A5013273635- RNA Research and Splicing
- Genomics and Chromatin Dynamics
- RNA and protein synthesis mechanisms
- Sexual Differentiation and Disorders
- Insect behavior and control techniques
- Modular Robots and Swarm Intelligence
- Adipose Tissue and Metabolism
- Plant Molecular Biology Research
- Insect Resistance and Genetics
- Advanced biosensing and bioanalysis techniques
- Pancreatic function and diabetes
- Diet and metabolism studies
- RNA modifications and cancer
- Neurobiology and Insect Physiology Research
- Insect and Arachnid Ecology and Behavior
- Genomics and Rare Diseases
- Genetics, Aging, and Longevity in Model Organisms
Jackson Laboratory
2021-2024
University of Maine
2021-2023
Maine Medical Center Research Institute
2021
Maine Medical Center
2021
University of Dayton
2011-2015
Cis-regulatory elements (CREs) control gene expression, orchestrating tissue identity, developmental timing and stimulus responses, which collectively define the thousands of unique cell types in body
Abstract Cis -regulatory elements (CREs) control gene expression, orchestrating tissue identity, developmental timing, and stimulus responses, which collectively define the thousands of unique cell types in body. While there is great potential for strategically incorporating CREs therapeutic or biotechnology applications that require specificity, no guarantee an optimal CRE intended purpose has arisen naturally through evolution. Here, we present a platform to engineer validate synthetic...
The origination and diversification of morphological characteristics represents a key problem in understanding the evolution development. Morphological traits result from gene regulatory networks (GRNs) that form web transcription factors, which regulate multiple cis-regulatory element (CRE) sequences to control coordinated expression differentiation genes. formation modification GRNs must ultimately be understood at level individual linkages (i.e., factor binding sites within CREs)...