A5006458752- Lung Cancer Treatments and Mutations
- Respiratory Support and Mechanisms
- Lung Cancer Research Studies
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer Immunotherapy and Biomarkers
- Sepsis Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Occupational and environmental lung diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Ultrasound in Clinical Applications
- COVID-19 Clinical Research Studies
- Quinazolinone synthesis and applications
- Pneumonia and Respiratory Infections
- Intensive Care Unit Cognitive Disorders
Kyoto University
2024
Saiseikai Kumamoto Hospital
2017-2024
Scientific Research WorkS Peer Support Group
2024
Santen (Japan)
2024
Kyoto Min-iren Asukai Hospital
2024
Rationale: Chest computed tomography is performed in patients with empyema for various reasons. However, its predictive ability patient outcomes has not been evaluated. Objectives: To evaluate the of findings (pleural thickness, loculation, interlobar pleural effusion, lung abscess, and bronchopleural fistula) 90-day mortality empyema. Methods: This multicenter retrospective cohort study was conducted across six acute care hospitals Japan. We included confirmed diagnoses who underwent chest...
Abstract Background The use of baseline tumor burden (TB) as a prognostic factor for non‐small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICIs) and associations between TB other biomarkers remain unclear. In this study, we investigated the association survival in NSCLC ICIs comparison biomarkers. Methods We retrospectively evaluated 83 administered February 2016 December 2018. was measured sum unidimensional diameters up to five target lesions. Results...
We aimed to develop algorithms identify patients with acute exacerbation of interstitial pneumonia and lung diseases using Japanese administrative data.
Alectinib, a second-generation anaplastic lymphoma kinase (ALK) inhibitor, is key drug for ALK rearranged lung adenocarcinoma. Interstitial disease (ILD) an important adverse effect of alectinib, which generally requires termination treatment. However, we treated two patients with drug-induced ILD who continued to receive alectinib. Patient 1 was 57-year-old male ALK-rearranged Stage IV adenocarcinoma administered alectinib as first-line therapy. Computed tomography (CT) detected...
Abstract Background Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR‐TKIs) are used to treat patients with non‐small cell lung cancer (NSCLC) and EGFR driver mutations. Although some discontinued these treatments because of adverse events, it is unclear whether switching EGFR‐TKI events provides a benefit. Methods This retrospective study evaluated data from 22 mutation‐positive NSCLC who received at least two EGFR‐TKIs that were switched (March 2011 September 2017)....
Because of limitations in previous randomised controlled trials and observational studies, the effectiveness immediate video-assisted thoracoscopic surgery (VATS) for patients with empyema real-world settings remains unclear.This study aimed to evaluate whether VATS improves clinical outcomes empyema.This multicentre retrospective cohort included 744 physician-diagnosed from six hospitals between 2006 2021. The exposure was performed within 3 days diagnosis, primary outcome 30-day mortality,...
There have been no report of objective clinical characteristics or prognostic factors that predict fatal outcome acute respiratory distress syndrome (ARDS) since the Berlin definition was published. The aim this study is to identify clinically available predictors distinguish between two phenotypes ARDS due pneumonia. In total, 104 cases Japanese patients with pneumonia-induced were extracted from our prospectively collected database. Fatal divided into early (< 7 days after diagnosis) and...
Background: Video-assisted thoracoscopic surgery is a widely recommended treatment for empyema in advanced stages. However, only few studies have evaluated prognostic factors among patients with who underwent video-assisted surgery. Furthermore, no predictors of direct discharge home.
Abstract Background: The COVID-19 pandemic has renewed interest and discussion about clinical phenotypes of acute respiratory distress syndrome (ARDS). Since the Berlin definition, various disease courses with fatal outcome have been described but early objective indicators predicting distinct remained elusive. Objectives: Identify clinically available predictors that distinguish between two ARDS due to pneumonia.Methods: 104 Japanese patients pneumonia induced were extracted from our...