A5054464030- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Gastrointestinal motility and disorders
- Pharmacological Effects and Toxicity Studies
- Clostridium difficile and Clostridium perfringens research
- Human-Animal Interaction Studies
- Animal Behavior and Welfare Studies
- Advancements in Transdermal Drug Delivery
- Microfluidic and Capillary Electrophoresis Applications
- Inflammatory Bowel Disease
- Blood disorders and treatments
- Microscopic Colitis
- Veterinary Practice and Education Studies
- Medical Imaging Techniques and Applications
- Nanoparticle-Based Drug Delivery
- Neonatal Health and Biochemistry
University of Copenhagen
2017-2024
Danish National Research Foundation
2021
Technical University of Denmark
2021
The Velux Foundations
2021
The Danish antibiotic use guidelines for companion animal practice were published by the Veterinary Association in 2012. Since then, national surveillance data indicate a 10% reduction total of antibiotics animals, particularly marked third generation cephalosporins. aim study was to assess if and how have impacted diagnostic prescription habits users, identify user perceived barriers implementation. An online questionnaire sent all 882 members Small Animal October 2015. survey completed 151...
Abstract The mucus layer in the small intestine is generally regarded as a barrier to drug absorption. However, complex system, and presently, only few studies have been conducted elucidate its physicochemical properties. current study hypothesizes that contains solubility-enhancing surfactants thus might aid oral absorption of poorly water-soluble drugs. Mucus was sampled from sections fasted rats analyze rheological properties determine pH concentrations proteins endogenous surfactants,...
Microscale devices are promising tools to overcome specific challenges within oral drug delivery. Despite the availability of advanced high-quality imaging techniques, visualization and tracking microscale in gastrointestinal (GI) tract is still a challenge. This work explores possibilities applying planar X-ray computed tomography (CT) scanning for GI rats. Microcontainers (MCs) an example that have shown great potential as delivery system. Barium sulfate (BaSO4) loaded into cavity MCs...
Mild analgesics have been associated with antiandrogenic effects, but there are no such studies on dipyrone, despite its high prevalence of use in many countries. We examined the production steroid hormones human H295R cells after exposure to dipyrone and two metabolites, 4-Methylaminoantipyrine (MAA) 4-Aminoantipyrine (AA), as well fetal testicular testosterone rats following maternal exposure. Androgen agonistic/antagonistic effects were vitro for metabolites Yeast Screen (YAS) assay vivo...
Abstract The mucus layer in the small intestinal is generally regarded as a barrier to drug absorption. However, complex system, and presently, only few studies have been conducted elucidate its physicochemical properties. current study hypothesizes that contains solubility-enhancing surfactants thus might aid oral absorption of poorly water-soluble drugs. Mucus was sampled from sections intestine fasted rats analyze rheological properties determine pH concentrations proteins endogenous...