Abstract Background To evaluate the frequency and anterior segment optical coherence tomography parameters of patients with scleral fixated intraocular lenses (IOL) reverse pupillary block (RPB). Methods Retrospective analysis at a tertiary care centre (Department for Ophthalmology Optometry, Medical University Vienna, Austria). We researched our records who underwent IOL implantation from January 2018 till February 2023. Patients were included only if there was least one adequate...

Purpose: To investigate the impact of subretinal drusenoid deposits (SDD) and photoreceptor integrity on global local geographic atrophy (GA) progression. Methods: Eighty-three eyes 49 patients, aged 50 years older with GA secondary to age-related macular degeneration (AMD), were prospectively included in this study. Participants underwent spectral-domain optical coherence tomography (SD-OCT) fundus autofluorescence (FAF) imaging at baseline after 12 months. The junctional zone presence SDD...

Abstract The presence of corneal vascularization (CV) interferes with the angiogenic and immune privilege cornea, risking rejection in eyes following keratoplasty. Pre-operative (lymph)-angioregression is a promising therapeutic approach, but objective monitoring by non-invasive CV imaging needed. purpose this study was to investigate anterior-segment optical coherence tomography angiography (AS-OCTA) for visualization quantification, show its superiority over slit-lamp photography high-risk...

To evaluate the refractive prediction error of common intraocular lens (IOL) power calculation formulae in patients who underwent intrascleral IOL fixation using two different techniques.This is a prospective, randomized, longitudinal, single-site, single-surgeon study. Patients implantation Yamane or Carlevale technique were followed up for period six months postoperatively. Refraction was measured best-corrected visual acuity at 4 m (EDTRS chart). Lens decentration, tilt and effective...

Abstract Purpose To investigate the long‐term effects and dynamic changes in scleral thickness above T‐haptic after sutureless scleral‐fixated intraocular lens (sSFIOL) implantation using FIL‐SFF Carlevale lens. Setting Single‐centre, single‐surgeon, prospective clinical trial, Department of Ophthalmology, Medical University Vienna, Austria. Methods Thirty‐six eyes 36 consecutive patients met inclusion criteria for this post hoc analysis. Visual acuity, tilt decentration IOL, as well...

The life-cycle of a World Wide Web service includes analysis, design, implementation and maintenance stages. Our experiences in building maintaining the annual Vienna International Festival's site have led us to create engineering tools that cover all these phases.

Subretinal fibrosis is one of the most prevalent causes blindness in elderly population, but a true gold standard to objectively diagnose still lacking. Since fibrotic tissue birefringent, it can be detected by polarization-sensitive optical coherence tomography (PS-OCT). We present new algorithm automatically detect, segment, and quantify lesions within 3D data sets recorded PS-OCT. The first compensates for birefringence anterior ocular tissues then uses uniformity birefringent optic axis...

Abstract To find baseline predictors for subretinal fibrosis (SF) in neovascular age-related macular degeneration (nAMD). Forty-five eyes of 45 participants with treatment-naïve nAMD were consecutively enrolled and treated according to a standardized treat-and-extend protocol. Spectral-domain optical coherence tomography (OCT), color fundus photography fluorescein angiography as well novel imaging modalities polarization-sensitive OCT (OCTA) performed detect SF after 1 year development....

Purpose: To assess retinal function in areas of presumed fibrosis due to neovascular age-related macular degeneration (nAMD), using multimodal imaging and structure-function correlation. Design: Cross-sectional observational study. Methods: 30 eyes consecutive patients with nAMD a minimum history one year anti-vascular endothelial growth factor therapy were included. Each patient underwent microperimetry (MP), color fundus photography (CFP), standard spectral-domain-based OCT (SD-OCT),...

Previous studies have identified a link between optical coherence tomography (OCT)-derived and OCT angiography (OCTA)-based parameters in patients with neovascular AMD (nAMD); the latter may serve as direct biomarkers for macular neovascularization (MNV) activity. The aim of this study was to assess individual influence retinal thickness (RT) well intra- sub-retinal fluid (IRF, SRF) presence on treatment response over time assessed by previously OCTA-derived MNV vascular parameters.During...

To compare intraindividual differences in visual performance of a monofocal and enhanced intraocular lens (IOL) the same platform.

Abstract Purpose To identify the changes in distinct vascular parameters of choroidal neovascularization (CNV) eyes with treatment‐naïve neovascular age‐related macular degeneration (nAMD) during primary response to anti‐VEGF therapy using aflibercept. Methods Patients were prospectively followed first 3 months according a standardized protocol mandatory visits at days 7 and 14 after each treatment up day 90. Fourteen seen addition 1 post‐initial injection. Aflibercept was administered...

