A5030067311- Advanced Cellulose Research Studies
- Electrospun Nanofibers in Biomedical Applications
- 3D Printing in Biomedical Research
- Microfluidic and Bio-sensing Technologies
- Polysaccharides Composition and Applications
- Polysaccharides and Plant Cell Walls
- Lignin and Wood Chemistry
- Silk-based biomaterials and applications
- biodegradable polymer synthesis and properties
- Cellular Mechanics and Interactions
- Hydrogels: synthesis, properties, applications
- Wound Healing and Treatments
- Advanced Sensor and Energy Harvesting Materials
- Biofuel production and bioconversion
- Electrohydrodynamics and Fluid Dynamics
Aalto University
2021-2024
University of Helsinki
2024
Universidade de São Paulo
2021-2023
The current study provides a comprehensive rheology and survey on direct ink writing of xanthan gum/cellulose nanocrystal (XG/CNC) bio-inks for developing 3D geometries that mimic soft tissue engineering scaffolds' physical mechanical properties. presence CNC was found to be critical prerequisite the printability XG bio-inks; accordingly, hybrid XG/CNC revealed excellent viscoelastic properties enabled precise control hydrogel shaping printing lattice structures composed up eleven layers...
We report a facile strategy to prepare chitosan (CS) hydrogels that eliminates the need for chemical crosslinking advanced biomedical therapies. This approach gives controlled properties by incorporating natural bioactive phenolic compound, phloroglucinol (PG), into their microstructure. The adsorption of PG onto CS chains enhanced hydrogels' antioxidant activity up 25 % and resulted in denser, more entangled structure, reducing pore size 59 μm while maintaining porosity above 94 %. allowed...
Plant-based hydrogels have attracted great attention in biomedical fields since they are biocompatible and based on natural, sustainable, cost-effective, widely accessible sources. Here, we introduced new viscoelastic bio-inks composed of quince seed mucilage cellulose nanofibrils (QSM/CNF) easily extruded into 3D lattice structures through direct ink writing ambient conditions. The QSM/CNF inks enabled precise control printing fidelity where CNF endowed objects with shape stability after...
Producing hydrogels capable of mimicking the biomechanics soft tissue remains a challenge. We explore potential plant-based as polysaccharide tragacanth gum and antioxidant lignin nanoparticles in bioactive multicomponent for engineering. These natural components are combined with TEMPO-oxidized cellulose nanofibrils, material known shear thinning behavior. Hydrogels presented (TG) concentration-dependent rheological properties suitable extrusion 3D printing. TG enhanced swelling capacity up...
The recent FDA decision to eliminate animal testing requirements emphasises the role of cell models, such as spheroids, regulatory test alternatives for investigations cellular behaviour, drug responses, and disease modelling. influence environment on spheroid formation are incompletely understood, leading uncertainty in matrix selection scaffold-based 3D culture. This study uses atomic force microscopy-based techniques quantify adhesion Matrigel cellulose nanofibrils (CNF), cell-cell...