Stefan Sacu

ORCID: 0000-0002-4920-2231
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About
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Research Areas
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Glaucoma and retinal disorders
  • Retinal and Optic Conditions
  • Intraocular Surgery and Lenses
  • Retinal and Macular Surgery
  • Ophthalmology and Visual Impairment Studies
  • Corneal surgery and disorders
  • Optical Coherence Tomography Applications
  • Retinal Development and Disorders
  • Ocular Diseases and Behçet’s Syndrome
  • Vascular Malformations Diagnosis and Treatment
  • Ocular Infections and Treatments
  • Cerebrovascular and Carotid Artery Diseases
  • Ocular Oncology and Treatments
  • Acute Ischemic Stroke Management
  • Peripheral Artery Disease Management
  • Antioxidant Activity and Oxidative Stress
  • Renal and Vascular Pathologies
  • Ocular Surface and Contact Lens
  • Cerebral Venous Sinus Thrombosis
  • Cardiovascular Health and Disease Prevention
  • Photodynamic Therapy Research Studies
  • Coronary Interventions and Diagnostics
  • Traumatic Ocular and Foreign Body Injuries

Medical University of Vienna
2016-2025

Universitätsklinik für Augenheilkunde
2005-2023

Universitätszahnklinik Wien
2008-2021

University of Vienna
2002-2021

Vienna Challenge Chamber
2020

American Academy of Optometry
2010

Ophthalmology Clinic
2005-2010

Arbeitsgemeinschaft für Klinische Ernährung
2006-2009

Vienna General Hospital
2005-2009

Southern California Eye Institute
2009

Arshad M. Khanani Sunil Patel Giovanni Staurenghi Ramin Tadayoni Carl J. Danzig and 95 more David Eichenbaum Jason Hsu Charles C. Wykoff Jeffrey S. Heier David R. Lally Jordi Monés Jared S. Nielsen Veeral Sheth Peter K. Kaiser Julie Clark Liansheng Zhu Hersh Patel Justin Tang Dhaval Desai Glenn J. Jaffe Arturo Alezzandrini A Francone Joaquín Bafalluy Silvina Bainttein José D. Luna Mario Saravia Matko Vidosevich Carlos Zeolite Federico Furno Sola Andrew Chang Elisa E. Cornish Thanh N. Nguyen Oliver Findl Anton Haas Martina Kralinger Stefan Sacu Laurence Postelmans Michel Eid Farah Maurício Maia Márcio Bittar Nehemy Fareed Ali Michael H. Brent Michael Dollin John R. Gonder Amin Kherani Andrew Merkur Raman Tuli Monica Marie Lopera Francisco J. Rodríguez Mario Bradvica Jan Ernest Kuldar Kalijurand Kai Noor Yves Cohen Catherine Creuzot‐Garcher F. De Bats François Devin Catherine Français-Maury Laurent Kodjikian Jean François Korobelnik Y. Le Mer M. Quaranta El Maftouhi Sam Razavi Eric H. Souied Ramin Tadayoni Michel Weber Nicole Eter Nicolas Feltgen Salvatore Grisanti Peter Walter Raffael Liegl Katrin Lorenz Georg Spital Siegfried Priglinger Martin S. Spitzer Michael Völker Tim U. Krohne Claudia Jochmann Chris P. Lohmann Carsten Framme Ágnes Kerényi András Papp András Seres Edit Tóth‐Molnár Alexis Tsorbatzoglou A VAJAS Balázs Varsányi Gábor Vogt Asaf Bar Eva Eting David Hauser Jamie Levy Nurit Mathalone Haia Morori-Katz Irit Rosenblatt Shiri Soudry-Zayit Omert Trivizky Francesco Bandello Antonio P. Ciardella Michele Figus

10.1016/s0140-6736(23)01583-0 article EN The Lancet 2023-09-08

purpose. To demonstrate a new generation of three-dimensional (3-D) ultrahigh-resolution optical coherence tomography (UHR OCT) technology for visualization macular diseases. methods. One hundred forty eyes with distinct disease in each the posterior pole compartments were examined 3-D UHR OCT. imaging was performed high axial resolution 3 μm compact, commercially available, ultra–broad-bandwidth (160 nm) titanium:sapphire laser at video rate up to 25 B-scans/s. Each tomogram consisted 1024...

