Venkatesan Srinivasadesikan

ORCID: 0000-0001-9533-1299
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About
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Research Areas
  • Molecular Sensors and Ion Detection
  • Luminescence and Fluorescent Materials
  • Electrochemical sensors and biosensors
  • X-ray Diffraction in Crystallography
  • Synthesis and biological activity
  • Crystallization and Solubility Studies
  • Click Chemistry and Applications
  • Synthesis and Characterization of Heterocyclic Compounds
  • Advanced biosensing and bioanalysis techniques
  • Analytical Chemistry and Sensors
  • Synthesis and Biological Evaluation
  • Crystallography and molecular interactions
  • Supramolecular Chemistry and Complexes
  • DNA and Nucleic Acid Chemistry
  • Advanced Photocatalysis Techniques
  • Chemical Reaction Mechanisms
  • Magnetism in coordination complexes
  • Advanced Chemical Physics Studies
  • Lanthanide and Transition Metal Complexes
  • Computational Drug Discovery Methods
  • Metal complexes synthesis and properties
  • Supramolecular Self-Assembly in Materials
  • Free Radicals and Antioxidants
  • Electrochemical Analysis and Applications
  • Catalytic Processes in Materials Science

Vignan's Foundation for Science, Technology & Research
2017-2025

Dr. Reddy's Laboratories (India)
2024

National Yang Ming Chiao Tung University
2014-2022

National Chung Cheng University
2009-2021

Guntur Medical College
2018-2020

Division of Chemistry
2018-2019

And Technology Research (United Kingdom)
2018

Texas State University
2017

National Hsinchu University of Education
2015

Chalcone and triazole scaffolds have demonstrated a crucial role in the advancement of science technology. Due to their significance, research has proceeded on design development novel benzooxepine connected 1,2,3-triazolyl chalcone structures. The new derivatives produced by methyl ketone 2 different aromatic carbonyl compounds 3 are discussed this paper. All prepared well-established structures variety spectral approaches, including mass analysis, 1H NMR, 13C IR. Among tested compounds,...

10.1016/j.heliyon.2024.e27773 article EN cc-by-nc Heliyon 2024-03-24

Two rhodamine hydrazine derivatives <bold>Rh1</bold> and <bold>Rh2</bold> with catechol ether functionalities have been synthesized utilized towards sequential colorimetric detections of Cu(<sc>ii</sc>) pyrophosphate (PPi) ions in a semi-aqueous medium.

10.1039/c6ra24472f article EN RSC Advances 2016-01-01

A novel multifunctional mechanically interlocked switchable [2]rotaxane R4 containing two molecular stations and rotaxane arms terminated with boron-dipyrromethene (BODIPY) fluorophores its derivatives were synthesized for the first time by CuAAC click reaction. The shuttling motion of macrocycle between dibenzylammonium triazolium recognition sites distance dependent photoinduced electron transfer process is demonstrated utilizing external chemical stimuli (acid/base). Interestingly,...

10.1021/acsami.5b07574 article EN ACS Applied Materials & Interfaces 2015-11-09

A simple anthracene-based <bold>AP</bold> probe was synthesized to detect Cu<sup>2+</sup> ions, <italic>via</italic> the photoinduced electron transfer mechanism, in live cells.

10.1039/c5nj03168k article EN New Journal of Chemistry 2016-01-01

Several bacterial targets are screened for the development of anti-infective medicines, but still finding new pharmacological and chemotherapeutics is necessary in this field. Many drugs Fab I inhibitors with center cores like pyridines, pyridones, benzoxazole, benzothiazoles, quinolines, quinazolines pyrazoles, etc. an advanced stage. In present work, we have designed simple efficient synthetic route novel molecules based on structure binding modes enzymes. The derivatives...

10.14233/ajchem.2025.33016 article EN Asian Journal of Chemistry 2025-02-28

Canonical Wnt signaling plays a key role in tumor cell proliferation which correlates with the accumulation of β-catenin resulting inactivation network targets such as GSK3β, Axin, CK1. Uncontrolled expression leads to different types cancers and other diseases sarcoma mesenchymal formation. However, is an attractive target for cervical cancer. In present study, compounds Doxorubicin Zinc conjugated were screened against using Molecular Docking, Dynamics Simulation, MM/GBSA, DFT approaches...

10.1371/journal.pone.0316665 article EN cc-by PLoS ONE 2025-04-07

Here, we report the design, synthesis, and optical behaviors of a multistimuli responsive [2]rotaxane system constructed from noncovalent interactions between diarylethene (DAE)-based axle tetraphenylethene (TPE)-based macrocycle using snapping supramolecular assembly approach. The shuttling behavior (Ring-TPE) dialkylammonium urea stations could be realized by influence acid-base stimuli 1H NMR spectroscopy. Switching open-form (OF) [2]rotaxanes (DAE-R1-OF DAE-R2-OF) is highly reversible...

10.1021/acs.joc.3c00077 article EN The Journal of Organic Chemistry 2023-04-19

Dual-emissive tetraphenylethene (TPE) and pyrene-containing amphiphilic molecules are of great interest because they can be integrated to form stimuli responsive materials with various biological applications. Herein, we report the study mechanically interlocked (MIMs) aggregation-induced static excimer emission (AISEE) property through a series TPE pyrene-based [2]rotaxanes, where t-butylcalix[4]arene hydrophobic nature was used as macrocycle. Evidently, by adorning pyrene units in...

10.1021/acsami.0c14107 article EN ACS Applied Materials & Interfaces 2020-09-28
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