A5014631183- Dialysis and Renal Disease Management
- Acute Kidney Injury Research
- Parathyroid Disorders and Treatments
- Chronic Kidney Disease and Diabetes
- Central Venous Catheters and Hemodialysis
- Renal and related cancers
- Muscle and Compartmental Disorders
- Renal Diseases and Glomerulopathies
- Organ Donation and Transplantation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Medical Imaging and Pathology Studies
- Gout, Hyperuricemia, Uric Acid
- Cardiac Ischemia and Reperfusion
- Kidney Stones and Urolithiasis Treatments
- SARS-CoV-2 and COVID-19 Research
- Non-Invasive Vital Sign Monitoring
- Bone health and treatments
- Diagnosis and Treatment of Venous Diseases
- Genomics and Rare Diseases
- Biomedical Ethics and Regulation
- Health and Conflict Studies
- Renal and Vascular Pathologies
- Artificial Intelligence in Healthcare
- Intestinal and Peritoneal Adhesions
- Vitamin C and Antioxidants Research
Carmel Medical Center
2009-2024
Rappaport Family Institute for Research in the Medical Sciences
2024
Technion – Israel Institute of Technology
2004-2024
Alzheimer's Association of Israel
2021
Acute kidney injury (AKI) is a common clinical problem that still lacks effective treatment. Phosphodiesterase-5 (PDE5) inhibitors possess anti-apoptotic and anti-oxidant properties, making it promising therapy for ischemia-reperfusion (I/R) of various organs. The present study evaluated the early nephroprotective effects Tadalafil, PDE5 inhibitor, in an experimental model renal I/R. Sprague-Dawley rats were divided into two groups: vehicle-treated I/R (n = 10), Tadalafil (10 mg/kg...
No AccessJournal of UrologyInvestigative Urology1 Apr 2013Urinary NGAL and KIM-1: Biomarkers for Assessment Acute Ischemic Kidney Injury Following Nephron Sparing Surgery Zaid Abassi, Amjad Shalabi, Rima Sohotnik, Omri Nativ, Hoda Awad, Bishara Bishara, Victor Frajewicki, Igor Sukhotnik, Abeer Abbasi, Ofer Nativ AbassiZaid Abassi Department Physiology Biophysics, Rappaport Faculty Medicine, Haifa, Israel Rambam Research Unit, , ShalabiAmjad Shalabi General Surgery, Medical Center,...
Cohen-Hagai, Keren; Goldman, Shira; Wald, Ron; Frajewicki, Victor; Chernin, Gil; Iaina, Nomy Levin; Beckerman, Pazit; Antebi, Alon; Haviv, Yosef S; Benchetrit, Sydney; Rozen-Zvi, Benaya; On behalf of the Israeli Society Nephrology and Hypertension Author Information
The aim of this study is to investigate whether NGAL, given its advantages over traditional biomarkers, can be used describe the dynamic characteristics renal tubulointerstitial insult caused by adenine. Subsequently, it will possible assess NGAL as a biomarker any acute kidney injury, on top chronic interstitial disease, if levels are stable through phase our adenine model. Study group rats were fed an diet, and control regular diet only. Blood urine samples for urea, creatinine drawn from...
Atrial natriuretic peptide (ANP) plays an important role in blood volume and electrolyte homeostasis normovolemia hypervolemic states. The currently available information on the effects of hypovolemia plasma ANP is contradictory. Moreover, possible regulation receptors during severe hemorrhagic has not been investigated. This study evaluated hemorrhage glomerular receptor subtypes anesthetized rats. Constant rate bleeding 50% total within 2 h induced a reproducible shock state characterized...
To determine whether quantitative bone scintigraphy (QBS) with single-energy photon emission computed tomography (SPECT) can help predict which patients chronic renal disease will show mineral density (BMD) loss.In 18 patients, the percentage of injected dose technetium-99m methylene diphosphonate per cubic centimeter was measured QBS SPECT in lumbar vertebrae and femoral neck. The differences BMD over an average 20 months were compared measurements. values also serum turnover markers.There...
<i>Background:</i> Icodextrin, an effective osmotic substance that has been proposed as alternative agent for peritoneal dialysis induces ultrafiltration over long dwells. This study examines the transport after exposure to Icodextrin in rats. <i>Methods:</i> Animals were divided 4 groups and injected daily 30 days with 7.5 % (n = 14), Glucose 4.25 19) or glucose 4.25% plus 13). Rats of control group 15) not exposed. A 4-hour permeability was performed using at 1, 60....
Prevalence of End Stage Renal Disease (ESRD) is increasing worldwide. In the last years, age at onset dialysis treatment also rising. Today more than 50% patients in maintenance have a mean 65. For 20 years responsible for this prevalence population aged 75 or year- old. Mortality during subpopulation has been reported as high first 2 dialysis. Data about 80 scarce and inconclusive.
Abstract Background and Aims Successful peritoneal dialysis (PD) program requires a combination of optimal access low incidence complications. Between pitfalls this modality are early mechanical complications such as leak, malfunction, new abdominal wall hernia formation in the long term PD treatment. Pre-existing is relative contraindication for PD. Hernias also known not uncommon complication over course one causes technique failure. In our center, physical examination an ultrasound...
Kushnir, Daniel; Tanasiychuk, Tatiana; Kayali, Jawad; Frajewicki, Victor Author Information