Yongkang Zhang

ORCID: 0000-0001-9411-9704
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About
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Research Areas
  • Surface Treatment and Residual Stress
  • Laser Material Processing Techniques
  • Erosion and Abrasive Machining
  • Welding Techniques and Residual Stresses
  • High-Velocity Impact and Material Behavior
  • Electron Spin Resonance Studies
  • Metal Alloys Wear and Properties
  • Additive Manufacturing Materials and Processes
  • Aluminum Alloy Microstructure Properties
  • Tribology and Lubrication Engineering
  • Machine Fault Diagnosis Techniques
  • Diamond and Carbon-based Materials Research
  • Metal and Thin Film Mechanics
  • Advanced materials and composites
  • Hydrogen embrittlement and corrosion behaviors in metals
  • Gear and Bearing Dynamics Analysis
  • Mechanical Behavior of Composites
  • Lanthanide and Transition Metal Complexes
  • Engineering Diagnostics and Reliability
  • Corrosion Behavior and Inhibition
  • Cancer Research and Treatments
  • Laser and Thermal Forming Techniques
  • Advanced Welding Techniques Analysis
  • Advanced machining processes and optimization
  • Analytical Chemistry and Chromatography

Hunan Normal University
2025

Institute of Nanotechnology
2025

Lanzhou University
2025

China University of Geosciences
2025

Guangdong University of Technology
2017-2024

Huazhong Agricultural University
2021-2023

Lanzhou University of Technology
2023

Henan Provincial People's Hospital
2023

Zhengzhou University
2023

Xuzhou Medical College
2020-2022

Wind power is of strategic importance for reducing carbon dioxide emissions, minimizing environmental pollution, and enhancing the sustainability energy supply. Health monitoring wind turbines a crucial technology to ensure quality grid-connected power. Insufficient labeled data class imbalance problems are two critical issues intelligent fault diagnosis turbines. In this article, an method based on stacked capsule autoencoders proposed address inadequate imbalance. A prior knowledge-based...

10.1109/tii.2024.3424211 article EN IEEE Transactions on Industrial Informatics 2024-07-22

As bacteria continue to develop resistance toward current antibiotics, we find ourselves in a continual battle identify new antibacterial agents and targets. We report herein class of boron-containing compounds termed borinic esters that have broad spectrum activity with minimum inhibitory concentrations (MIC) the low microgram/mL range. These were identified by screening for inhibitors against Caulobacter crescentus CcrM, an essential DNA methyltransferase from Gram negative...

10.1021/jm050676a article EN Journal of Medicinal Chemistry 2005-10-26

Online streaming feature selection has garnered widespread attention due to its efficiency and adaptability in dynamic data environments. However, existing methods primarily focus on the correlation redundancy among features, often overlooking complementarity between candidate selected features. In this paper, we address gap by introducing three key innovations. First, construct a novel metric, fuzzy Gini entropy (FGE), measure uncertainty within datasets. Unlike traditional information...

10.1109/tfuzz.2025.3529466 article EN IEEE Transactions on Fuzzy Systems 2025-01-01

Abnormal development and mortality in early life stages pose significant threats to the growth continuation of fish populations. Tris(2,4-di-tert-butylphenyl) phosphate (TDtBPP) is a novel organophosphate ester contaminant detected natural waters. However, potential effects maternal exposure TDtBPP on offspring embryos remain unknown. Here, 30-day-old zebrafish were exposed at 0, 50, 500, or 5000 ng/L for 180 days, females spawned with unexposed males. accumulation was embryos, accompanied...

10.1021/acs.est.4c14581 article EN Environmental Science & Technology 2025-03-14

Benzoxaboroles are a novel class of drug-like compounds that have been rich sources inhibitors for various enzymes and new drugs. While examining benzoxaborole activity in phenotypic screens, our attention was attracted by the (aminomethylphenoxy)benzoxaborole family, which potently inhibited Toll-like receptor–stimulated cytokine secretion from leukocytes. After considering their structure-activity relationships central role kinases leukocyte biology, we performed kinome-wide screen to...

10.1124/jpet.113.207662 article EN Journal of Pharmacology and Experimental Therapeutics 2013-09-18

The nitrones α-phenyl-N-tert-butyl nitrone (PBN), sodium 2-sulfophenyl-N-tert-butyl (S-PBN) and disodium 2,4-disulfophenyl-N-tert-butyl (NXY-059) are neuroprotective in a variety of rodent models. objective the current studies was to compare ability PBN, S-PBN, NXY-059 form radical adducts prevent salicylate oxidation an aqueous system. For electron spin resonance (ESR) studies, hydroxyl radicals were generated with ultraviolet (UV) light hydrogen peroxide. Secondary then produced by...

10.1080/10715760100300351 article EN Free Radical Research 2001-01-01

Inducible nitric oxide synthase (iNOS) is a major source of during inflammation whose activity thought to be controlled primarily at the expression level. The B1 kinin receptor (B1R) post-translationally activates iNOS beyond its basal via extracellular signal regulated kinase (ERK)-mediated phosphorylation Ser(745) . Here we identified signalling pathway causing activation in cytokine-treated endothelial cells or HEK293 transfected with and B1R. To allow kinetic measurements release, used...

10.1111/j.1582-4934.2009.00992.x article EN other-oa Journal of Cellular and Molecular Medicine 2009-12-10

<b><i>Objectives:</i></b> To evaluate the efficacy and safety of mini- percutaneous nephrolithotomy (PCNL) in treatment large impacted proximal ureteral stones. <b><i>Methods:</i></b> We retrospectively reviewed outcomes 163 patients who underwent mini-PCNL between January 2006 August 2010. Mean age was 48.6 years mean stone size 18.4 mm. Hydronephrosis and/or hydroureterosis appeared all patients. In prone position, access (16-Fr sheath)...

10.1159/000343668 article EN cc-by-nc Urologia Internationalis 2013-01-01

The expression of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-12 (pp-GalNAc-T12) was studied in 3 normal human tissues (stomach, small intestine and colon), stomach 6 colon cancer cell lines, as well the resected (control) from 19 patients with colorectal cancer.Marathon Ready cDNAs were used templates tissues. mRNA extracted lines tissues, reverse-transcribed to cDNA. pp-GalNAc-T12 determined a real-time polymerase chain reaction (PCR).It found that strong weak or negligible 9...

10.1159/000081328 article EN Oncology 2004-01-01
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