A5054363920- Nonlinear Dynamics and Pattern Formation
- Neural dynamics and brain function
- Cardiac electrophysiology and arrhythmias
- stochastic dynamics and bifurcation
- Neural Networks and Applications
- Cellular Automata and Applications
- ECG Monitoring and Analysis
- Advanced Data Processing Techniques
- Force Microscopy Techniques and Applications
- Obstructive Sleep Apnea Research
- Asthma and respiratory diseases
- Photoreceptor and optogenetics research
- Theoretical and Computational Physics
- Opinion Dynamics and Social Influence
- Cardiovascular and Diving-Related Complications
Hospital Universitari Arnau de Vilanova
2025
Biomedical Research Institute of Lleida
2025
Instituto de Salud Carlos III
2025
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2025
KU Leuven
2021-2024
University College West Flanders
2021-2023
The use of continuous positive airway pressure prevents an increase in blood normotensive subjects with a dipping pattern and severe obstructive sleep apnoea. Background : effects (CPAP) on (BP) subjects, particularly among those BP pattern, remain uncertain, raising questions about its indication for this group patients. We assessed the impact CPAP apnoea (OSA). Methods Randomised, parallel, prospective, controlled trial. Inclusion criteria were apnoea-hypopnea index ≥30 events/hour, mean...
Several excitable systems, such as the heart, self-organize into complex spatio-temporal patterns that involve wave collisions, breaks, and rotating vortices, of which dynamics are incompletely understood. Recently, conduction block lines in two-dimensional media were recognized phase defects, on quasi-particles can be defined. These particles also form bound states, one corresponds to classical singularity. Here, we relate structure dynamical attractor state space extend framework three...
During cardiac arrhythmias, dynamical patterns of electrical activation form and evolve, which are interest to understand cure heart rhythm disorders. The analysis these is commonly performed by calculating the local phase searching for singularities (PSs), i.e., points around all phases present. Here we propose an alternative framework, focuses on defect lines (PDLs) surfaces (PDSs) as more general mechanisms, include PSs a specific case. proposed framework enables two conceptual...
Excitable media are ubiquitous in nature, and such systems the local excitation tends to self-organize traveling waves, or rotating spiral-shaped patterns two three spatial dimensions. Examples include waves during a pandemic electrical scroll heart. Here we show that phenomena can be extended space of four more dimensions propose connections excitable elements network setting regarded as additional Numerical simulations performed using FitzHugh-Nagumo model, showing vortices rotate around...
Electrical waves that rotate in the heart organize dangerous cardiac arrhythmias. Finding region around which such rotation occurs is one of most important practical questions for arrhythmia management. For many years, main method finding regions was so-called phase mapping, a continuous assigned to points based on their excitation status and defining as point singularity. Recent analysis, however, showed regimes there exist discontinuities must be defined not singularity, but defect line....
Abstract Many extended chemical and biological systems self-organise into complex patterns that drive the medium behaviour in a non-linear fashion. An important class of such are excitable media, including neural cardiac tissues. In wave breaks can form rotating turbulence. However, onset, sustaining elimination is currently incompletely understood. The classical theory phase singularities media was recently challenged, as lines conduction block were identified discontinuities. Here, we...
Excitable media are ubiquitous in nature, and such systems the local excitation tends to self-organize traveling waves, or rotating spiral-shaped patterns two three spatial dimensions. Examples include waves during a pandemic electrical scroll heart. Here we show that phenomena can be extended space of four more dimensions propose connections excitable elements network setting regarded as additional Numerical simulations performed using FitzHugh-Nagumo model, showing vortices rotate around...
The contraction of the heart muscle is triggered by self-organizing electrical patterns. Abnormalities in these patterns lead to cardiac arrhythmias, a prominent cause mortality worldwide. targeted treatment or prevention arrhythmias requires thorough understanding interacting wavelets, vortices and conduction block sites within excitation pattern. Currently, there no conceptual framework that covers elementary processes during arrhythmogenesis detail, particular transient pivoting observed...
Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main source(s): KU Leuven and FWO-Flanders Introduction To study the excitation patterns spiral waves in two spatial dimensions over time, it is useful to abstract them much simpler mathematical structures. Previously, those have been abstracted phase singularities: single points around which moves [1,2]. Recently, was proposed upgrade these defect lines [3,4]. The dynamics either structures...
Abstract Electrical waves that rotate in the heart organize dangerous cardiac arrhythmias. Finding region around which such rotation occurs is one of most important practical questions for arrhythmia management. For many years, main method finding regions was so-called phase mapping, a continuous assigned to points based on their excitation status and defining as point singularity. Recent analysis, however, showed regimes there exist discontinuities must be defined not singularity, but...
During cardiac arrhythmias, dynamical patterns of electrical activation form and evolve, which are interest to understand cure heart rhythm disorders. The analysis these is commonly performed by calculating the local phase searching for singularities (PSs), i.e. points around all phases present. Here we propose an alternative framework, focuses on defect lines (PDLs) surfaces (PDSs) as more general mechanisms, include PSs a specific case. proposed framework enables two conceptual...