10.1167/iovs.05-0370 article EN Investigative Ophthalmology & Visual Science 2005-08-25

There is evidence from several large-scale clinical trials that reduced intake of lutein, a major component the macular pigment, risk factor for development AMD. In present study (LISA; Lutein Intervention Study Austria) it was hypothesized lutein supplementation increases pigment optical density (MPOD). addition, an investigation conducted into whether improves visual acuity (VA) and function (mean differential light threshold; MDLT), as assessed with microperimetry.One hundred twenty-six...

10.1167/iovs.11-7522 article EN Investigative Ophthalmology & Visual Science 2011-08-28

<h3>Aims</h3> To quantify the change in drusen volume over time and identify its prognostic value for individual risk assessment. <h3>Methods</h3> A prospective observational study a minimum of 3 years maximum 5 follow-up examination every months was conducted at ophthalmology department Medical University Vienna. 109 patients presenting early intermediate age-related macular degeneration (AMD) were included, which 30 concluded regular least years. 50 eyes imaged using spectral-domain...

10.1136/bjophthalmol-2016-308422 article EN cc-by-nc British Journal of Ophthalmology 2016-04-04

To compare the posterior capsule opacification (PCO) inhibiting effect of sharp optic edge design Sensar OptiEdge AR40e intraocular lens (IOL) (Allergan Surgical) with that round-edged AR40 IOL. Setting Department Ophthalmology, University Vienna, Austria.This prospective randomized patient- and examiner-masked study comprised 106 eyes 53 patients bilateral age-related cataract. Each patient had cataract surgery in both received an IOL 1 eye other eye. Postoperative examinations were at...

10.1016/s0886-3350(02)01371-8 article EN Journal of Cataract & Refractive Surgery 2002-07-01

To compare measurements performed with the IOLMaster (Carl Zeiss, Meditec AG) those obtained by applanation ultrasound (US) and manual keratometry to evaluate effect of operator experience on US biometry.Department Ophthalmology, University Vienna, Austria.The axial length (696 eyes) anterior chamber depth (ACD) (462 were measured in 377 patients cataract using US. assess biometric results, operators divided into 2 groups: experienced less performing biometry. The difference between methods...

10.1016/s0886-3350(03)00243-8 article EN Journal of Cataract & Refractive Surgery 2003-10-01

To suggest a novel classification of neovascular age-related macular degeneration (AMD) based on optical coherence tomography angiography (OCTA) and to correlate morphological characteristics (OCT)/OCTA with clinical criteria disease activity.A total 88 eyes AMD (14 treatment-naïve, 74 following anti-vascular endothelial growth factor treatment (VEGF)) were examined using the AngioVue OCTA system (Optovue, Inc., Fremont, CA, USA) evaluated vascular morphology. Choroidal neovascularization...

10.1111/aos.13364 article EN Acta Ophthalmologica 2017-01-30

Purpose: To investigate the course of inflammatory and angiogenic cytokines in aqueous humor patients with persistent/recurrent neovascular age-related macular degeneration (nAMD) under ranibizumab monotherapy (IVM) or plus dexamethasone combination treatment. Methods: In this 12-month prospective study, 40 eyes nAMD were treated either IVM combined treatment intravitreal implant (IVC). Patients group following an "as needed" regimen; IVC received a at baseline re-treated ranibizumab. At...

10.1167/iovs.16-19772 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2016-08-15

PurposeTo correlate the area of geographic atrophy (GA) and residual foveal sparing (FS), to identify minimum FS maximum GA allowing sufficient visual acuity (VA) for daily tasks.DesignProspective cohort study.MethodsThirty-six eyes 25 patients with were followed 18 months using spectral-domain optical coherence tomography VA tests. Volume scans imported into software enabling grading areas in B-scans computing planimetric measurements complete volume scans. Correlation 1 (complete atrophy),...

10.1016/j.ajo.2017.03.031 article EN cc-by-nc-nd American Journal of Ophthalmology 2017-04-04

Purpose: To investigate the impact of subretinal drusenoid deposits (SDD) and photoreceptor integrity on global local geographic atrophy (GA) progression. Methods: Eighty-three eyes 49 patients, aged 50 years older with GA secondary to age-related macular degeneration (AMD), were prospectively included in this study. Participants underwent spectral-domain optical coherence tomography (SD-OCT) fundus autofluorescence (FAF) imaging at baseline after 12 months. The junctional zone presence SDD...

