- SARS-CoV-2 and COVID-19 Research
- Acute Kidney Injury Research
- COVID-19 Clinical Research Studies
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Blood Pressure and Hypertension Studies
- Renal and Vascular Pathologies
- Hormonal Regulation and Hypertension
- Muscle and Compartmental Disorders
- COVID-19 Impact on Reproduction
- Diet and metabolism studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hemoglobin structure and function
- Heart Failure Treatment and Management
- MRI in cancer diagnosis
- Erythropoietin and Anemia Treatment
- Long-Term Effects of COVID-19
- Liver Disease Diagnosis and Treatment
- Cholinesterase and Neurodegenerative Diseases
- Electrolyte and hormonal disorders
- Pregnancy and preeclampsia studies
- Biomedical Research and Pathophysiology
- Cardiovascular Disease and Adiposity
- Alzheimer's disease research and treatments
- Renal Diseases and Glomerulopathies
Nazareth Hospital EMMS
2015-2024
Bar-Ilan University
2014-2024
Carmel Medical Center
2024
Clalit Health Services
2024
Rebecca Sieff Hospital
2021
Mission Hospital
2016
Rambam Health Care Campus
2015
Engulfed by the grave consequences of coronavirus disease 2019 (COVID-19) pandemic, a better understanding unique pattern viral invasion and virulence is utmost importance. Angiotensin (Ang)-converting enzyme (ACE) 2 key component in COVID-19 infection. Expressed on cell membranes target pulmonary intestinal host cells, ACE2 serves as an anchor for initial homing, binding to spike-protein domains enable entry into cells subsequent replication. Viral attachment facilitated multiplicity...
Determining the presence and characteristics of vascular flow is an essential part sonography interrogation. However, small vessels low velocities are not always possible to depict with conventional color power Doppler ultrasound. This can be frustrating, especially when diagnosis depends mainly on existence flow, sonographic examination will inconclusive, further imaging examinations required delayed. Superb microvascular (SMI) a novel mode, which provides visualization velocity flow. SMI...
Acute kidney injury (AKI) is a common clinical problem that still lacks effective treatment. Phosphodiesterase-5 (PDE5) inhibitors possess anti-apoptotic and anti-oxidant properties, making it promising therapy for ischemia-reperfusion (I/R) of various organs. The present study evaluated the early nephroprotective effects Tadalafil, PDE5 inhibitor, in an experimental model renal I/R. Sprague-Dawley rats were divided into two groups: vehicle-treated I/R (n = 10), Tadalafil (10 mg/kg...
Background and objectives: The short-term reported antibody response to SARS-COV-2 vaccination in dialysis patients is high, with a seroconversion rate up 97%. Data on the long-term durability of this are scarce. Our objective was characterize anti-spike level patients. Design, setting, participants, measurements: In an observational study, we measured levels who completed 2 doses BNT162b2 mRNA SAR S-COV-2 vaccine at 1, 3 6 months after second dose. We compared were infected COVD-19 control...
Superb microvascular imaging (SMI) is an innovative ultrasound image processing technique that provides greater detail and better visualization of small branching vessels. We assume SMI will provide sufficient information regarding the severity chronic kidney disease (CKD) reflecting histological changes.The aims was to assess capabilities early detection dysfunction renal fibrosis in comparison reference standard biopsy for diagnosis fibrosis.SMI performed patients (n = 52) with CKD stage...
Hemodialysis patients are susceptible to excess volume accumulation, particularly over the 2-day interval (long interdialytic gap), resulting in higher weight gain (IDWG). We thought determine whether a novel device designed enhance fluid and salt loss by activating eccrine sweat glands can mitigate IDWG. Patients eligible for study were undergoing regular hemodialysis ≥3 months, without residual renal function, with IDWG (as percentage of IDWG/dry body weight) ≥2.5%. Treatments administered...
Brown tumors are rare focal giant cell lesions of the bone caused by primary hyperparathyroidism (HPT). tumor was reported in 1891; it presents as end-stage findings HPT. Common involvements skull and pelvic girdle. We describe a case 46-year-old female hemodialysis patient, with secondary HPT whom multiple masses left maxillary sinus frontal were radiologically suspected to be brown tumor. This unusual manifestation can expected occur increased longevity patients renal failure illustrates...
Elevated intra-abdominal pressure (IAP) occurs in many clinical settings, including sepsis, severe acute pancreatitis, decompensated heart failure, hepatorenal syndrome, resuscitation with large volume, mechanical ventilation high intrathoracic pressure, major burns, and acidosis. Although increased IAP affects several vital organs, the kidney is very susceptible to adverse effects of elevated IAP. Kidney dysfunction among earliest physiological consequences In last two decades, laparoscopic...
Abstract Background Medication non adherence is a global epidemic perplexing phenomenon that eminent, but not insurmountable. Our first objective was to explore whether providing pharmacist's counseling cardiac patients prior discharge can increase patient's medication adherence, and our second assess better leads reduction of hospital readmissions. Methods Observational study conducted among diagnosed using an intervention strategy at from two hospitals in Israel; The Nazareth the Haemek...
Heart failure (HF) is characterized by the activation of adverse neurohormonal systems and a high mortality rate. Noteworthy, HF well-known complication chronic kidney disease (CKD), especially in end-stage (ESKD), where dialysis patients are seven to eight times more likely encounter cardiac arrest than general population. Therefore, it important develop efficient treatments improve function eventually reduce cardiovascular death toll. Sacubitril/valsartan (Sac/Val) dual inhibitor/blocker...
Ischemic acute kidney injury (iAKI) in diabetes mellitus is associated with a rapid deterioration of function, more than nondiabetic subjects. TVP1022, non-MAO inhibitor S-isomer rasagiline, possesses antioxidative and antiapoptotic activities. The current study examines the effects TVP1022 tempol on iAKI diabetic rats. Diabetes was induced by streptozotocin. clamping left renal artery for 30 min both right intact served as control. Forty-eight hours following ischemia, urinary flow (V),...
Objective: The present study assesses whether phosphodiesterase type 5 (PDE-5) inhibitor or carnitine exert nephroprotective effects against clinical contrast-induced nephropathy (CIN).Materials and Methods: consisted of three groups CKD patients. first group was control group, who were treated with N-acetyl-L-cysteine 1 day before on the radiocontrast administration. second one where patients infused over 10 min 2 h prior to administration 24 post CT. third PDE-5 given tadalafil in...
Abstract P seudomonas oryzihabitans ( . orizyhabitans ) has already been reported both as a human and zoonotic pathogen. A few cases of bacteremia have among patients who underwent peritoneal dialysis. never on hemodialysis. We report the first case in chronic hemodialysis patient; this patient did not central venous catheter angioaccess potential portal entry.