Abstract Purpose To identify correlations between the vascular characteristics of macular neovascularization (MNV) obtained by optical coherence tomography angiography (OCTA) and distinct retinal fluid volumes in neovascular age‐related degeneration (nAMD). Methods In this prospective interventional study, 54 patients with treatment‐naïve type 1 or 2 nAMD were included treated intravitreal aflibercept. At baseline month 1, each patient underwent a SD‐OCT volume scan volumetric flow using...

Purpose To evaluate the differences in incidence of posterior capsule opacification (PCO) and visual optical performance between 2 hydrophobic acrylic single-piece sharp-edged intraocular lenses (IOLs) over 3 years. Setting Department Ophthalmology, Medical University Vienna, Austria. Design Prospective randomized case series. Methods Patients with bilateral cataract were prospectively to receive an Eyecee One IOL (IOL A) or Acrysof SN60WF B) followed for 36 months. The corrected distance...

To prospectively investigate the development of quantitative autofluorescence (qAF) during progression from intermediate to late age-related macular degeneration (AMD).Quantitative images patients with AMD were acquired every three months a Spectralis HRA + OCT (Heidelberg Engineering, Heidelberg, Germany) using built-in reference. The association between changes in longitudinal qAF and toward was assessed Cox regression models time-dependent covariates.One hundred twenty-one eyes 71...

Abstract Purpose To assess rotational stability and refractive outcomes of a new toric hydrophobic acrylic intraocular lens (IOL). Design Single-center, prospective, interventional clinical trial. Methods A total 130 eyes 82 patients with age-related cataract corneal astigmatism greater than 1.0 diopters (D) received IOL Clareon CNW0T3-9. Baseline measurement for evaluation was performed at the end surgery (EOS), patient still supine on operating table, using non-movable vessels as reference...

To investigate quantitative associations between AI-assessed disease activity and optical coherence tomography angiography (OCTA)-derived parameters in patients with neovascular age-related macular degeneration (nAMD) undergoing anti-VEGF therapy. OCTA SD-OCT images obtained from multicenter, randomized study data were evaluated. A deep learning algorithm (RetInSight) was used to detect quantify fluid on SD-OCT. Mixed effects models applied evaluate correlations volumes, neovascularization...

Optical coherence tomography (OCT) is the most widely used imaging modality in ophthalmology. There are multiple variations of OCT capable producing complementary information. Thus, registering these volumes desirable order to combine their In this work, we propose a novel automated pipeline register images produced by different devices. This based on two steps: multi-modal 2D en-face registration deep learning, and Z-axis (axial axis) retinal layer segmentation. We evaluate our method using...

Purpose: The aim of this study was to investigate whether structural OCT changes, in specific retinal thickness, is associated with the vascular response within nAMD CNV lesion. In other words, SSOCTA derived parameters may prove suitable assess activity future.Methods: During first 3 months patients were prospectively followed visits at days 7, and 14 after each anti-VEGF treatment up day 90. At baseline, 30 60 Aflibercept administered. OCT-derrived thickness (RT) OCTA-derived lesion...

Purpose To assess the signal composition of cone photoreceptors three-dimensionally in healthy retinas using adaptive optics optical coherence tomography (AO-OCT). Methods Study population. Twenty eyes ten subjects (age 23 to 67). Procedures. After routine ophthalmological assessments, were examined AO-OCT. Three-dimensional volumes acquired at 2.5° and 6.5° foveal eccentricity four main meridians (superior, nasal, inferior, temporal). Cone densities compositions investigated different...

Purpose: To evaluate morphologic and microvascular differences between eyes with without subretinal fibrosis (SF) caused by neovascular age-related macular degeneration (nAMD). Methods: Patients nAMD a minimum history of 12 months anti-VEGF treatment were prospectively included in this cross-sectional study. imaged using standard imaging, swept-source optical coherence tomography angiography for quantitative analysis polarization-sensitive OCT as an ancillary method automated SF...

Complex Web services are comparable to large software systems thus their management and engineering process requires feasible sophisticated methodologies processes. Standard page editors site tools not built for architecting complex cannot handle all tasks in the service process. We introduced JESSICA system utilize object-oriented concepts management. To support stages of a service's life cycle, from architectural design via object-based model definition implementation maintenance documents...

To be successful, e-commerce and Web information systems depend on systematic analysis design processes. Even more important, our method is based standard techniques like UML, XML, Corba. It also allows for the integration of different kinds clients from Java over HTML to WAP into a distributed environment. Through smooth highly heterogeneous legacy software databases, object oriented provides achieve this goal.

An adaptive optics optical coherence tomography (AO-OCT) system is used to assess sixty healthy eyes of thirty subjects (age 22 75) evaluate how the outer retinal layers, foveal eccentricity and age effect mean cone density. The mosaics different planes (the inner segment junction (IS/OS), combined with IS/OS (ISOS+), tips (COST), full en-face plane (FEF)) at four main meridians (superior, nasal, inferior, temporal) para- perifoveal eccentricities (ecc 2.5° 6.5°) were analyzed...