A5100416975- Galectins and Cancer Biology
- Phytochemistry and Bioactive Compounds
- Phytochemical Studies and Bioactivities
- Aldose Reductase and Taurine
- Toxin Mechanisms and Immunotoxins
- Pancreatic and Hepatic Oncology Research
- Cancer Mechanisms and Therapy
- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Vascular Tumors and Angiosarcomas
Chongqing University
2023
Fuling Center Hospital of Chongqing
2023
Wenzhou Medical University
2019-2022
First Affiliated Hospital of Wenzhou Medical University
2019-2022
Testicular structural and functional impairment is a serious complication in male diabetes mellitus (DM) patients that leads to impaired fertility adulthood. In contrast other endocrine therapies, islet transplantation (IT) can effectively prevent even reverse diabetic nephropathy myocardial damage. However, whether IT alleviate diabetes-induced testicular injury remains unclear. this study, we sought investigate the effect of on A rat model was established by streptozotocin injection. DM,...
ABSTRACT Background Periplocin is a monomeric compound that exhibits anti‐tumor activities. It extracted from Cortex Periplocae. Objective This study aimed at determining the effect of periplocin treatment on apoptosis and proliferation human pancreatic cancer cells, to elucidate its mechanisms action. Methods PANC1 cfpac1 cells were treated with periplocin. Cell was detected by RTCA, Ki67 immunofluorescence, clonogenic assay. The transwell assay used examine cell migration invasion...
DT-13, the principal active component of Mysidium shortscapes from Liliaceae family, has garnered substantial interest in cancer therapy owing to its potential anticancer properties. This study investigated effects DT-13 on proliferation and apoptosis human pancreatic cell lines aimed elucidate underlying mechanisms. PANC1 CFPAC1 cells were exposed their was assessed using RTCA clone formation assays. Apoptotic protein expression analyzed by western blotting, apoptotic identified flow...
Periplocin, a natural compound, has been shown to induce apoptosis in variety of cancer cells. However, no research conducted demonstrate that Periplocin regulatory effect on autophagy. This study is aimed determine the treatment autophagy human pancreatic cells, as well underlying mechanisms. Pancreatic cells were treated with different concentrations and real-time cell analysis (RTCA), colony formation assay, Ki67 immunofluorescence detection used proliferation. Autophagy protein was...