This study aims to determine the mediating effects of psychological empowerment on abusive supervision and turnover intention as perceived by nurses provide information change status nurse turnover.A cross-sectional survey (a questionnaire examining perceptions supervision, measurement empowerment, for intention) was used collect data. A total 1127 clinical nurses, who were recruited through convenience sampling, participated in survey.Nurses' average scores 1.62 ± 0.95, 3.24 0.83, 14.17...

Abstract MicroRNA‐143‐3p (miR‐143‐3p) is involved in the initiation of inflammatory response and progression cardiovascular diseases. Myocardial hypertrophy a common symptom numerous In current study, we attempted to demonstrate role miR‐143‐3p development myocardial by focusing on its association with inflammation. was induced transverse aortic constriction (TAC) method vivo H 2 O administration vitro. The expression status downstream effectors were detected animal heart tissues H9c2 cells....

Myocardial infarction (MI) is an unsolved health problem which seriously affects human around the world. miR-34a-5p acting as a tumor-suppressor associated with left ventricular remodeling. We aimed to explore functional roles of in cardiomyocytes. Hypoxia-induced cell injury H9c2, HL-1 and cardiac myocytes was analyzed according decrease viability increase apoptosis. Expression measured by quantitative reverse transcription polymerase chain reaction (qRT-PCR) when concentration O2...

Colorectal cancer (CRC) remains one of the most common cancers worldwide. HS1-associated protein X-1 (HAX-1) has been highlighted as an important marker in many types cancers. However, little is known about role HAX-1 CRC. The aim this study was to analyze correlation expression with clinicopathological features and mRNA levels were examined by immunohistochemistry (IHC) real-time quantitative reverse-transcriptase polymerase chain reaction (RT-qPCR) CRC tissues adjacent noncancerous...

Abstract Myocardial ischemia is accompanied with hypoxia injury in myocardial cells. Long noncoding RNAs (lncRNA) CAMK2D‐associated transcript 1 (C2dat1) C2dat1) has been linked several ischemic diseases. However, the investigation regarding its role relatively rare. The aim of this study was to examine C2dat1 response H9c2 cells were subjected evoke cell damage. Expressions C2dat1, miR‐22, and VEGF altered by transfection, then survival, migration, invasion respectively assessed...

Histopathological image contains rich phenotypic information, which is beneficial to classifying tumor subtypes and predicting the development of diseases. The vast size pathological slides makes it impossible directly train whole slide images (WSI) on convolutional neural networks (CNNs). Most previous weakly supervision works divide high-resolution WSIs into small patches separately input them CNN classify as tumors or normal areas. first difficulty that although method based framework...

Abstract Background Longitudinal stent deformation (LSD) is an infrequent complication of percutaneous coronary intervention (PCI), and it may lead to catastrophic clinical outcomes. However, reports cardiac adverse events associated with LSD are rare. Case presentation A 55-year-old man chest pain was treated for a severe left anterior descending branch (LAD)-diagonal 1 (D1) bifurcation lesion by PCI two stents in the proximal LAD. occurred during withdrawal trapped D1 wire. High-pressure...

The aim of this study was to investigate the expression CD44 and its clinical significance in children suffering from hepatoblastoma (HB).CD44 detected with immunohistochemistry staining 30 samples 10 normal liver tissue children.The data obtained statistically analyzed using chi-square test, SPSS (v.11.0) software.The rate significantly higher (66.7%) tissues than (χ 2 = 4.848, P < 0.05).The stage III or IV (83.3%) that I II ＝ 5.625, 0.05) (41.7%).Therefore, might play an important role...

By combining the expression profiles of metabolism-related genes (MRGS) with clinical information, quantities MRGS and influence on development prognosis were systematically analyzed, so as to provide a theoretical basis for study Ewing's sarcoma. MRGs 64 patients sarcoma obtained from GEO dataset. Univariate Cox regression analysis was used identify metabolization-related differentially expressed (DEGs) related in patients. Then, multivariate calculate novel prognostic markers based DEGs....

The aim of this study was to compare and analyze the tensile mechanical properties ascending aorta (AA) in Wistar Kyoto (WKY) rats spontaneously hypertensive (SHRs), for purpose providing a biomechanical basis hypertension prevention.Pulse wave velocities (PWV) serum nitric oxide (NO) concentrations were determined 6-month-old WKY SHRs (n = 21, n respectively). Then, 20 AAs from each group obtained longitudinal testing.The maximum stress, strain, strain at stress 16 Kpa greater than (p <...

Cytological smears play an important role in disease diagnosis, particularly for specific cancers such as thyroid and cervical cancer, where cytological are primarily cell smears. With the rapid development of deep learning technology, more people using neural networks to classify discriminate cancers. However, getting ethically certified clear is hard, so training always based on small data sets. When facing with different levels brightness clarity, which collected from various devices...

Abstract Objective: By combining the expression profiles of metabolism-related genes (MRGS) with clinical information, quantities MRGS and influence on development prognosis were systematically analyzed, so as to provide a theoretical basis for study Ewing's sarcoma.Methods: MRGs 64 patients sarcoma obtained from GEO dataset. Univariate Cox regression analysis was used identify metabolization-related differentially expressed (DEGs) related in patients. Then, multivariate calculate novel...