10.1167/iovs.61.6.11 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2020-06-05

Purpose: To refine estimates of macular soft drusen abundance in eyes with age-related degeneration (AMD) and evaluate hypotheses about biogenesis, we investigated topographic distribution growth rates by optical coherence tomography (OCT). We compared results to retinal features similar topographies (cone density pigment) healthy eyes. Methods: In a prospective study, AMD were identified human observers OCT volumes analyzed computer-assistance. Published histologic data for cone densities...

10.1167/iovs.62.2.26 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2021-02-19

To compare the posterior capsule opacification (PCO) inhibiting effect of sharp optic edge design Sensar OptiEdge AR40e intraocular lens (IOL) with that double-round AR40 IOL over a period 3 years.Department Ophthalmology, Medical University Vienna, Austria.Fifty-three patients bilateral age-related cataract (106 eyes) were included in this randomized prospective patient- and examiner-masked clinical trial intraindividual comparison. Each study patient had surgery both eyes received...

10.1016/j.jcrs.2004.09.053 article EN Journal of Cataract & Refractive Surgery 2005-05-01

To investigate whether intravitreal ranibizumab (0.05 mL) treatment affects retinal vessel diameters and retrobulbar blood velocities in patients with acute branch vein occlusion (BRVO).Thirty clinically significant macular edema secondary to BRVO were included. The duration of the study was three months. Patients studied before one week, month, two months, months after first injection. Depending on clinical requirements, up injections administered. Retinal measured using a analyzer. Flow...

10.1167/iovs.10-5842 article EN Investigative Ophthalmology & Visual Science 2010-11-04

<h3>Aims:</h3> To evaluate the reliability of different optical coherence tomography (OCT) devices and scanning patterns in assessment retinal thickness segmentation performance neovascular age-related macular degeneration (nAMD). <h3>Methods:</h3> 28 eyes with nAMD 10 healthy were imaged using conventional time domain (TD) OCT as well three spectral-domain (SD) systems. Radial scans 6 mm size compared between Stratus Topcon OCT, addition to raster all SD-OCT devices. Retinal values...

10.1136/bjo.2008.153643 article EN British Journal of Ophthalmology 2009-06-10

PURPOSE: To compare posterior capsule opacification (PCO) and neodymium:YAG (Nd:YAG) laser capsulotomy rates 10 years after surgery between two 3-piece intraocular lenses (IOLs): a silicone IOL with round optic edges hydrophobic acrylic sharp edges. SETTING: Department of Ophthalmology, Medical University Vienna, Vienna General Hospital, Austria. METHODS: Patients having had cataract implantation at least 1 study by the same surgeon 1994 1999 were retrospectively examined. The number Nd:YAG...

10.1016/j.jcrs.2008.11.044 article EN Journal of Cataract & Refractive Surgery 2009-02-28

To investigate the influence of intravitreal dexamethasone implant on inflammatory and angiogenic cytokine levels in aqueous patients with retinal vein occlusion (RVO).Forty eyes 40 consecutive macular oedema (ME) due to branch central (BRVO/CRVO) were treated an (Ozurdex® ) at baseline evaluated until month 6. Retreatment was performed case recurrent ME earliest 4 months after treatment. Aqueous humour samples taken baseline, 1, 3, 6 time each retreatment. Concentrations 29 different...

10.1111/aos.13152 article EN Acta Ophthalmologica 2016-07-15

Purpose: The purpose of this study is to compare the ability spectral domain optical coherence tomography angiography (SD-OCTA) and indocyanine green (ICGA) detect measure lesion area in patients with type 1 2 choroidal neovascularization (CNV). Methods: Types neovascular AMD (nAMD) were included prospective observational case series. ETDRS best-corrected visual acuity (BCVA), ophthalmic examination funduscopy, OCTA (AngioVue), fluorescein (FA), ICGA, OCT (Spectralis) performed. CNV...

10.1167/iovs.17-22902 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2018-05-07
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