- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Neuroscience and Music Perception
- Multisensory perception and integration
- EEG and Brain-Computer Interfaces
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health Research Topics
- Transcranial Magnetic Stimulation Studies
- Visual perception and processing mechanisms
- Advanced MRI Techniques and Applications
- Hearing Loss and Rehabilitation
- Advanced Neuroimaging Techniques and Applications
- Heart Rate Variability and Autonomic Control
- Olfactory and Sensory Function Studies
- Tactile and Sensory Interactions
- Action Observation and Synchronization
- Bullying, Victimization, and Aggression
- Child and Adolescent Psychosocial and Emotional Development
- Face Recognition and Perception
- Traumatic Brain Injury Research
- Diverse Music Education Insights
- Neurotransmitter Receptor Influence on Behavior
- Motor Control and Adaptation
- Neurobiology of Language and Bilingualism
RWTH Aachen University
2013-2022
Universitätsklinikum Aachen
2006-2022
Jülich Aachen Research Alliance
2011-2021
Cuban Neuroscience Center
2021
Brain (Germany)
2010-2020
Forschungszentrum Jülich
2007-2016
Westfälische Hochschule
2008
Abstract Mental imagery is a complex cognitive process that resembles the experience of perceiving an object when this not physically present to senses. It has been shown that, depending on sensory nature object, mental also involves correspondent neural mechanisms. However, it remains unclear which areas brain subserve supramodal processes are independent modality, and involved in modality‐specific processes. Here, we conducted functional magnetic resonance imaging study reveal networks for...
In magnetoencephalography (MEG) and electroencephalography (EEG), independent component analysis is widely applied to separate brain signals from artifact components. A number of different methods have been proposed for the automatic or semiautomatic identification Most are based on amplitude statistics decomposed MEG/EEG signal. We present a fully automated approach phase MEG isolation biological artifacts such as ocular, muscle, cardiac (CAs). The performance measures was investigated....
Major theories on the neural basis of schizophrenic core symptoms highlight aberrant salience network activity (insula and anterior cingulate cortex), prefrontal hypoactivation, sensory processing deficits as well an impaired connectivity between temporal cortices. The mismatch negativity is a potential biomarker schizophrenia its reduction might be consequence each these mechanisms. In contrast to previous electroencephalographic studies, functional magnetic resonance imaging may...
Cognitive functioning is impaired in patients with schizophrenia, leading to significant disabilities everyday functioning. Its improvement an important treatment target. Neurofeedback (NF) seems a promising method address the neural dysfunctions underlying those cognitive impairments. The anterior cingulate cortex (ACC), central hub for processing, one of brain regions known be dysfunctional schizophrenia. Here we conducted NF training based on real-time functional magnetic resonance...
Neurofeedback (NF) based on real-time functional magnetic resonance imaging (rt-fMRI) allows voluntary regulation of the activity in a selected brain region. For training this regulation, well-designed feedback system is required. Social reward may serve as an effective incentive NF paradigms, but its efficiency has not yet been tested. Therefore, we developed social paradigm and assessed it comparison with typical visual (moving bar). We trained 24 healthy participants, three consecutive...
Mismatch responses reflect neural mechanisms of early cognitive processing in the auditory domain. Disturbances these on multiple levels may contribute to clinical symptoms major depression (MD). A functional magnetic resonance imaging (fMRI) study was conducted identify neurobiological foundations altered mismatch MD. Twenty-five patients with and 25 matched healthy individuals completed an paradigm optimized for fMRI. Brain activity during compared between groups. Moreover, seed-based...
Auditory verbal hallucinations (AVHs) are a hallmark of schizophrenia and can significantly impair patients' emotional, social, occupational functioning. Despite progress in psychopharmacology, over 25% patients suffer from treatment-resistant hallucinations. In the search for alternative treatment methods, neurofeedback (NF) emerges as promising therapy tool. NF based on real-time functional magnetic resonance imaging (rt-fMRI) allows voluntarily change activity selected brain region – even...
Background: Post-traumatic stress disorder (PTSD) is characterized by deficits in the self-regulation of cognitions and emotions. Neural networks emotion regulation may exhibit reduced control mediated anterior cingulate cortex (ACC), contributing to aberrant limbic responses PTSD. Methods: Real-time fMRI neurofeedback (rt-fMRI NF) assessed ACC nine patients with PTSD after single trauma exposure matched healthy controls. All participants were instructed train upregulation on three training...
Traumatic experiences are associated with neurofunctional dysregulations in key regions of the emotion regulation circuits. In particular, amygdala responsivity to negative stimuli is exaggerated while engagement prefrontal regulatory control attenuated. Successful application (ER) strategies may counteract this disbalance, however, learned daily life hampered individuals afflicted by posttraumatic stress disorder (PTSD). We hypothesized that a single session real-time fMRI (rtfMRI) guided...
Psychomotor disturbance has been consistently regarded as an essential feature of depressive disorders. Studying objectively measurable motor behaviors like finger-tapping may help advance the diagnostic methods. Twenty-five patients with major disorder (MDD) and 15 healthy participants underwent functional magnetic resonance imaging (fMRI) measurements while tapping their index fingers. The (FT) task was performed by right hand (the frequency varied between 1, 2 4 Hz) or both hands either...
Impaired cognitive reappraisal, associated with the social functioning and well-being of patients affected by mood or anxiety disorders, is characterized distinct neural activation patterns across clinical populations. To date, studies dedicated to identifying common profiles need be clarified. The aim present study was investigate transdiagnostic differences commonalities in brain during reappraisal-mediated downregulation emotions.
Clinical observations and neuroimaging data revealed a right-hemisphere fronto-parietal-thalamic-brainstem network for intrinsic alertness, additional left fronto-parietal activity during phasic alertness. The primary objective of this fMRI study was to map the functional neuroanatomy alertness as precisely possible in healthy participants, using novel assessment paradigm already employed clinical settings. Both experimental design were optimized specifically assess while at same time...
Previous studies have indicated that the processes leading to resolution of emotional and non-emotional interference conflicts are unrelated, involving separate networks. It is also known conflict itself suggests a considerable overlap Our study an attempt examine how these findings may be related.We used functional magnetic resonance imaging (fMRI) neural responses 24 healthy subjects paradigms presentation congruent incongruent word-face pairs based on semantic incompatibility between...
The interaction of low perceptual stimulation or goal-directed behavior with a negative subjective evaluation may lead to boredom. This contribution boredom shed light on its neural correlates, which are poorly characterized so far. A video game served as simulation free interactive without interruption the game's narrative. Thirteen male German volunteers played first-person shooter (Tactical Ops: Assault Terror) during functional magnetic resonance imaging (fMRI). Two independent coders...
Affective disorders are associated with maladaptive emotion regulation strategies. In particular, the left more than right ventrolateral prefrontal cortex (vlPFC) may insufficiently regulate processing, e.g., in amygdala. A double-blind cross-over study investigated NF-supported cognitive reappraisal training major depression (
Semantic priming, a well-established technique to study conceptual representation, has thus far produced variable fMRI results, both regarding the type of priming effects and their correlation with brain activation. The aims current were (a) investigate two types semantic relations--categorical versus associative--under controlled processing conditions (b) whether categorical associative relations between words are correlated response enhancement or suppression. We used examine neural...