A5037803408- Bacterial biofilms and quorum sensing
- Biochemical and Structural Characterization
- Electrospun Nanofibers in Biomedical Applications
- Microplastics and Plastic Pollution
- Bacterial Genetics and Biotechnology
- 3D Printing in Biomedical Research
- Molecular Communication and Nanonetworks
- Advanced Cellulose Research Studies
- Antibiotic Resistance in Bacteria
- Microfluidic and Bio-sensing Technologies
- Nicotinic Acetylcholine Receptors Study
- Surface Modification and Superhydrophobicity
- Polysaccharides Composition and Applications
- Pickering emulsions and particle stabilization
- Vibrio bacteria research studies
- Recycling and Waste Management Techniques
- Bacteriophages and microbial interactions
- Luminescence and Fluorescent Materials
- Molecular Sensors and Ion Detection
- Proteins in Food Systems
- Innovative Microfluidic and Catalytic Techniques Innovation
- Silk-based biomaterials and applications
- Insect and Arachnid Ecology and Behavior
- Nanoparticles: synthesis and applications
Aalto University
2018-2024
Three-dimensional (3D) printing has been an emerging technique to fabricate precise scaffolds for biomedical applications. Cellulose nanofibril (CNF) hydrogels have attracted considerable attention as a material 3D because of their shear-thinning properties. Combining cellulose with alginate is effective method enable cross-linking the printed in presence Ca2+ ions. In this work, spherical colloidal lignin particles (CLPs, also known nanoparticles) were used prepare CNF-alginate-CLP...
Microplastics accumulate in various aquatic organisms causing serious health issues, and have raised concerns about human by entering our food chain. The recovery techniques for the most challenging colloidal fraction are limited, even analytical purposes. Here we show how a hygroscopic nanocellulose network acts as an ideal capturing material tiniest nanoplastic particles. We reveal that entrapment of particles from aqueous environment is primarily result network's nature - feature which...
Producing hydrogels capable of mimicking the biomechanics soft tissue remains a challenge. We explore potential plant-based as polysaccharide tragacanth gum and antioxidant lignin nanoparticles in bioactive multicomponent for engineering. These natural components are combined with TEMPO-oxidized cellulose nanofibrils, material known shear thinning behavior. Hydrogels presented (TG) concentration-dependent rheological properties suitable extrusion 3D printing. TG enhanced swelling capacity up...
Recent developments suggest that the phase transition of natural and synthetic biomacromolecules represents an important ubiquitous mechanism underlying structural assemblies toward fabrication high-performance materials. Such a results in formation condensed liquid droplets, described as condensates or coacervates. Being able to effectively control assembly such entities is essential for tuning quality their functionality. Here we describe how self-coacervation genetically engineered...
Abstract The limited diversity in targets of available antibiotic therapies has put tremendous pressure on the treatment bacterial pathogens, where numerous resistance mechanisms that counteract their function are becoming increasingly prevalent. Here, we utilize an unconventional anti-virulence screen host-guest interacting macrocycles, and identify a water-soluble synthetic macrocycle, Pillar[5]arene, is non-bactericidal/bacteriostatic mechanism action involves binding to both homoserine...
The engineering of microbial systems increasingly strives to achieve a co-existence and co-functioning different populations. By creating interactions, one can utilize combinations cells where each population has specialized function, such as regulation or sharing metabolic burden. Here we describe microfluidic system that enables long-term independent growth fixed distinctly separate populations, while allowing communication through thin nano-cellulose filter. Using quorum-sensing...
Using supramolecular host molecules to hinder bacterial quorum sensing (QS) is a potential approach in circumventing antimicrobial resistance (AMR). The emergent family of pillararenes offers promising candidates for binding homoserine lactones (HSLs), signaling used by gram-negative species, including WHO critical-priority antibiotic-resistant bacteria. Here, we compare seven cationic against four HSLs, from (supra)molecular interactions biological assays. Complexation, characterized dye...
Abstract Particle‐stabilized emulsions, so‐called Pickering emulsions (PEs), are a promising low‐tech avenue to precisely engineered materials for applications in drug delivery, catalysis, or water remediation. The particle assembly at the liquid–liquid interface provides superior stability and an adjustable permeability, which is key parameter controllable compound capture release. However, understanding complex factors that control detail still‐remaining challenge limiting practical of PEs...
Abstract Microplastics accumulate to various aquatic organisms causing serious health issues, and they have raised concerns about human by entering our food chain. The recovery techniques for the most challenging colloidal fraction even analytical purposes are limited. Here we show how hygroscopic nanocellulose network acts as an ideal capturing material tiniest nanoplastic particles. We reveal that entrapment of particles from aqueous environment is a result network’s nature - feature which...
Quorum sensing (QS) serves as a vital means of intercellular signalling in variety prokaryotes, which enables single cells to act multicellular configurations. The potential control community-wide responses has also sparked numerous recent biotechnological innovations. However, our capacity utilize communication is hindered due scarcity complementary systems and restricted comprehension interconnections between these caused by variations their dynamic range. In this study, we uniform...
Abstract Quorum sensing (QS) serves as a vital means of intercellular signalling in variety prokaryotes, which enables single cells to act multicellular configurations. The potential control community‐wide responses has also sparked numerous recent biotechnological innovations. However, our capacity utilize communication is hindered due scarcity complementary systems and restricted comprehension interconnections between these caused by variations their dynamic range. In this study, we...
Abstract The limited diversity in targets of available antibiotic therapies has put tremendous pressure on the treatment bacterial pathogens, where numerous resistance mechanisms that counteract their function are becoming increasingly prevalent. Here, we utilize an unconventional anti-virulence screen host-guest interacting macrocycles, and identify a water-soluble synthetic macrocycle, Pillar[5]arene, is non-bactericidal/bacteriostatic mechanism action involves binding to both homoserine...
Graphical Abstract The wide chemical diversity in bacterial languages is explored the Research Article by Markus B. Linder et al. (e202314469). structural similarities were mapped theoretically and sets of both closely related widely diverging ligand structures experimentally investigated. results suggest that quorum sensing ligands can be used as a starting point to predict non-cognate binding intercellular signalling systems. Orthogonal systems could significantly advance our engineering...