A5050297211- Respiratory Support and Mechanisms
- Ultrasound in Clinical Applications
- COVID-19 Clinical Research Studies
- Statistical Methods in Clinical Trials
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Airway Management and Intubation Techniques
- Phonocardiography and Auscultation Techniques
- COVID-19 and healthcare impacts
- Tracheal and airway disorders
- Sepsis Diagnosis and Treatment
- Meta-analysis and systematic reviews
- COVID-19 Impact on Reproduction
- Malaria Research and Control
- Acute Ischemic Stroke Management
- Thermoregulation and physiological responses
- IoT-based Smart Home Systems
- Cardiac Arrest and Resuscitation
- Antibiotic Use and Resistance
- COVID-19 diagnosis using AI
- Cardiac, Anesthesia and Surgical Outcomes
- Bacterial Infections and Vaccines
- Thermal Regulation in Medicine
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Health and Mental Health
- Acute Myocardial Infarction Research
Narayana Health
2020-2024
Mazumdar Shaw Medical Centre
2020-2023
Jawaharlal Nehru Medical College
2022
Abstract Background Optimal anti-bacterial activity of meropenem requires maintenance its plasma concentration (Cp) above the minimum inhibitory (MIC) pathogen for at least 40% dosing interval (fT > MIC 40). We aimed to determine whether a 3-h extended infusion (EI) achieves fT 40 on first and third days therapy in patients with severe sepsis or septic shock. also simulated performance EI respect other pharmacokinetic (PK) targets such as 4 × 40, = 100, 100. Methods Arterial blood samples...
Coronavirus disease-2019 (COVID-19) causes various cardiopulmonary manifestations. Bedside ultrasound helps in the rapid diagnosis of these Vscan Extend™ (GE, Wauwatosa, WI, USA) is a handheld device with dual probe and an artificial intelligence application to detect ejection fraction. It can help reducing time for diagnosis, duration, number healthcare workers exposed COVID-19. This prospective observational study comparing cardiorespiratory parameters duration assessment between...
Every patient in neurocritical care evolves through two phases. Acute pathologies are addressed first. These include trauma, hemorrhagic or ischemic stroke, neuroinfection. Soon after, the concentration shifts to identifying secondary like fever, seizures, and ischemia, which may exacerbate brain injury. Frequent bedside examinations not sufficient for timely detection prevention of injury (SBI) as per International Multidisciplinary Consensus Conference on Multimodality Monitoring...
The probability value (p-value) is used in hypothesis testing to assist determining if the null should be rejected. In a practical setting, p-value helps determine an experiment conducted and then compares outcomes what random chance may yield. order do it, researchers state “null hypothesis” that they want disapprove. Many consider essential summary of statistical analysis their research data. Although it undeniable p-values are very useful method for summarizing study results, also...
Mycobacterium abscessus is a very unusual cause of infection in immunocompetent patients. It rapidly growing microbe that rarely causes disseminated or native valve endocarditis. This organism exhibits intrinsic and acquired resistance to multiple antibiotics hence becomes major issue planning treatment regimens. We report unique case young male patient presenting with stroke persistent fever. After extensive investigations, he was found have an abscess caused by M. the sinus Valsalva...
Pyogenic ventriculitis is defined as the inflammation of ependymal lining cerebral ventricular system. It characterized by presence suppurative fluid in ventricles. mostly affects neonates and children but rarely can be seen adult population. In adults, it usually elderly healthcare associated occurs secondary to ventriculoperitoneal shunt, external drain, intrathecal drug delivery, brain stimulation devices, neurosurgical intervention. Primary pyogenic though rare should considered one...
Background: Sepsis-related deaths contribute up to 20% of all global deaths, with the highest-burden from sub-Saharan Africa and Southeast Asia. Cytokines are mediators organ dysfunction in systemic inflammatory response syndrome (SIRS) across varied aetiologies, including sepsis. The imbalance pro anti-inflammatory cytokines continues be crux pathophysiology septic shock. Therapies treat either by antagonizing them or filtering out body evolving. Hemoadsorption is a process other...
Malaria is a worldwide health concern, but great majority of cases occur in tropical countries like India. With almost 95% Indian population living malaria endemic regions, India contributes to most the global and deaths, outside African countries. Despite significant advances towards control eradication, mortality associated with severe remains particularly high. Changing epidemiology, vulnerable patient population, overlapping symptomatology, limited availability parenteral preparations...
simple forgetfulness or possibly, cultural beliefs that these devices are unsafe, addictive, difficult to use. [16] conclusion, an in-depth knowledge should be provided the asthma patients in relation their severity of illness, nature medications, comorbidities, and troubleshooting during exacerbations, explained them own language encourage self-care improve long-term outcomes.
A recent global pandemic has resulted from the outbreak of coronavirus disease (COVID-19) infection. One key clinical features this infection is presence severe acute respiratory syndrome 2 virus. The port entry for COVID-19 lung and if worsens, it progresses to distress (ARDS). As continue surge, findings studies case reports suggest that ARDS caused by might have different characteristics than what we refer as non-COVID-19 (Typical) ARDS. By applying differences in between COVID-19-related...
Critical Appraisal of RCTsMany articles have discussed the method assessing validity a trial, 1,6,7 purpose this article is to highlight factors related interpretation clinical studies and trials.Randomized controlled trials (RCTs) are prospective CTs where study participants randomized one groups or cohorts.These done evaluate safety efficacy new drugs, interventions, diagnostic tests. 8
Precision medicine also known as "personalized medicine" is a healthcare delivery system based on identifying biomarkers using genomics to link endotypes with phenotypes.Significant overlap exists between different phenotypes.Endotyping helps in giving more precise definition of the phenotypes.However, it has proved be most helpful development therapeutics oncology.Precision been brought much common use COVID-19 various drugs developed targeting interleukins.Precision now being actively for...
Cytokines are a varied group of proteins released by our immune system and play an essential role in normal responses.There different cytokines, including chemokines, interferons, interleukins (IL), lymphokines, tumor necrosis factor (TNF).The primary functions cytokines include inflammatory response, angiogenesis, down upregulation receptors, control cell differentiation. 5owever, response to severe reaction, many into the bloodstream.This sudden increase is known as cytokine storm. 5It can...