measured using dynamic vessel analyzer. velocities bidirectional laser Doppler velocimetry. All vessels with diameter >60 μm entering the optic nerve head measured. Total was by summing up all data from individually vessels. In subgroup 10 subjects measurements also taken arterioles, and results obtained for as both venules arterioles...
Purpose.: The present experiments were undertaken to evaluate the validity of absolute flow velocity measurements with a dual-beam bidirectional Doppler Fourier-domain optical coherence tomography (FD-OCT) system. Methods.: velocities diluted milk through glass capillary measured at 30 different preset in range 0.9 39.3 mm/s by FD-OCT. was controlled two infusion pumps working ranges and based on technical principles. In vivo method for measuring blood retinal vessels tested bifurcations....
Purpose.: We compared the response of choroidal and optic nerve head blood flow (ChBF, ONHBF) in to an increase ocular perfusion pressure (OPP) during isometric exercise a decrease OPP artificial intraocular (IOP). Methods.: included 96 healthy subjects our study. In 48 was increased by 6 minutes squatting, either ONHBF (n = 24) or ChBF measured continuously. other continuously period IOP using suction cup. All measurements were done laser Doppler flowmetry. Results.: During all experiments...
Abstract. Purpose: Previous studies have reported an age‐dependent decline of macular pigment optical density (MPOD) as well a relative lack MPOD in age‐related degeneration (AMD). Results are, however, strongly dependent on the technique used. In this study, we investigated age dependence using spectral fundus reflectance. addition, hypothesized that patients with AMD reduced compared to healthy controls. Methods: A total 85 subjects and 96 were included study. The control showed wide range...
PURPOSE: To assess visual and refractive outcomes patient satisfaction after bilateral sequential implantation of a primary capsular bag intraocular lens (IOL) supplementary sulcus-fixated trifocal IOL. METHODS: All patients had mono-focal IOL in the followed by (Sulcoflex 703F, Rayner Intraocular Lenses Limited) sulcus. Patients were evaluated for monocular uncorrected corrected distance acuity, binocular distance, intermediate near photopic mesopic contrast sensitivity, defocus curves,...
A device that allows for the measurement of ocular fundus pulsations at preselected axial positions a subject's eye is presented. Unlike previously presented systems, which only allow observation strongest reflecting retinal layer, our system enables layer. For this purpose sample illuminated by light low temporal coherence. The layer then selected positioning one mirror Michelson interferometer according to depth contains length based on partial coherence interferometry and line scan...
The visual performance of monofocal, bifocal, and trifocal intraocular lenses was evaluated by human individuals using a vision simulator device. This allowed investigation the impression after cataract surgery, without need actually to implant lenses.The randomized, double-masked, three-way cross-over study conducted on 60 healthy male female subjects aged between 18 35 years. Visual acuity (Early Treatment Diabetic Retinopathy Study; ETDRS) contrast sensitivity tests (Pelli-Robson) under...
Low-coherence tissue interferometry is a technique for the depth-resolved measurement of ocular fundus pulsations. Whereas pulsation amplitudes at preselected axial positions can readily be assessed by this method, coupling interferometer with pulse oximeter additionally allows reconstruction time course respect to cardiac cycle subject. For purpose, interferogram resulting from superposition waves reflected cornea and recorded synchronously plethysmogram. A new method evaluating synthetic...
Optical levers for precision angle measurement have the advantage of exerting only a negligible force on object being measured. Also, in autocollimating configuration, optical are insensitive to longitudinal movements target mirror. In this article, reference-beam multi-slit autocollimator with variable number slits, built from cost-effective off-the-shelf components, is presented. Further, an optimized algorithm data processing introduced, reducing computational effort repeated Gaussian...
A bidirectional FDOCT system capable of measuring absolute velocities moving scatterers is described. In this setup the sample illuminated with two differently polarized beams. These probe beams impinging onto at a known angle. The velocity estimation independent exact direction vector in detection plane. Evaluation measurements were performed on rotating disc driven well defined and tilted by various small angles around to π/2. Our results indicate high correlation between pre-set estimated...
Background Lutein and zeaxanthin are carotenoids that selectively taken up into the macula of eye, where they may protect against development age-related macular degeneration (AMD). Past studies have reported an agedependent decline pigment optical density (MPOD) in patients with AMD. In present study we investigated age-dependence MPOD melatonin using spectral fundus reflectance. addition, hypothesized AMD a reduced as compared to healthy controls.